Preparation method of liermian capsule

A technology of Liermian and capsules, which is applied in the field of preparation of Liermian Capsules, can solve the problems of low extraction efficiency of active ingredients of drugs, inaccurate dosage control, and insufficient stability of quality, so as to improve the effective utilization rate and drug utilization. The effect of high efficiency and low production cost

Inactive Publication Date: 2016-04-06
CHENGDU JIUZHITANG JINDING PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Liermian capsules have the disadvantages of inaccurate dose control, unstable quality, and high production costs
The extrac

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0028] Embodiment 1: a kind of preparation method of Liermian medicament, described Liermian capsule is made up of Rhizoma Coptidis, cinnamon and starch, and the preparation method of described Liermian capsule comprises the following steps:

[0029] S1. Raw material preparation: Weigh each raw material according to the following formula proportions by weight, and set aside, the formula is: 630, cinnamon 105, starch 3.18;

[0030] S2. Pulverization: pulverize the cinnamon with a pulverizer, pass through a 100-mesh sieve, and make fine powder;

[0031] S3. Extract Coptis Rhizoma, which includes the following substeps:

[0032] S31. Boiling: Put the Coptis Rhizoma into the extraction tank, add water and boil it twice, the method of the first boiling is: add drinking water 9 times the weight of Coptis Rhizoma in the extraction tank, soak in cold for 30 minutes, heat until boiling Boil for 3 hours on high heat, filter to obtain filter residue and filtrate, and the filtrate is the...

Example Embodiment

[0040] Embodiment 2: a kind of preparation method of Liermian medicament, described Liermian capsule is made up of Rhizoma Coptidis, cinnamon and starch, and the preparation method of described Liermian capsule comprises the following steps:

[0041] S1. Raw material preparation: Weigh each raw material according to the following formula proportions by weight, and set aside, the formula is: 600, cinnamon 100, starch 2.5;

[0042] S2. Pulverization: pulverize the cinnamon with a pulverizer, pass through a 100-mesh sieve, and make fine powder;

[0043] S3. Extract Coptis Rhizoma, which includes the following substeps:

[0044] S31. Boiling: Put the Coptis Rhizoma into the extraction tank, add water and boil twice, the method of the first boiling is: add drinking water 10 times the weight of Coptis Rhizoma in the extraction tank, soak in cold for 60 minutes, heat until boiling Boil for 3.5 hours on high heat, filter to obtain filter residue and filtrate, and the filtrate is the ...

Example Embodiment

[0052] Embodiment 3: a kind of preparation method of Liermian medicament, described Liermian capsule is made up of Rhizoma Coptidis, cinnamon and starch, and the preparation method of described Liermian capsule comprises the following steps:

[0053] S1. Raw material preparation: Weigh each raw material according to the following formula proportions by weight, and set aside, the formula is: 660, cinnamon 110, starch 4;

[0054] S2. Pulverization: pulverize the cinnamon with a pulverizer, pass through a 100-mesh sieve, and make fine powder;

[0055] S3. Extract Coptis Rhizoma, which includes the following substeps:

[0056] S31. Boiling: Put the Coptis Rhizoma into the extraction tank, add water and boil twice, the method of the first boiling is: add drinking water 9.5 times the weight of Coptidis Rhizoma in the extraction tank, soak in cold for 45 minutes, heat until boiling Boil on high heat for 2.5 hours, filter to obtain filter residue and filtrate, and the filtrate is the...

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Abstract

The invention discloses a liermian capsule and a preparation method thereof. The liermian capsule is prepared from coptis chinensis, cinnamon and starch; and the preparation method of the liermian capsule comprises the following steps: preparing raw materials; crushing the raw materials; extracting the coptis chinensis; mixing cream powder; preparing dry cream powder; and carrying out spraying granulation and post-treatment. The extraction technology on the coptis chinensis and the cinnamon is further improved, so that the effective components in the raw medicinal materials are relatively well dissolved out, the effective utilization rate of the medicines is improved, and relatively great efficacy can be put into a play; meanwhile, the technological parameters are optimized, so that the dose of the liermian capsule is relatively accurate, the medicine utilization rate is high, and the production cost is relatively low. The liermian disclosed by the invention is a capsule, has the advantages of being convenient to carry, small in irritation to gastric mucosa, and relatively accurate in medicine release, and is also convenient to take by a patient; and the preparation method of the liermian capsule has the advantages of being simple to operate, convenient to prepare, low in cost and applicable to industrial large-scale production.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a preparation method of Liermian capsules. Background technique [0002] Coptis chinensis, (scientific name: Coptischinensis Franch.) aliases: Weilian, Chuanlian, chicken feet, belongs to Ranunculaceae, and Coptis chinensis is a perennial herb. Mainly produced in Hubei, Sichuan and other places. Coptis chinensis is a well-known traditional Chinese medicine, listed as top grade in "Shen Nong's Materia Medica". Contains a variety of alkaloids, mainly berberine, followed by methyl berberine, jatoline and so on. It has the effects of clearing away heat and dampness, purging fire and detoxifying, and is used to treat damp-heat and fullness, vomiting and acid regurgitation, diarrhea, jaundice, high fever and coma, hyperactivity of heart fire, upset and insomnia, vomiting of blood heat at the nose, red eyes, toothache, Diabetes, carbuncle and furuncle; external treatment of eczema, ...

Claims

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Application Information

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IPC IPC(8): A61K36/718A61K9/48A61P25/20
CPCA61K9/1652A61K36/54A61K36/718A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 张宁曾嵘陈曦蒋丽吕春艳
Owner CHENGDU JIUZHITANG JINDING PHARMA
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