11 results about "Superparamagnetic iron oxide nanoparticles" patented technology

The invention discloses a visual efficient chloride ion removal adsorbing material and a preparation method and application thereof.The adsorbing material is prepared by the steps that hollow glass microspheres serve as a carrier, and hollow glass porous particles are synthesized from a mixture of hollow glass microsphere powder and a pore forming agent through a sol-gel method; the preparation method comprises the following steps: modifying the surface of a porous adsorption material through a low-temperature plasma bombardment technology to enhance the adsorption performance on chloride ions, and loading magnetic iron oxide nanoparticles on the porous adsorption material to prepare the chloride ion adsorption material; the adsorption material has the characteristic of environmental friendliness, not only can efficiently adsorb chloride ions in a water body, but also can realize the visualization of the adsorption process through the density difference before and after adsorption, has the characteristics of repeated use and easiness in regeneration, and has relatively high market application prospect and economic value.

The application discloses a kind of multistage size response type iron-based nano preparation and its preparation method and application, the iron-based nano preparation includes responsive iron-based nanomaterial and the protein drug of load, the responsive iron-based nanomaterial is by magnetic iron oxide nanoparticles surface complex dopamine and dopamine phenylboronic acid ligand, the molar ratio of two ligands is 1:0.52~2.57;Preparation method: magnetic iron oxide nanoparticles is dispersed in solvent, dopamine hydrochloride and dopamine phenylboronic acid are added, and under the condition of 40~80 DEG C reaction, obtain responsive iron-based nanomaterial;Protein drug is mixed with the responsive iron-based nanomaterial obtained in aqueous solvent, and evenly dispersed to obtain target nano preparation.The multistage size response type iron-based nano preparation of the application realizes microenvironment response delivery, deep penetration, lysosome enrichment, efficient iron death trigger and the cascade synergistic effect of immune activation, provides a kind of safe and efficient new strategy for tumor synergistic treatment.

The present disclosure provides a method for separating iron element in brine and application thereof. The method for separating iron element in brine comprises: adding a pH adjusting agent to brine, to adjust pH of the brine to 6.0-7.0, and controlling the temperature of the brine to 75° C.-90° C.; introducing an oxygen-containing gas into the brine, to covert the iron element in the brine into magnetic iron oxide; and separating the magnetic iron oxide from the brine by magnetic adsorption to obtain an iron-removed brine.

The invention relates to the technical field of printing materials, in particular to high-stability carbon powder as well as a preparation method and application thereof. The carbon powder comprises the following components in parts by mass: 60-70 parts of modified styrene-acrylic resin, 10-12 parts of carbon black, 5-6 parts of a charge control agent, 5-6 parts of a silane coupling agent, 18-22 parts of magnetic iron oxide, 2-4 parts of a lubricant and 2-4 parts of a plasticizer, the carbon powder disclosed by the invention is good in stability under high-temperature and high-humidity storage conditions, the problems of caking, charge attenuation and image blurring are effectively prevented, and the carbon powder also has a relatively wide melting point range, so that the continuity of printing operation and the consistency of output quality are ensured.

Disclosed is a multi-functional nanoparticle delivery system comprising a biodegradable core of poly(lactic-co-glycolic acid) (PLGA) or calcium phosphate (CaP), encapsulating a nicotinamide adenine dinucleotide (NAD+) precursor and a sirtuin activator. Surrounding the core is a liposomal or polymeric layer containing one or more senolytic agents, and an outer layer of magnetic iron oxide nanoparticles for targeted delivery, external manipulation, and imaging. In some embodiments, the nanoparticle surface is functionalized for conjugation with autologous mesenchymal stem cells to enhance homing and regenerative potential. The system is pH-responsive, releasing its payload in acidic microenvironments typical of senescent or diseased cells, while remaining stable at physiological pH. This integrated design supports NAD+ restoration, sirtuin activation, senescent cell clearance, and tissue regeneration. Applications include treatment of age-related diseases, regenerative medicine, cardiovascular and neurodegenerative disorders, and cosmetic skin rejuvenation.

The present invention discloses a magnetic ferroferric oxide nanoparticle, and a preparation method therefor and the use thereof. The magnetic ferroferric oxide nanoparticle contains ferroferric oxide and a hydrophilic macromolecule, wherein the ferroferric oxide and the hydrophilic macromolecule are in at least one of the following relationships (1) and (2): (1) the hydrophilic macromolecule is adsorbed on the surface of the ferroferric oxide; and (2) the ferroferric oxide and the hydrophilic macromolecule are in the state of mutual embedding or occlusion. In the present invention, the hydrophilic macromolecule is used as a stabilizer, and ferrous ions and ferric ions form the magnetic ferroferric oxide nanoparticle by means of coprecipitation; and the magnetic ferroferric oxide nanoparticle has a relatively high longitudinal magnetic relaxation rate r1, a relatively low transverse / longitudinal magnetic relaxation rate ratio (r2 / r1), good water solubility, high stability, and good biocompatibility, and can be used as a contrast agent for T1-weighted magnetic resonance imaging (MRI) to improve the contrast and sensitivity of MRI.

