Tibetan medicine ash bark bone setting cataplasm and preparation method thereof
A technology of skin bonding and ointment, which is applied in the field of medicine, can solve the problems of air bubbles affecting the quality, failure to form, and low peel strength, etc., and achieve the effect of less air bubbles, less air bubbles, and good adhesion
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experiment example 1
[0044] Experimental example 1 Study on the molding process of Babu ointment
[0045] Experiments have found that the medicinal material of Qinpi and Bone Bone is completely crushed into fine powder for feeding, or it is extracted with conventional water or ethanol, and then prepared into catarrh, but the results are not ideal, and the catarrh cannot be formed well.
[0046] 1) Prepare Pabu ointment by pulverizing the medicinal materials of Qin Pi and Bone Bone
[0047] Take the prescription medicinal materials of Qinpi bone joint, crush them and pass through a 180-mesh sieve, and select the base of the babu ointment such as gelatin, sodium hydroxymethyl cellulose, sodium polyacrylate, polyvinyl alcohol, propylene glycol, glycerin, micro-powdered silica gel, kaolin, polyethylene glycol One or several of the 400 and other matrices are prepared and mixed with pulverized prescription medicinal materials to prepare Pabu ointment. As a result, the obtained sample cannot be molded, o...
experiment example 2
[0053] Experimental example 2 Babu ointment base optimization test
[0054] On the basis of single factor investigation, the amount of water added in each step remains unchanged, the amount of azone is fixed at 20g, the amount of ethyl paraben is fixed at 2g, the extract is fixed at 10g, the fritillaria is fixed at 5g, and the keel is fixed at 5g. Intensity was used as an index, and the dosage and ratio of sodium carboxymethylcellulose, gelatin, glycerin, and sodium polyacrylate in the prescription were optimized by using an orthogonal design. 9 (3 4 ) orthogonal table to test, the factor level table is shown in Table 3
[0055] Table 1 Orthogonal design investigation factor level table
[0056]
[0057] Table 2 Babu ointment base optimization experiment results
[0058]
[0059] Table 3 Orthogonal test analysis of variance table
[0060]
[0061] According to the results of the orthogonal test, the influence order of the four factors on the peeling strength of th...
experiment example 3
[0063] Experimental example 3 optimizes the preparation process of babu ointment and reduces the generation of air bubbles
[0064] (1) Preparation of the extracts of Qinpi and Western Sichuan Feverfew: take the prescription amount of Qinpi and Western Sichuan Feverfew, add 70% ethanol to extract twice, add 70% ethanol of 10 times the amount of medicinal materials for the first time, decoct for 2 hours, the second Add 8 times the amount of 70% ethanol each time, decoct for 2 hours, combine the extracts, filter, concentrate under reduced pressure at 65°C to form a dry paste, and set aside;
[0065] (2) Take an appropriate amount of sodium carboxymethyl cellulose, an appropriate amount of sodium polyacrylate, 100g of glycerin, stir well, add 700g of water, and keep stirring in a water bath at 50°C;
[0066] (3) Take 20g of gelatin, add 300g of water, and swell in a water bath at 50°C for later use;
[0067] (4) Get 2g of ethylparaben, add dehydrated alcohol 18g to dissolve, get...
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