Method for judging visceral lipopexia susceptibility

A visceral fat, susceptibility technology, applied in the determination/inspection of microorganisms, biochemical equipment and methods, DNA/RNA fragments, etc., can solve problems such as obesity

Active Publication Date: 2015-09-30
KAO CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

That is, most of the causes of obesity are living habits or eating habits, but even if they have the same living habits or eating habits, people with obesity genes are more likely to be obese

Method used

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  • Method for judging visceral lipopexia susceptibility
  • Method for judging visceral lipopexia susceptibility
  • Method for judging visceral lipopexia susceptibility

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0218] (1) Identification of susceptibility SNPs for visceral fat accumulation

[0219] In the Health Diagnosis Center of the Affiliated Hospital of Jiji Medical University, informed consent was given to 3013 people who were diagnosed in the General Health Examination Center, and 2222 people who obtained consent to use in this study were tested for SNP of GIP gene or GIPR gene, visceral fat area, Gene correlation analysis of abdominal circumference and BMI. Subjects are shown in Table 2. The visceral fat area of ​​each subject was measured using a visceral fat meter (DIABETES CARE, 28:451-453, 2005) based on an impedance method confirmed to show a strong correlation with computed tomography (CT) analysis. In addition, the abdominal diameter, height, and weight of each subject were measured, and BMI was calculated.

[0220] Table 2

[0221] Summary of objects

[0222]

[0223] Items other than the number of people represent average values ​​(standard errors).

[0224] L...

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Abstract

The invention relates to a method for judging visceral lipopexia susceptibility. According to the method, the type of SNP represented by dbSNP:IDrs9904288 contained in a DNA sample acquired from a testee is taken as an index to judge the susceptibility of genetic predisposition of visceral lipopexia, dangerousness of increase of visceral fat, dangerousness of attack or development of disease or state caused by visceral lipopexia of the testee.

Description

technical field [0001] The present invention relates to determination of human susceptibility to visceral fat accumulation using genes associated with human visceral fat accumulation. Background technique [0002] There are various causes of obesity, and many of them are considered to be brought about by living habits or eating habits. For example, high-calorie foods brought about by Westernized eating habits, irregular meal times and eating methods, fasting, eating too fast, late dinner, or lack of exercise contribute to obesity. Obesity is closely related to lifestyle-related diseases such as diabetes, hypertension, and dyslipidemia, and metabolic syndrome. Obesity causes or worsens metabolic syndrome and lifestyle-related diseases, and these diseases cause blood vessels to be damaged and become fragile, causing arteriosclerosis, resulting in serious diseases such as myocardial infarction and cerebral hemorrhage. [0003] As an indicator of obesity, body mass index (BMI:...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12Q1/68C12N15/11
CPCC12Q1/6883C12Q2600/156
Inventor 大崎纪子下丰留玲岩本祯彦中山一大
Owner KAO CORP
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