Patents
Literature
Patsnap Copilot is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Patsnap Copilot

75results about How to "Maintain steady state" patented technology

Method for determining free vitamin D in sample through liquid chromatography tandem mass spectrometry

The present invention provides a method for determining free vitamin D in a sample through liquid chromatography tandem mass spectrometry. The method comprises: preparing free vitamin D standard substance solutions of different concentrations; adding stable isotope internal standard substances to the standard substance solutions, uniformly mixing, then extracting with n-hexane, drying supernatantswith nitrogen, adding PTAD for derivatization and then drying with the nitrogen, and adding a complex solution for detection of liquid chromatography tandem mass spectrometry; drawing a standard curve according to the concentrations of the standard substance solutions and the detected signal intensity; replacing the standard substance solution in step B with a sample to be determined for conducting detection; and obtaining the concentration of the free vitamin D in the sample to be determined according to the detection result of the sample to be determined with reference to the standard curve, thereby realizing quantitative detection of the free vitamin D in the sample. The present invention successfully establishes the method for determining the free vitamin D in the sample through liquid chromatography tandem mass spectrometry. The method can quickly and specifically detect the content of the free vitamin D in the sample (especially serum).
Owner:北京豪思生物科技股份有限公司

Feed additive capable of relieving endoplasmic reticulum stress of jewfishes as well as preparation method and application of feed additive

The invention relates to a feed additive capable of relieving endoplasmic reticulum stress of jewfishes as well as a preparation method and application of the feed additive, and belongs to the field of feeds. Each 100 parts by weight of the feed additive comprises 20-30 parts by weight of alfalfa sapinogenin, 10-20 parts by weight of chelated zinc methionine, 5-15 parts by weight of taurine, 20-30parts by weight of radix puerariae powder, 5-10 parts by weight of grape seed proanthocyanidins, and the balance of a carrier. The raw materials of the feed additive are safe and free from harmful remaining, and create conditions for production of a green feed and aquatic products. The preparation method of the feed additive comprises the following steps of mixing the raw materials in parts by weight. The preparation method is simple, good in condition controllability and good in stability, and has favorable application prospects. The feed additive is applied to preparation of a jewfish feed,the antioxidant ability of livers of the jewfishes can be improved, the oxidative damage of endoplasmic reticulum can be reduced, the endoplasmic reticulum stress protein expression can be reduced, the endoplasmic reticulum stress can be relieved, and the endoplasmic reticulum can be maintained stable.
Owner:JIMEI UNIV

Chinese herbal medicine additive for feeding laying hens and feeding method of additive

The invention discloses a Chinese herbal medicine additive for feeding laying hens and a feeding method of the additive. The Chinese herbal medicine additive is prepared from the following Chinese herbal medicines in parts by weight of 3-6 parts of rhizoma atractylodis macrocephalae, 2-5 parts of radix astragali, 1-4 parts of radix platycodonis, 1-4 parts of herba epimedii, 1-3 parts of radix angelicae sinensis, 2-4 parts of herba ephedrae, 2-5 parts of rhizoma dioscoreae, 3-6 parts of fructus hordei germinatus, 1-3 parts of massa medicata fermentata, 1-3 parts of pericarpium citri reticulatae, 2-4 parts of radix acanthopanacis semticosi and 1-3 parts of radix sanguisorbae. Various Chinese herbal medicines are ground and sieved, and the sieved materials are mixed in parts by weight to obtain a mixture, namely the Chinese herbal medicine additive. 1-3 kg of the Chinese herbal medicine additive is added into every 100 kg of chicken compound feed according to the weight ratio to obtain chicken feed. 10-36 g of the chicken feed is used for feeding each brooding chicken every day, 40-80 g of the chicken feed is used for feeding each growing chicken every day, and 85-120 g of the chickenfeed is used for feeding each laying hen every day. The additive has the characteristics of strong safety, small toxic and side effects and low residue, avoids tolerance of livestock and poultry to the additive, and basically realizes antibiotic-free breeding.
Owner:唐山市丰润区百草农业科技发展有限公司

