Methods of failsafing electrochemical measurements of an analyte as well as devices, apparatuses and systems incorporating the same

Abstract

Methods are disclosed for measuring an analyte concentration in a fluidic sample. Such methods further allow one to provide an error code or correct and / or compensate for interferents such as an antioxidant before providing an analyte concentration. The measurement methods utilize information obtained from test sequences having at least one DC block, where DC block includes at least one recovery potential, and where a closed circuit condition of the electrode system is maintained during the DC block. The methods use information relating to status of a redox mediator during the electrochemical analysis to provide a statistical antioxidant failsafe using either a classifier or a discriminator to determine whether the antioxidant is interfering with the analyte concentration. Also disclosed are devices, apparatuses and systems incorporating the various measurement methods.

Description

[0001] Cross References to Related Applications [0002] This patent application claims the benefit of US Provisional Patent Application No. 61 / 793,377, filed March 15, 2013, which is incorporated herein by reference as if set forth in its entirety. technical field [0003] The present disclosure relates generally to mathematics and medicine, and more particularly to methods for electrochemically measuring analytes in liquid samples and providing antioxidant fail-safe and / or reagent health fail-safe methods that prevent interference due to antioxidants and False reporting of falsely elevated analyte concentrations due to / or reagent failure, and the method even corrects for analyte concentrations. Background technique [0004] Significant benefits can be realized from the electrochemical measurement of analytes in liquid samples (ie, biological or environmental). For example, diabetes treatment using self-monitoring blood glucose (SMBG) devices and systems can help improve g...

AI Technical Summary

Problems solved by technology

[0006] Current electrochemical SMBG methods, devices, and systems offer advantages regarding convenience to individuals with diabetes; however, there is an added quality to checking electrochemically measuring the presence of interfering substances such as antioxidants in liquid samples There remains a need for improved methods for detecting failure of analytes or biosensor reagent systems

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