Freckle-removing and beautifying composition containing fish maw oligopeptide as well as preparation method and application of freckle-removing and beautifying composition

A cosmetic composition and oligopeptide technology are applied in the field of freckle-removing cosmetic compositions and their preparation, which can solve the problems that the application of freckle-removing cosmetic formulations has not been reported, and achieve the effects of being easy to obtain, small in molecular weight and high in activity

Active Publication Date: 2022-03-08
DALIAN SHENLAN PEPTIDE TECH R & D CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Fish gum protein can be hydrolyzed with different proteases to obtain a variety of active peptides. At present, there are researches on the preparation and application of fish gum peptides, such as CN201710907667.3 A preparation method of fish gum peptides, CN201810406679.2 A fish gum for postpartum conditioning Elastin peptide composition and its preparation method, but there is no report on the research on the specific active peptide segment of flower maw peptide and the application of freckle-removing beauty prescription

Method used

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  • Freckle-removing and beautifying composition containing fish maw oligopeptide as well as preparation method and application of freckle-removing and beautifying composition
  • Freckle-removing and beautifying composition containing fish maw oligopeptide as well as preparation method and application of freckle-removing and beautifying composition
  • Freckle-removing and beautifying composition containing fish maw oligopeptide as well as preparation method and application of freckle-removing and beautifying composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] A method for separating and purifying fish maw oligopeptides containing tyrosinase inhibitory active peptides in a freckle-removing beauty composition containing fish maw oligopeptides, comprising the following steps:

[0039] (1) After the fish maw is treated, add 20 times the mass volume of water to make a homogenate and place it in an enzymolysis tank, then add a compound protease with 4% of the fish maw protein mass, and enzymolyze it at 50°C for 4 hours, and the pH of the enzyme reaction The value is controlled at 7.5. After the enzymolysis is completed, the temperature is raised to 90°C to inactivate the enzyme for 10 minutes to obtain the enzymatic hydrolyzate of fish maw protein. Centrifuge the enzymatic hydrolyzate at 8000 rpm for 10 minutes to remove particulate matter, and then use membrane separation technology for separation. The molecular weight cut-off is 3000Da, and the membrane liquid is spray-dried to obtain fish maw oligopeptide powder; the mass ratio ...

Embodiment 2

[0054] A freckle-removing beauty composition containing fish maw oligopeptides, the components of which are 90 parts of fish maw oligopeptide powder, 30 parts of angelica powder, 40 parts of peach kernel powder, 25 parts of sea cucumber oligopeptide powder, 50 parts of wolfberry powder, poria cocos 30 parts of yam powder, 40 parts of yam powder, 40 parts of wild jujube kernel powder, and 30 parts of rose powder.

[0055] The preparation method is:

[0056] (1) The preparation method of fish maw oligopeptide: after the fish maw is treated, add 18 times the mass volume of water to make a homogenate and place it in an enzymolysis tank, then add a compound protease with 3% of the fish maw protein quality, and heat it at 52°C The enzymatic hydrolysis was carried out for 5 hours, and the pH value of the enzyme reaction was controlled at 7.0. After the enzymatic hydrolysis, the temperature was raised to 85°C to inactivate the enzyme for 10 minutes to obtain the enzymatic hydrolyzate ...

Embodiment 3

[0061] A freckle-removing cosmetic composition containing fish maw oligopeptide, the components of which are 70 parts of fish maw oligopeptide powder, 28 parts of angelica powder, 35 parts of peach kernel powder, 20 parts of sea cucumber oligopeptide powder, 40 parts of wolfberry powder, poria cocos 25 parts of yam powder, 30 parts of yam powder, 35 parts of wild jujube kernel powder, and 20 parts of rose powder.

[0062] The preparation method is:

[0063] (1) The preparation method of fish maw oligopeptide powder: after the fish maw is treated, add 16 times the mass volume of water to make a homogenate and place it in an enzymolysis tank, then add a compound protease with 5% of the protein quality of the fish maw, at 55 Enzymolysis at ℃ for 3 hours, the pH value of the enzyme reaction was controlled at 8.0, after the end of the enzymolysis, the temperature was raised to 80℃ to inactivate the enzyme for 10 minutes to obtain the enzymatic hydrolyzate of fish maw protein, and t...

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Abstract

The invention relates to a freckle-removing and beautifying composition containing fish maw oligopeptide and a preparation method and application thereof, and belongs to the field of food, the freckle-removing and beautifying composition comprises fish maw oligopeptide powder, Chinese angelica powder, peach kernel powder, sea cucumber oligopeptide powder, Chinese wolfberry powder, poria cocos powder, Chinese yam powder, spina date seed powder, rose, grape seed extract and vitamin E. Under the synergistic effect of the components in the formula, the freckle-removing and beautifying cream has good freckle-removing and beautifying effects.

Description

technical field [0001] The invention belongs to the field of food, and in particular relates to a freckle-removing beauty composition containing fish maw oligopeptide and a preparation method thereof. Background technique [0002] The largest organ of the human body is the skin, and the difference in skin color mainly depends on the melanin synthesized by epidermal melanocytes. Pigmentation is usually a skin problem or disease caused by melanin, common such as melasma and freckles, is a global problem. According to the survey, there are more than 5 million people with chloasma in the United States alone, and the number of patients in China is also increasing year by year. [0003] The formation of skin spots is related to many factors, such as genetic factors, skin antioxidant system imbalance, endocrine disorders (thyroid hormone, sex hormone abnormalities), vascular factors, irregular menstruation, oral contraceptives, pregnancy, nutrient abnormalities, light damage, Men...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/64A61K8/9728A61K8/9789A23L19/00A23L19/10A23L25/00A23L31/00A23L33/10A23L33/18A61K38/08A61P17/16A61P19/00A61P19/02C12P21/06C07K1/34C07K7/06C07K1/16
CPCC12P21/06C07K1/34C07K7/06A61K8/64A61K8/9789A61K8/9728A61K38/08A61K38/012A61K36/232A61K36/736A61K36/815A61K36/076A61K36/8945A61K36/725A61K36/738A61P17/16A61P19/00A61P19/02A23L33/18A23L33/10A23L25/30A23L19/01A23L19/10A23L31/00A61K2800/782A61K2800/805A23V2002/00A61K2300/00A23V2250/55A23V2200/318A23V2200/326A23V2200/30
Inventor 张延胜包卫洋王祖哲高威郑远迪
Owner DALIAN SHENLAN PEPTIDE TECH R & D CO LTD
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