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A compound preparation for whitening and removing freckles and its preparation method

A freckle compound and whitening technology, which is applied in the field of compound preparations, whitening and anti-freckle compound preparations and their preparations, can solve the problems of discoloration, taste, irritation and side effects of preparations, and achieve inhibition of melanin synthesis, repair of skin barriers, and improvement of blood vessels. effect of factors

Active Publication Date: 2018-05-18
YUNNAN BOTANEE BIO TECH GRP CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the commonly used external preparations mainly solve the problem of pigmentation by inhibiting tyrosinase activity and melanocyte activity. The use of such products has certain potential risks and needs to be used under the guidance of a doctor; the milder active ingredients include azelaic acid, arbutin, vitamin C, etc., such preparations have problems such as the solubility of raw materials The preparation process is inconvenient, or the raw materials themselves are easily oxidized, and there will be unstable phenomena such as discoloration and odor of the preparation
[0004] In addition, pigmented dermatosis is a multi-inducing disease, and improving tyrosinase and melanocytes alone cannot achieve long-term treatment or alleviation of symptoms

Method used

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  • A compound preparation for whitening and removing freckles and its preparation method
  • A compound preparation for whitening and removing freckles and its preparation method
  • A compound preparation for whitening and removing freckles and its preparation method

Examples

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Effect test

Embodiment 5

[0059] The whitening and freckle-removing compound preparation of Example 5 was used as the experimental group and a certain commercially available whitening and freckle-removing product B was used as the control group for long-term trials. The number of testers is 30 people, equally divided into the experimental group and the control group, one course of treatment is 28 days, and the evaluation will be carried out after the two courses of treatment.

[0060] The whitening and freckle-removing compound preparation of Example 5 was evenly applied to the faces of the experimental group, and a commercially available whitening and freckle-removing product B was evenly applied to the faces of the control group, both twice a day for 28 consecutive days. , 14 days after use, and 28 days after use, the skin lesion recovery of the subjects, and the satisfaction and safety of the product were evaluated by the subjects.

[0061] Test population: 30 subjects, 1 male and 29 females, includ...

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PUM

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Abstract

The invention discloses a whitening and freckle-removing composite preparation which comprises the following components: deionized water, sucrose stearate, glycerol, butanediol, N-methyl pyrrolidone, carbomer, phenoxyethanol, glyceryl stearate, polydimethylsiloxane, squalane, butyrospermum parkii, phytosterol hydroxystearate, a pepper extract, seed oil of prinsepia utilis, a camellia reticulata tea extract, a folium artemisiae argyi extract, a horse chestnut extract, tetrahydrocurcumin, glutathione, azelaic acid and xanthan gum. The whitening and freckle-removing composite preparation disclosed by the invention is mainly designed from four whitening and freckle-removing mechanisms of melanin synthesis inhibition, skin barrier remediation, blood vessel factor improvement and inflammation prevention and has the functions of whitening the skin, removing freckles and beautifying the face. The invention further discloses a preparation method of the whitening and freckle-removing composite preparation. The problem of dissolving azelaic acid is solved by using a special process, and thus the stability of the product is improved.

Description

technical field [0001] The invention relates to a compound preparation, in particular to a whitening and freckle-removing compound preparation and a preparation method thereof, which are suitable for the fields of medicine and personal care. Background technique [0002] As we all know, pigmentation disorders such as chloasma, freckles, and hyperpigmentation have been troubling people, especially melasma (chloasma), which is a pigmentation disorder that occurs in young and middle-aged women. , manifested as symmetrical yellowish-brown patches on the face, among which the most common occurrence is the symmetrical appearance of the cheeks on both sides. It is shaped like a butterfly, also known as butterfly spots. , and can cause endocrine disorders and nervous system disorders, so the disease is closely related to the entire functional state of the human body, bringing dual effects on the patient's mind and body. [0003] At present, the commonly used external preparations m...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61K8/64A61K8/49A61K8/362A61K8/35A61Q19/02A61Q19/00
Inventor 苏温柔马骁王飞飞高绍阳郭振宇何黎
Owner YUNNAN BOTANEE BIO TECH GRP CO LTD
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