The invention relates to the technical field of nondestructive testing, in particular to magnetic-fluorescent difunctional nanoparticles as well as a preparation method and application thereof. The preparation method provided by the invention comprises the following steps: dissolving ferric chloride hexahydrate and sodium salt in ethylene glycol, adding an amine compound and an emulsifier, uniformly mixing, heating for reaction, and cleaning and drying after the reaction is finished to obtain amino-modified magnetic iron oxide nanoparticles; the preparation method comprises the following steps: dispersing magnetic iron oxide nanoparticles in absolute ethyl alcohol, adding a polymer monomer, stirring, carrying out heating reaction, and carrying out magnetic separation, cleaning and drying after the reaction is ended, so as to obtain aminated magnetic iron oxide nanoparticles with an intermediate layer; dispersing the prepared nano-particles in absolute ethyl alcohol, adding a rare earth compound, a rare earth fluorescent complex and an amine compound, performing stirring reaction at room temperature, performing magnetic separation, cleaning and drying after the reaction, and performing post-treatment on the nano-particles to obtain the magnetic-fluorescent dual-function nano-particles.

The invention belongs to the technical field of raw material conveying, and discloses a feeding mechanism based on magnetic iron oxide black production, which comprises a base, a material collecting device fixedly mounted at the top of the base, and a recoverable feeding mechanism comprising a collecting mechanism movably clamped in the material collecting device. The top of the material collecting device is fixedly connected with a feeding device, and the top of the material collecting device is fixedly provided with an active feeding device. A moving block moves towards the feeding device on a rail, so that a spherical shell can push a push plate to move through a connecting rod and a fixed block, torsion springs installed on the connecting rod and the moving block can help the push plate to be close to the inner wall of a hopper all the time, scrap iron raw materials are fully pushed at a constant speed, and the problems that when the hopper is flatly laid, feeding is not uniform, and the feeding efficiency is high are solved. And therefore, fine scraps are accumulated on the two sides of the conveying crawler belt, and equipment is easy to damage.

The invention discloses a preparation method of PEG-DA modified magnetic iron oxide nanoparticles. The preparation method comprises the following steps: synthesis of small-size Fe2O3 nanoparticles: synthesizing the Fe2O3 nanoparticles by adopting a thermal decomposition method; and modifying the Fe2O3 nanoparticles with PEG-DA (Polyethylene Glycol The Fe2O3 nano-particles synthesized by adopting a thermal decomposition method are easy to control in shape and size, high in crystallinity, high in size controllability and smaller in aggregation trend, and the method is more advanced in synthesis of the iron oxide nano-particles with higher performance. PEG-DA (polyethylene glycol-dopamine) is adopted to modify the Fe2O3 nano-particles, so that the hydrophilicity can be increased, the biocompatibility can be improved, and the obtained Fe2O3-coated PEG-DA nano-particles are good in stability and good in T1 performance.

The application discloses a preparation method of PEG-DA modified magnetic iron oxide nanoparticles, and comprises the following steps: synthesizing small-size Fe2O3 nanoparticles by adopting a thermal decomposition method; and modifying the Fe2O3 nanoparticles by PEG-DA. The Fe2O3 nanoparticles synthesized by the thermal decomposition method are easy to control in shape and size, have high crystallinity, high controllability in size, and small aggregation trend, and the method is more advanced in synthesizing iron oxide nanoparticles with higher performance. The Fe2O3 nanoparticles modified by PEG-DA (polyethylene glycol-dopamine) can increase hydrophilicity and improve biocompatibility, and the obtained Fe2O3@PEG-DA nanoparticles are good in stability and have good T1 performance.

The application provides a method for separating iron elements in brine and application thereof, and the method for separating iron elements in brine comprises the following steps: adding a pH regulator into the brine, adjusting the pH value of the brine to 6.0-7.0, and controlling the temperature of the brine to be 75-90 DEG C; introducing oxygen-containing gas into the brine, so that the iron elements in the brine form magnetic iron oxide; and separating the magnetic iron oxide from the brine by using a magnetic separator to obtain iron-removed brine. The method can convert the iron elements in the brine into magnetic iron oxide, and then remove the iron elements from the brine by using a magnetic separation technology, so that the problem that iron ions in the brine interfere with the adsorption of lithium by an adsorbent is solved, and the iron-removed brine obtained by the method can be directly used for lithium extraction by an adsorption method, which is matched with the existing process conditions for lithium extraction from brine, and has good practicability.