Method for preparing traditional Chinese medicine composition for treating cervical spondylosis
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A composition and technology for cervical spondylosis, applied in drug combinations, medical formulas, bone diseases, etc., can solve the problems of complex ingredients and increased cost of traditional Chinese medicine compositions, and achieve good curative effect, significant hemorheology parameters, and stable drug efficacy Effect
Inactive Publication Date: 2016-03-02
杨献美
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The Chinese medicine composition of the invention has more than 30 kinds of prescriptions, and the ingredients are very complex; and it contains many famous and precious Chinese herbal medicines such as Baishouwu and Ephedra, which greatly increases the cost of the Chinese medicine composition
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Embodiment 1
[0042] Example 1 of the present invention, the traditional Chinese medicine composition capsule is prepared from the following medicinal materials in parts by weight: 10 parts of Radix Ophiopogon japonicus, 8 parts of Schizonepeta, 10 parts of Shenjincao, 8 parts of Ma'an Teng, 8 parts of Notopterygium, 8 parts of Panax notoginseng, 6 parts of Eucommia ulmoides, 8 parts of Chuanxiong, 6 parts of Alisma, 4 parts of tangerine peel and 2 parts of licorice.
[0043] The preparation method is as follows:
[0044] (1): Take Ophiopogon japonicus, wash, dry, crush, pass through a 70-mesh sieve, place the obtained coarse powder in a supercritical carbon dioxide extraction device, add 40% of the weight of the coarse powder to ethanol with a volume fraction of 80%, and control carbon dioxide The flow rate is 18L / h, the extraction pressure is 20MPa, the extraction temperature is 50°C, the extraction time is 2h, and the Ophiopogon japonicus extract is obtained by separation under reduced p...
Embodiment 2
[0051] Example 2 of the present invention, the traditional Chinese medicine composition capsule is prepared from the following medicinal materials in parts by weight: 20 parts of Ophiopogon japonicus, 20 parts of Nepeta chinensis, 20 parts of Shenjincao, 18 parts of Maan vine, 16 parts of Notopterygium, 16 parts of Panax notoginseng, 14 parts of Eucommia ulmoides, 14 parts of Chuanxiong, 14 parts of Alisma, 8 parts of tangerine peel and 8 parts of licorice.
[0052] The preparation method is the same as in Example 1.
Embodiment 3
[0054] The traditional Chinese medicine composition capsule of Example 3 of the present invention is prepared from the following medicinal materials in parts by weight: 15 parts of Ophiopogon japonicus, 14 parts of Schizonepeta, 14 parts of Shenjincao, 14 parts of Echinacea, 12 parts of Notopterygium, 12 parts of Panax notoginseng, 10 parts of Eucommia ulmoides, 10 parts of Chuanxiong, 10 parts of Alisma, 6 parts of tangerine peel and 5 parts of licorice.
[0055] The preparation method is the same as in Example 1.
[0056] Pharmacodynamic studies:
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Abstract
The invention discloses a method for preparing a traditional Chinese medicine composition for treating cervical spondylosis, and belongs to the technical field of traditional Chinese medicine. The method comprises the following steps of washing Radix Ophiopogonis, pulverizing after drying and extracting to obtain a Radix Ophiopogonis extract; pulverizing herba schizonepetae, lycopodium clavatum, ipomoea pes caprae, Rhizoma seu Radix Notopterygii, pseudo-ginseng, eucommia, Ligusticum wallichii, rhizoma alismatis, pericarpium citri reticulatae and liquorice into coarse powder; merging Radix Ophiopogonis residues; concentrating to obtain an aqueous extract concentrated solution; carrying out alcohol extraction on the residues to obtain an alcohol extraction concentrated solution; and finally merging and evenly mixing the Radix Ophiopogonis extract, the aqueous extract concentrated solution and the alcohol extraction concentrated solution; and drying to obtain the traditional Chinese medicine composition. Raw materials of the traditional Chinese medicine composition prepared by the invention are easy to obtain, the composition is reasonable, a preparation technology is simple, and an animal test and clinical experiment prove that the traditional Chinese medicine component prepared by the invention has a remarkable curative effect on treatment of the cervical spondylosis, is small in toxic and side effects, can stimulate channels and promote qi and blood, and has good health-care and treatment effects on the cervical spondylosis.
Description
technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and relates to a method for preparing a traditional Chinese medicine composition for treating cervical spondylosis. Background technique [0002] Cervical spondylosis is a degenerative disease, which refers to the progressive degeneration of a single or multiple cervical intervertebral discs, and leads to structural changes in the surrounding bone and soft tissues, which in turn affects the related blood vessels, nerve roots or (and) the spinal cord. comorbidities. Cervical disc degeneration is the root cause of the occurrence and development of cervical spondylosis, dynamic and static imbalance of cervical spondylosis [0003] The animal model destroys the muscles and ligaments at the back of the neck, causing the static and dynamic system to lose its original balance, resulting in the degeneration of the cervical intervertebral disc. In the occurrence and development of ...
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