Medical adhesive for clinical minor operation incision and preparation method

A small surgery, incision technology, applied in the field of medical glue, can solve the problem of slow coagulation, achieve the effect of small coagulation speed, good glue properties, and promote anti-inflammatory healing without leaving scars

Active Publication Date: 2016-03-23
贵州通济智医科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, at present, medical glue is limited due to the limitation of raw materials and slow solidification during use.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] A medical glue for minor outpatient surgery incisions, including the following raw materials by weight (kg): aloe protein 3, yam protein 3, soluble ginkgo polysaccharide 7, casein 1, polyethylene oxide aqueous solution 12, hydrogenated camellia oil 12, a- Cyanoacrylate 4, polyvinyl alcohol 14, ethylene / vinyl acetate copolymer 13, chitosan 3, polyaldehyde sodium alginate 6, pectin 3, gelatin 3.

[0016] A preparation method of medical glue for outpatient minor surgery incision, comprising the following steps:

[0017] (1) Heat the polyethylene oxide aqueous solution to 53.5°C, then mix and stir the aloe protein, yam protein, soluble ginkgo polysaccharide, casein, and polyethylene oxide aqueous solution for 20-30 minutes to obtain a mixed solution for later use; heat the hydrogenated camellia oil to 185°C, then cooled to 105°C and added to the mixture, stirred for 17.5 minutes until uniform, and a functional mixture was obtained for later use;

[0018] (2) Mix polyvinyl ...

Embodiment 2

[0021] A medical glue for minor outpatient surgery incisions, including the following raw materials by weight (kg): aloe protein 4, yam protein 4, soluble ginkgo polysaccharide 4, casein 4, polyethylene oxide aqueous solution 13.5, hydrogenated camellia oil 12.5, a- Cyanoacrylate 4, polyvinyl alcohol 13, ethylene / vinyl acetate copolymer 11.5, chitosan 2.5, polyaldehyde sodium alginate 5, pectin 1.5, gelatin 1.5.

[0022] A preparation method of medical glue for outpatient minor surgery incision, comprising the following steps:

[0023] (1) Heat the polyethylene oxide aqueous solution to 53.5°C, then mix and stir the aloe protein, yam protein, soluble ginkgo polysaccharide, casein, and polyethylene oxide aqueous solution for 20-30 minutes to obtain a mixed solution for later use; heat the hydrogenated camellia oil to 185°C, then cooled to 105°C and added to the mixture, stirred for 17.5 minutes until uniform, and a functional mixture was obtained for later use;

[0024] (2) Mi...

Embodiment 3

[0027] A medical glue for minor outpatient surgery incisions, comprising the following raw materials by weight (kg): 5 aloe proteins, 5 yam proteins, 9 soluble ginkgo polysaccharides, 3 casein, 15 polyethylene oxide aqueous solutions, 13 hydrogenated camellia oil, a- Cyanoacrylate 4, polyvinyl alcohol 12, ethylene / vinyl acetate copolymer 10, chitosan 2, polyaldehyde sodium alginate 4, pectin 1, gelatin 1.

[0028] A preparation method of medical glue for outpatient minor surgery incision, comprising the following steps:

[0029] (1) Heat the polyethylene oxide aqueous solution to 53.5°C, then mix and stir the aloe protein, yam protein, soluble ginkgo polysaccharide, casein, and polyethylene oxide aqueous solution for 20-30 minutes to obtain a mixed solution for later use; heat the hydrogenated camellia oil to 185°C, then cooled to 105°C and added to the mixture, stirred for 17.5 minutes until uniform, and a functional mixture was obtained for later use;

[0030] (2) Mix polyv...

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PUM

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Abstract

The invention discloses a medical adhesive for a clinical minor operation incision and a preparation method. The medical adhesive is prepared from, by weight, 3-5 parts of aloe protein, 3-5 parts of Chinese yam protein, 7-9 parts of soluble ginkgo polysaccharides, 12-15 parts of an aqueous polyoxyethylene solution, 3-5 parts of a-cyanoacrylate, 2-3 parts of chitosan, 12-14 parts of polyvinyl alcohol, 4-6 parts of multi-aldehyde sodium alginate, 1-3 parts of pectin, 1-3 parts of gelatin, 12-13 parts of hydrogenated camellia oil and the like. According to the medical adhesive for the clinical minor operation incision and the preparation method, by adopting the functional adding solution, the effects that the adhesive property is good, and disinfecting can be performed to inhibit wound infection are achieved; by adopting the processed chitosan, multi-aldehyde sodium alginate, pectin and gelatin as the main materials, the effects that the solidifying speed is low, and inflammation diminishing, healing and un-scaring of the clinical minor operation incision are facilitated are achieved; meanwhile, the hydrogenated camellia oil is adopted, and therefore a patient can achieve the good experience effect. The medical adhesive can meet the requirements of the clinical minor operation incision and is wide in raw material source and good in medical effect.

Description

technical field [0001] The invention relates to the field of medical glue, in particular to a method for preparing medical glue for minor outpatient surgery incisions. Background technique [0002] In surgery, minor outpatient surgery is a very important part, and the degree of pain caused by the operation, the appearance of the wound after healing, and the size of the scar often have a certain impact on the patient's psychology and physiology. Medical glue is used instead Suturing needles to reduce the adverse consequences of outpatient minor surgery, has great medical value. [0003] At present, the main component of medical glue is a-cyanoacrylate, which has the fastest polymerization speed in biological tissues. Under the action of anions in wound blood and tissue fluid, it can quickly polymerize and solidify to form a film, which is tightly embedded with the wound. It can firmly maintain the apposition state of the wound, and the adhesive film can prevent blood cells a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00
CPCA61L26/0014A61L26/0019A61L26/0023A61L26/0028A61L26/0038A61L26/0057A61L26/0066A61L26/008A61L2300/252A61L2300/404C08L89/00C08L5/00C08L5/08C08L5/04C08L23/0853C08L29/04C08L71/02
Inventor 任新界
Owner 贵州通济智医科技有限公司
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