99 results about "Superparamagnetic iron oxide nanoparticles" patented technology

The invention relates to the technical field of sewage treatment, and in particular to preparation method of magnetic biochar loaded photosynthetic bacteria material and a sewage treatment method. The preparation method comprises the steps of: preparing a magnetic nano iron oxide material by a chemical coprecipitation method, conducting activation and expansion culture on photosynthetic bacteria, loading the nano iron oxide particles on the surface of biological carbon material through a self-assembly method to form a magnetic biochar; and loading the photosynthetic bacteria on the surface of the magnetic biochar through a co-incubation method, so as to obtain the magnetic biochar loaded photosynthetic bacteria material. The magnetic biochar loaded photosynthetic bacteria material is co-incubated with sewage for a period of time, so as to realize degradation of COD, ammonia nitrogen and phosphate radical in the sewage. The invention employs the electrostatic binding of high specific surface of the nano magnetic iron oxide and the bacteria with charge on the surface to achieve immobilization of strains, and magnetic iron oxide material has activation on strain enzyme, thereby enhancing the degradation of COD, ammonia nitrogen and phosphate radical by microbes.

The invention relates to a method for producing biological degradable magnetic nanometer particles, wherein said particle has corn and frame; the corn layer is magnetic ferric oxide; the frame is natural macromolecule materials as liposome, blood albumin, dope, starch, or chitose; its diameter is 1-100nm; the nanometer particles is prepared by reverse-phase micro emulsion method. The inventive particle has wide application.

The invention relates to d-glucosamine-modified iron oxide nanoparticles used as a tracer for magnetic resonance, a preparation method of lyophilized powder thereof and use thereof. The d-glucosamine-modified iron oxide nanoparticles comprise superparamagnetic iron oxide nanoparticles, wherein the surfaces of the superparamagnetic iron oxide nanoparticles are modified by a substance having carboxyls; the carboxyls react with the aminos of the d-glucosamine to form amido bonds; and thus a structure that the surfaces of the superparamagnetic iron oxide nanoparticles are modified by the d-glucosamine is formed. The invention provides a novel tumor-targeted MRI contrast agent which has high selectivity of tumors for the tumor targeted magnetic resonance diagnostic tests and clinic tumor diagnosis. By preserving the d-glucosamine-modified superparamagnetic iron oxide nanoparticles in form of the lyophilized powder, the unstable problem of the d-glucosamine-modified superparamagnetic iron oxide nanoparticles is solved. The d-glucosamine-modified iron oxide nanoparticles are sterile, anhemolytic and free from vascular stimulation and can meet the requirements of tests of cells, animals and the like.

The present invention relates to a magnetic carrier for an electrophotographic developer comprising spherical magnetic composite particles comprising a phenol resin as a binder and ferromagnetic iron oxide particles bonded to each other through the phenol resin, wherein the spherical magnetic composite particles have a ten-point mean roughness Rz of 0.3 to 2.0 μm. The magnetic carrier for an electrophotographic developer according to the present invention exhibits an excellent durability against peeling-off and abrasion of coating resins formed thereon and a high stability to mechanical stress exerted onto the carrier, is free from occurrence of spent toner, can be stably held over a long period of time without occurrence of fogging and unevenness in density of toner images, and can keep high-quality images with an excellent gradation for a long period of time.

The invention discloses a Fe3O4@SiO2@P4VP-PDMS-P4VP hybrid nanoparticle with pH and magnetic responsiveness and a preparation method thereof and an application of the hybrid nanoparticle in a nano oil-water separation emulsion. The Fe3O4@SiO2@P4VP-PDMS-P4VP hybrid nanoparticle is obtained by coupling reaction of a pyridine group on a P4VP block in a P4VP-PDMS-P4VP triblock copolymer with pH responsiveness with a C-I active group on the superparamagnetic iron oxide nanoparticles Fe3O4@SiO2 surface and bonding the P4VP-PDMS-P4VP triblock copolymer into the Fe3O4@SiO2 nanoparticle surface. The invention further specifically discloses the preparation method of the Fe3O4@SiO2@P4VP-PDMS-P4VP hybrid nanoparticle and the application of the Fe3O4@SiO2@P4VP-PDMS-P4VP hybrid nanoparticle in the nano oil-water separation emulsion. Due to the action of the central Fe3O4magnetic nanoparticle, the hybrid nanoparticle absorbing oil content can be easily separated from an aqueous system, and the oil absorbed hybrid nanoparticle can be recycled in an acid aqueous solution after absorption.

