Pharmaceutical composition for treating child viral myocarditis and application thereof

A technology of viral myocarditis and composition, which is applied in the field of pharmaceutical composition and its preparation for the treatment of viral myocarditis in children, can solve the problems of uncertain curative effect of viral myocarditis, and achieve the effect of improving cardiomyocyte metabolism and nourishing myocardium

Inactive Publication Date: 2015-09-16
QINGDAO JINZHI HIGH NEW TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine treatment mainly targets primary infection and myocardial inflammation, but the curative effect of existing antiviral drugs on viral myocarditis is uncertain, and traditional Chinese medicine shows obvious advantages in this regard

Method used

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  • Pharmaceutical composition for treating child viral myocarditis and application thereof
  • Pharmaceutical composition for treating child viral myocarditis and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Embodiment 1: the preparation of Chinese medicine extract

[0013] Weigh 0.16kg of Guizhi, 0.11kg of Nansha Ginseng, 0.11kg of Daqingye, 0.11kg of Rhizoma Cyperi, 0.11kg of Rehmannia Rehmanniae, 0.25kg of Zhigancao, 0.20kg of August Zha, 0.06kg of Dried Ginger, 0.06kg of Polygala, and 0.06kg of Sophora Sophorae kg, combined, placed in an extraction device with a round bottom flask, and extracted three times with an ethanol solution with a volume concentration of 80%, adding an ethanol solution 12 times the total amount of medicinal materials for the first time, and extracting for 2 hours; adding medicinal materials for the second time 11 times the total amount of ethanol solution, extract for 2 hours; thirdly add ethanol solution of 10 times the total amount of medicinal materials, extract for 1.5 hours; filter through four layers of gauze, combine the filtrate, concentrate under reduced pressure and recover ethanol to a thick paste, freeze-dry, Pulverize into fine powd...

Embodiment 2

[0014] Embodiment 2: the preparation of Chinese medicine extract

[0015] Weigh 0.25kg of cassia twig, 0.15kg of Nansha ginseng, 0.15kg of Daqingye, 0.13kg of Rhizoma Cyperi, 0.13kg of Rehmannia glutinosa, 0.20kg of Zhigancao, 20kg of August Zha, 9kg of dried ginger, 9kg of polygala, and 9kg of Sophora flavescens, and combine them. Put it in an extraction device with a round bottom flask, and use an ethanol solution with a volume concentration of 85% to reflux extract three times, add an ethanol solution 12 times the total amount of medicinal materials for the first time, and extract for 2 hours; add 11 times the total amount of medicinal materials for the second time The ethanol solution was extracted for 1.5 hours; for the third time, an ethanol solution 10 times the total amount of medicinal materials was added, and the extraction was performed for 1.5 hours; four layers of gauze were filtered, the filtrate was combined, concentrated under reduced pressure and ethanol was re...

Embodiment 3

[0016] Embodiment 3: the preparation of Chinese medicine extract

[0017] Weigh 2.1kg of Guizhi, 1.2kg of Nansha Ginseng, 1.2kg of Daqingye, 1.0kg of Rhizoma Cyperi, 1.2kg of Rehmannia glutinosa, 2.0kg of Zhigancao, 2.0kg of August Zha, 0.9kg of Dried Ginger, 0.9kg of Polygala, and 0.9kg of Sophora flavescens. kg, combined, placed in an extraction device with a round bottom flask, and extracted three times with an ethanol solution with a volume concentration of 80%, adding an ethanol solution 12 times the total amount of medicinal materials for the first time, and extracting for 2 hours; adding medicinal materials for the second time 11 times the total amount of ethanol solution, extract for 1.5 hours; thirdly add 10 times the total amount of medicinal materials, extract for 1.5 hours; filter through four layers of gauze, combine the filtrate, concentrate under reduced pressure and recover ethanol to a thick paste, freeze-dry , crushed into fine powder, and passed through a 10...

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Abstract

The invention discloses a pharmaceutical composition for treating child viral myocarditis and application thereof. The pharmaceutical composition is prepared from, by weight, traditional Chinese medicinal materials of 16-25 parts of cassia twig, 9-15 parts of adenophora tetraphylla, 9-15 parts of folium isatidis, 8-13 parts of rhizoma cyperi, 9-15 parts of radix rehmanniae preparata, 16-25 parts of honey-fried licorice roots, 16-25 parts of fiveleaf akebia fruit, 6-12 parts of dried ginger, 6-12 parts of polygala tenuifolia and 6-12 parts of radix sophorae flavescentis. According to the pharmaceutical composition, the common Chinese herbal medicine is used as the raw materials, so that production cost is low, and the pharmaceutical composition has good effects of improving cardiac muscle cell metabolism, nourishing cardiac muscles and promoting cardiac muscle recovery, and is suitable for being developed to medicine for treating child viral myocarditis.

Description

technical field [0001] The invention belongs to the technical field of extraction of traditional Chinese medicinal materials, and relates to a pharmaceutical composition for treating children with viral myocarditis, a preparation method and application thereof. Background technique [0002] Viral myocarditis can occur at any age, and it is more common in adolescents. The pathogenesis of the disease is not yet fully understood, but the direct lysis of cardiomyocytes by the virus and the autoimmune damage to myocardial tissue induced by the virus are important causes of viral myocarditis. Pathogenesis. Western medicine treatment mainly targets primary infection and myocardial inflammation, but the curative effect of existing antiviral drugs on viral myocarditis is uncertain, and traditional Chinese medicine shows obvious advantages in this respect. Contents of the invention [0003] The object of the present invention is to provide a kind of pharmaceutical composition and a...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P31/12A61P9/00
Inventor 不公告发明人
Owner QINGDAO JINZHI HIGH NEW TECH
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