Adjuvant imaging traditional Chinese medicine preparation for ultrasonic examination and preparation method of preparation

A traditional Chinese medicine preparation and auxiliary imaging technology, applied in the direction of echo/ultrasound imaging agent, etc., can solve the problems of poor diagnostic accuracy of gastrointestinal diseases, failure to adopt gastrointestinal diseases, and delayed treatment timing, etc., to improve the accuracy of inspection, non-toxic Effect of side effects and low cost

Inactive Publication Date: 2015-12-02
孙凤香
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  • Abstract
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  • Claims
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AI Technical Summary

Problems solved by technology

[0003] At present, the clinical diagnosis of many gastrointestinal diseases mainly relies on X-ray barium meal examination and gastroscopy examination, such as gastric ulcer and duodenal ulcer, etc., but these two examinations are both painful and painful, and have certain limitations. Universal examination, especially for children, pregnant women, the elderly and the infirm, is not easy to accept, and it is also difficult for asymptomatic people, leading to some misdiagnosis and mistreatment, and even gastrointestinal perforation or bleeding before diagnosis and treatment, delaying the timing of treatment
Although B-ultrasound has the advantages of simplicity, safety, non-invasiveness, and painlessness, it has not been adopted by more gastrointestinal diseases due to its poor diagnostic accuracy for some gastrointestinal diseases.

Method used

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  • Adjuvant imaging traditional Chinese medicine preparation for ultrasonic examination and preparation method of preparation

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preparation example Construction

[0042] When the prepared dosage form is a granule, its preparation method comprises the following steps:

[0043] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration of 85% to 95% relative to the mixture 4 to 8 times, heat to boiling and reflux for 3 to 5 hours, filter, and use the reflux liquid as a solvent , using the filter residue as the solute, use the percolation method to slowly percolate at a rate of 1-2ml per minute, collect the percolation liquid, and then concentrate it under reduced pressure at a vacuum of 0.06-0.09Mpa to 50-60°C with a relative density of 1.04 ~1.10 paste, spray drying, the air inlet temperature of the spray dryer is 160~175℃, and the air outlet temperature is 80~85℃, and then crushed into powder to make dry paste powder;

[0044] Step 2: Add 0.2-0.4 times of sucrose powder and 0.1-0.2 times of dextrin to the obtained dry cream powder to form granules, and dry at 40-50°C to obtain granul...

Embodiment 1

[0050] Embodiment 1: Granules

[0051] Take 80g of coriander seeds, 240g of rose leaves, 160g of Cyperus cyperi, 160g of evodia fruit, 120g of ground eggplant, 300g of bitter grass, 250g of vitex leaves, 210g of radish root, 150g of calamus, 250g of albizia bark, 160g of fish brain stone, red back 250g of sour vine, 180g of Bauhinia fruit, 170g of winter melon seeds, 220g of cattail husk, 160g of primrose root, 80g of pisanthin and 180g of jasmine;

[0052] Its preparation method comprises the following steps:

[0053] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration 6 times that of the mixture and 90% ethanol, heat to boiling and reflux for 4 hours, filter, use the reflux liquid as the solvent, and use the filter residue as the solute. The percolation method slowly percolates at a rate of 1ml per minute, collects the percolation liquid, and then concentrates it under reduced pressure at a vacuum of 0.08Mpa to a ...

Embodiment 2

[0055] Embodiment 2: tablet

[0056]Take 120g of coriander seeds, 220g of rose leaves, 180g of Cyperus cyperi, 140g of evocarpia, 130g of ground eggplant, 260g of bitter grass, 260g of vitex leaves, 190g of radish root, 170g of calamus, 220g of acacia bark, 200g of fish brain stone, and red back 220g of sour vine, 220g of Bauhinia fruit, 140g of winter melon seeds, 240g of cattail husk, 140g of primrose root, 110g of pisanthin and 160g of jasmine;

[0057] Its preparation method comprises the following steps:

[0058] The first step is to mix the raw materials of the traditional Chinese medicine preparation in proportion, add ethanol with an alcohol concentration of 85% that is 3 times the mass of the mixture, heat and reflux for 2 hours, extract, and filter to obtain the first extract; Add ethanol with an alcohol concentration of 95% to the dregs, which is twice the mass of the dregs, heat and reflux for 2 hours, extract, and filter to obtain the second extract; combine the ...

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Abstract

The invention provides an adjuvant imaging traditional Chinese medicine preparation for ultrasonic examination and a preparation method of the preparation. The preparation is prepared from the following medicinal raw mateirals: coriander seed, rose leaves, latifolious rush rhizome, euodia trichotoma fruit, pratia fruit, vallisneria spiralis, hempleaf negundo chastetree leaf, radix lindera reflexa, rhizoma acori graminei, cortex albiziae, otolithum sciaenae, pinkflower ecdysanthera root and leaf, Chinese redbud fruit, Chinese waxgourd seed, sweet gourd rind, siebold primrose root and rhizome, daghestan sweetclover herb and arabian jasmine flower. The adjuvant imaging traditional Chinese medicine preparation has the beneficial effects of low cost, convenience in use, safety and no toxic or side effect, can be used for improving the proportion of excellent imaging and improving the examination accuracy, and is capable of inspecting more gastrointestinal diseases by B-mode ultrasound. The preparation provides powerful basis for clinical diagnosis, and the preparation process is simple and practical.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine engineering, in particular to a traditional Chinese medicine preparation assisted by ultrasonic examination and a preparation method thereof. Background technique [0002] Ultrasound image diagnosis is one of the important diagnostic methods in medicine. Ultrasound has three major effects on matter: one is mechanical action, because the ultrasonic energy is huge, it often makes the material particles vibrate at high frequency mechanically, thus producing crushing, agglomeration, and stirring effects. The second is the thermal effect. When the ultrasonic wave acts on the substance, its energy is absorbed by the substance, thus increasing the temperature of the substance. The third is cavitation. When the ultrasonic wave acts on the liquid, the area with weak internal stress in the liquid (such as microscopic bubbles, etc.) becomes sparse due to the huge change in the sound pre...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K49/22
Inventor 孙凤香姜永杰李嘉伟张娜刘佳
Owner 孙凤香
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