A magnetic toner is formed of magnetic toner particles each comprising at least a binder resin and a magnetic iron oxide. The magnetic toner is provided with improved developing performances by realizing an appropriate surface-exposure state of the magnetic iron oxide, which is represented by a wettability characteristic in methanol/water mixture liquids of the magnetic toner such that it shows a transmittance of 80% for light at a wavelength of 780 nm at a methanol concentration in a range of 65-75% and a transmittance of 20% at a methanol concentration in a range of 66-76%.

A toner showing a high transferability and suitable for use in cleanerless image forming system is formed of toner particles comprising at least a binder resin and magnetic iron oxide. The toner is characterized by a specific circularity distribution relative to its weight-average particle size and a controlled degree of surface-exposed magnetic iron oxide providing an extract solution with hydrochloric acid showing an absorbance of 1.0-2.5 at a wavelength of 340 nm. The toner is suitably produced by a production system including a rotary mechanical pulverizer and a one-pass surface treatment apparatus for continuously applying a mechanical impact force to pulverized toner particles therein.

The present invention provides the synthetic method and superparamagnetic iron oxide nanoparticles capable of targeting to the folic acid receptors existing on the cell membranes and with high relaxivity. The iron oxide nanoparticles of the present invention can further be used as the contrast agents for magnetic resonance imaging (MRI).

The invention discloses a folic acid mediated antitumor drug superparamagnetic tumor targeted nanoparticle. A superparamagnetic iron oxide nanoparticle is adopted as the carrier, and high temperature thermal decomposition method is employed to synthesize polyethylene glycol-polyethyleneimine modified uperparamagnetic iron oxide nanoparticle, then a folic acid ligand is grafted on the surface of iron oxide by chemical method, and then an antitumor drug is loaded into the iron oxide nanoparticle by electrostatic adsorption and hydrogen bonding, thus obtaining the folic acid mediated antitumor drug superparamagnetic tumor targeted nanoparticle. According to the invention, the dual targeting effect can strengthen the anti-tumor effect of the antitumor drugs, and the folic acid mediated antitumor drug superparamagnetic tumor targeted nanoparticle has small toxic and side effect, thus being a tumor treatment nanoparticle preparation with substantial development value.

The invention discloses a preparation method for a high-sensitivity bimodal magnetic resonance contrast agent. According to the preparation method, by means of a method for preparing ferric oleate andmanganese chloride through thermal decomposition, a high-boiling-point solvent is adopted as a reaction medium, oleic acid and oleylamine are used as stabilizers, and therefore manganese oxide embedded iron oxide nanoparticles with narrow particle size distribution and high degree of crystallinity are obtained. The invention particularly relates to a preparation method for modifying the manganeseoxide embedded iron oxide nanoparticles by utilizing the oleic acid/the oleamine, or a preparation method for the biocompatible and water-soluble manganese oxide embedded iron oxide nanoparticles. The preparation method for the high-sensitivity dual-mode magnetic resonance contrast agent has the advantages that the requirements of magnetic resonance imaging for the contrast agent and the characteristics of the Nanotechnology are combined, by means of regulation and control over chemical synthesis, manganese oxide with the T1 contrast capability and superparamagnetic iron oxide nanoparticles with the T2 contrast capability are combined so as to form the manganese oxide embedded iron oxide nanoparticles, and therefore the cooperatively-enhancing dual-mode magnetic resonance contrast effectcan be achieved between the two imaging modes, namely, the T1 imaging mode and the T2 imaging mode.