Minimal hepatic encephalopathy intestinal flora regulating Chinese herbal preparation and preparation method thereof

The invention belongs to the field of drug processing and particularly relates to a minimal hepatic encephalopathy intestinal flora regulating Chinese herbal preparation and a preparation method thereof. The minimal hepatic encephalopathy intestinal flora regulating Chinese herbal preparation is mainly composed of kudzuvine root, coptis chinensis, red date, honeysuckle, red ginseng, semen coicis,ginsenoside, astragalus polysaccharides, gynostemma pentaphylla, clove tea extract, radix paeoniae alba, liquorice, eryngo, timosaponin, catechinic acid, apigenin, fructus evodiae, brucea javanica, lobelia chinensis, amaranthus retroflexus, frankincense, eucalyptus honey and lichen. The minimal hepatic encephalopathy intestinal flora regulating Chinese herbal preparation can accelerate intestinalperistalsis and promote defecation; during defecation, intestinal pernicious bacteria and unhealthy metabolites are excreted to improve intestinal flora disequilibrium; contained organic acids maintain an acid intestinal environment and reduce the pH of intestinal tracts to provide a suitable growing environment for intestinal probiotics. The minimal hepatic encephalopathy intestinal flora regulating Chinese herbal preparation can inhibit bacteria by damaging cytoderm synthesis, protein synthesis and genetic material synthesis of the bacteria.
Owner:广西中医药大学附属瑞康医院

Selenium-rich water and preparation method thereof

The invention discloses selenium-rich water, which consists of the following raw materials in parts by weight: 5-10 parts of a selenium source, 1-2 parts of a pH regulator, 1-3 parts of an antioxidant, 0.1-0.2 part of stabilizing and dispersing agents and 2,500-3,500 parts of water. The selenium-rich water disclosed by the invention adopts organic selenium and inorganic selenium to carry out mutual cooperation and supplementation, the organic selenium has a high price but has a good absorption effect, the inorganic selenium has a low price but has a poor absorption effect, so that the organicselenium and the inorganic selenium are cooperatively used, the absorption effect of the low-concentration inorganic selenium is obviously improved, and then, a certain amount of organic selenium is supplemented to reach a content required by the human body. While a situation that the price is not too high is guaranteed, the selenium element required by the human body is supplemented. In addition,the selenium-rich water disclosed by the invention adopts the pH regulator, the stabilizing agent and the dispersing agent to guarantee the stable state of the selenium-rich water, so that the selenium-rich water can be stored for a long time, the expiration date of the selenium-rich water is greatly prolonged, and the effective content of the selenium element of the selenium-rich water can be kept to a maximum extent, and the selenium-rich water has wide applicability.
Owner:深圳市名之洋生物科技有限公司

Application of brown algae oligosaccharide

The invention provides application of brown algae oligosaccharide or pharmaceutically acceptable salt thereof in preparation of a medicine for treating acute kidney injury, wherein the brown algae oligosaccharide is brown algae disaccharide, brown algae triose and / or brown algae tetraose. The invention also provides application of the brown algae oligosaccharide or the pharmaceutically acceptable salt thereof in preparation of medicines for preventing acute kidney injury from being converted into chronic kidney diseases. After the brown algae oligosaccharide is used for treating an animal with acute kidney injury, the serum creatinine level is obviously reduced, the urine concentration function of the kidney is obviously recovered, the levels of renal tubular injury factors (KIM-1 and NGAL) are obviously reduced, the expression of inflammatory factors is obviously reduced, the pathological change of the kidney is obviously improved, and the treatment effect is enhanced along with the increase of the dosage. Therefore, the brown algae oligosaccharide disclosed by the invention has a relatively strong effect of treating the acute kidney injury. In addition, when acute kidney injury occurs, the brown algae oligosaccharide disclosed by the invention can be used for protecting kidney functions and preventing the acute kidney injury from being converted into chronic kidney diseases.
Owner:HAITANG (JIANGSU) BIOTECHNOLOGY CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products