A kind of medical glue for minor outpatient surgery incision and its preparation method

A small surgery, incision technology, applied in the field of medical glue, can solve the problem of slow coagulation, achieve the effect of small coagulation speed, good glue properties, and promote anti-inflammatory healing without leaving scars

Active Publication Date: 2018-09-28
贵州通济智医科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, at present, medical glue is limited due to the limitation of raw materials and slow solidification during use.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] A medical glue for small outpatient surgical incisions, comprising raw materials of the following weight (kg): aloe protein 3, yam protein 3, soluble ginkgo polysaccharide 7, casein 1, polyoxyethylene aqueous solution 12, hydrogenated camellia oil 12, a- Cyanoacrylate 4, polyvinyl alcohol 14, ethylene / vinyl acetate copolymer 13, chitosan 3, polyaldehyde sodium alginate 6, pectin 3, gelatin 3.

[0016] A preparation method of medical glue for small outpatient surgery incision, including the following steps:

[0017] (1) Heat the polyoxyethylene aqueous solution to 53.5°C, and then mix and stir the aloe protein, yam protein, soluble ginkgo polysaccharide, casein, and polyoxyethylene aqueous solution for 20-30 minutes, and obtain the mixed solution for later use; heat the hydrogenated camellia oil to 185°C, then cool to 105°C and add it to the mixed solution, stir for 17.5 minutes until uniform, and obtain a functional mixed solution for use;

[0018] (2) Mix polyvinyl alcohol a...

Embodiment 2

[0021] A medical glue for small outpatient surgery incisions, comprising the following weight (kg) of raw materials: aloe protein 4, yam protein 4, soluble ginkgo polysaccharide 4, casein 4, polyethylene oxide aqueous solution 13.5, hydrogenated camellia oil 12.5, a- Cyanoacrylate 4, polyvinyl alcohol 13, ethylene / vinyl acetate copolymer 11.5, chitosan 2.5, polyaldehyde sodium alginate 5, pectin 1.5, gelatin 1.5.

[0022] A preparation method of medical glue for small outpatient surgery incision, including the following steps:

[0023] (1) Heat the polyoxyethylene aqueous solution to 53.5°C, and then mix and stir the aloe protein, yam protein, soluble ginkgo polysaccharide, casein, and polyoxyethylene aqueous solution for 20-30 minutes, and obtain the mixed solution for later use; heat the hydrogenated camellia oil to 185°C, then cool to 105°C and add it to the mixed solution, stir for 17.5 minutes until uniform, and obtain a functional mixed solution for use;

[0024] (2) Mix polyv...

Embodiment 3

[0027] A medical adhesive for small outpatient surgical incisions, comprising the following weight (kg) of raw materials: aloe protein 5, yam protein 5, soluble ginkgo polysaccharide 9, casein 3, polyethylene oxide aqueous solution 15, hydrogenated camellia oil 13, a- Cyanoacrylate 4, polyvinyl alcohol 12, ethylene / vinyl acetate copolymer 10, chitosan 2, polyaldehyde sodium alginate 4, pectin 1, gelatin 1.

[0028] A preparation method of medical glue for small outpatient surgery incision, including the following steps:

[0029] (1) Heat the polyoxyethylene aqueous solution to 53.5°C, and then mix and stir the aloe protein, yam protein, soluble ginkgo polysaccharide, casein, and polyoxyethylene aqueous solution for 20-30 minutes, and obtain the mixed solution for later use; heat the hydrogenated camellia oil to 185°C, then cool to 105°C and add it to the mixed solution, stir for 17.5 minutes until uniform, and obtain a functional mixed solution for use;

[0030] (2) Mix polyvinyl al...

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PUM

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Abstract

The invention discloses a medical adhesive for a clinical minor operation incision and a preparation method. The medical adhesive is prepared from, by weight, 3-5 parts of aloe protein, 3-5 parts of Chinese yam protein, 7-9 parts of soluble ginkgo polysaccharides, 12-15 parts of an aqueous polyoxyethylene solution, 3-5 parts of a-cyanoacrylate, 2-3 parts of chitosan, 12-14 parts of polyvinyl alcohol, 4-6 parts of multi-aldehyde sodium alginate, 1-3 parts of pectin, 1-3 parts of gelatin, 12-13 parts of hydrogenated camellia oil and the like. According to the medical adhesive for the clinical minor operation incision and the preparation method, by adopting the functional adding solution, the effects that the adhesive property is good, and disinfecting can be performed to inhibit wound infection are achieved; by adopting the processed chitosan, multi-aldehyde sodium alginate, pectin and gelatin as the main materials, the effects that the solidifying speed is low, and inflammation diminishing, healing and un-scaring of the clinical minor operation incision are facilitated are achieved; meanwhile, the hydrogenated camellia oil is adopted, and therefore a patient can achieve the good experience effect. The medical adhesive can meet the requirements of the clinical minor operation incision and is wide in raw material source and good in medical effect.

Description

Technical field [0001] The invention relates to the field of medical glue, in particular to a method for preparing medical glue for small outpatient surgical incisions. Background technique [0002] In surgical operations, minor outpatient operations are an important part. The degree of pain caused by the operation, the appearance of wounds after healing, and the size of the scars often affect the psychology and physiology of patients. Medical glue is used instead. Needles to reduce the undesirable consequences of needles in minor outpatient operations, has great medical value. [0003] At present, the main component of medical glue is a-cyanoacrylate, which has the fastest polymerization speed in biological tissues. Under the action of anions in the blood and tissue fluid of the wound, it can quickly polymerize and solidify into a film and be closely embedded with the wound. The wound can be firmly maintained in conjugation state, and the glue film can prevent blood cells and pla...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L26/00
CPCA61L26/0014A61L26/0019A61L26/0023A61L26/0028A61L26/0038A61L26/0057A61L26/0066A61L26/008A61L2300/252A61L2300/404C08L89/00C08L5/00C08L5/08C08L5/04C08L23/0853C08L29/04C08L71/02
Inventor 任新界
Owner 贵州通济智医科技有限公司
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