The invention relates to magnetic black iron oxide. A preparation process of the magnetic black iron oxide comprises the following steps of: (1), putting the mixture of ferric salt and ferrite into a container, adding a certain amount of water, and preparing a solution with the iron ion concentration of 1.0-2.0 mol/L; (2), adding ethanol and oleic acid into the container; (3), adjusting the pH of the solution in the container by using ammonia water till the pH is 1.0-1.4, and then, adjusting the pH by using liquid caustic soda till the pH is 7.4-8.1; (4), increasing the temperature of the container filled with a mixed solution after adjusting the pH; (5), filter-pressing, rinsing, drying and crushing at the beginning of increasing the temperature after reacting for 0.8-1.5 hours, and then obtaining the finished product. Because of adopting the technical scheme, the preparation process is lower in reaction temperature and shorter in process period; furthermore, the prepared finished product is higher in purity; the production energy consumption is reduced; the production cost is saved.

The invention discloses a siRNA conveying carrier. The active ingredient of the conveying carrier is nanaparticles formed by coupling superparamagnetic iron oxide nanoparticles and polyethylene glycol-polyethyleneimine. In addition, the invention also discloses a eukaryotic cell transfection liquid which comprises a composite made from siRNA and the siRNA conveying carrier. The siRNA conveying carrier provided by the invention has the physical and chemical properties of small particle size and suitable surface potential, has good siRNA compounding ability, low cell toxicity and high transfection rate, is a safe and efficient nano carrier with siRNA conveying function and has broad application prospect in siRNA conveying and disease treatment based on RNA interference.

The invention discloses application of superparamagnetic iron oxide nanoparticles in preparation of nerve magnetic stimulation enhancers for treating neurogenic diseases. On the basis of magnetic nanomaterials and the action of a magnetic field, method and system construction for magnetic stimulation of deep brain nerves are realized. The application has the advantages that the high compatibilityand magnetic field response characteristics of the superparamagnetic iron oxide nanoparticles are utilized to feed the superparamagnetic iron oxide nanoparticles to a specific brain region, the magnetic nanoparticles amplify the magnetic field effect under the action of a specific external magnetic field, surrounding nerve cells are stimulated, activation of neural circuits is realized, and accordingly, some neurogenic diseases can be treated.

The invention discloses a preparation method of a magnetic chitosan modified silk fabric. The preparation method comprises the following steps: dissolving chitosan in a beaker filled with distilled water, adding glacial acetic acid, putting the beaker in a magnetic stirrer, stirring until the chitosan is completely dissolved and the solution becomes transparent; adding ferric chloride into ethylene glycol, stirring until ferric chloride is completely dissolved and the solution becomes yellow and transparent, adding sodium acetate while stirring until the solution becomes thick and uniform brown yellow to obtain a ferric oxide solution; slowly adding the prepared chitosan solution into the magnetic nano iron oxide solution while stirring until the mixed solution slowly becomes transparent wine red to obtain a magnetic iron oxide chitosan hybrid solution; treating the silk fabric by using the solution on a constant-temperature oscillation dyeing machine, washing and drying to obtain thesilk fabric. The method is rapid and easy to operate, the surface roughness of the treated silk is increased, chitosan-coated magnetic iron oxide nano particles exist on the silk fabric, and adsorption of a natural dye namely anthocyanin is enhanced.

The invention relates to a magnetic iron oxide-graphene nano composite material for removing dye pollution of a water body as well as a preparation method and application of the magnetic iron oxide-graphene nano composite material. The preparation method comprises the following steps: dispersing graphene oxide into deionized water, adding the graphene oxide into a mixed solution of ferric chlorideand sodium citrate, fully mixing, regulating the pH value to 9-11, transferring into a reaction kettle, and carrying out hydrothermal reaction so as to obtain a gamma-Fe2O3@rGO nano composite material. Compared with the prior art, according to the gamma-Fe2O3@rGO nano composite material disclosed by the invention, gamma-Fe2O3 is uniformly distributed on the surface of the GO; and an interlayer composite structure formed by the gamma-Fe2O3 and the GO is beneficial to maintaining the stability of the material, and has the inherent characteristics of graphene and magnetic iron oxide nanoparticles, so that the composite material has a larger specific surface area and better adsorption performance, and has the necessity and feasibility of recycling.