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Pharmaceutical composition containing calycosin and pharmaceutical application thereof

A technology of calycosin and composition, applied in the field of medicine

Inactive Publication Date: 2015-10-28
XIAN SHIJISHENGKANG PHARMA IND
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, there are many research reports on the therapeutic effects of the above three components at home and abroad, and the treatment field is wide, but there is no report on the combination of two or two components with a fixed dosage for the treatment of kidney and other diseases.

Method used

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  • Pharmaceutical composition containing calycosin and pharmaceutical application thereof
  • Pharmaceutical composition containing calycosin and pharmaceutical application thereof
  • Pharmaceutical composition containing calycosin and pharmaceutical application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0126] Take 0.3g of calycosin and 0.05g of astragaloside IV, add PEG-20050ml, add water for injection to dilute to 500ml, filter, add water for injection to 800ml, adjust the pH value to 6.5-7.0, add water for injection to dilute to 1000ml, and use Filter through a 0.22 μm microporous membrane, aliquot and sterilize to obtain an injection.

Embodiment 2

[0128] Take 0.6g of calycosin and 1g of astragalus polysaccharide, add PEG-20050ml, add water for injection to dilute to 500ml, filter, add water for injection to 800ml, adjust the pH value to 6.5-7.0, add water for injection to dilute to 1000ml, and use 0.22μm Filter through a microporous membrane, subpackage, and sterilize to obtain an injection.

Embodiment 3

[0130] Take 0.5g of calycosin, 2g of astragalus polysaccharide, 0.05g of astragaloside, add PEG-20050ml, add water for injection to dilute to 500ml, filter, add water for injection to 800ml, adjust the pH value to 6.5-7.0, add water for injection to dilute to 1000ml, filtered through a 0.22μm microporous membrane, subpackaged, and sterilized to obtain an injection.

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Abstract

The invention relates to a pharmaceutical composition containing calycosin and a pharmaceutical application thereof. The composition contains calycosin, astragaloside and / or astragalus polysaccharide. The composition can be made into a solid, liquid, gaseous or semisolid preparation. Lots of experiments confirm that the pharmaceutical composition can be used in treating kidney disease, chronic renal failure, nephritis, hypertensive nephropathy, cardiovascular and cerebrovascular diseases and tumor diseases, etc.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a pharmaceutical composition containing calycosin and its pharmaceutical application. Background technique [0002] Astragalus is one of the commonly used traditional Chinese medicines. It has the functions of invigorating the middle and replenishing qi, diuresis, evacuating pus, astringing sores and promoting granulation. Not sure. Therefore, it is necessary to study and analyze its main components to clarify the mechanism of action. [0003] Calycosin is one of the flavonoids in Astragalus with high content. Studies have shown that it can improve immune function, protect cardiovascular and cerebrovascular, liver, kidney and lung, and can also lower blood fat, blood sugar, and diabetes complications. [0004] Modern research has found that astragaloside IV is one of the main active ingredients of Astragalus membranaceus, which has various pharmacological effects such as ant...

Claims

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Application Information

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IPC IPC(8): A61K31/715A61K31/7048A61P13/12A61P29/00A61P35/00A61P9/00A61K31/352
Inventor 吴芳吕延英王光建赵兴詹芳王俊平贾诚曾艳龙
Owner XIAN SHIJISHENGKANG PHARMA IND
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