Rh blood group antigen detection card

An antigen detection and detection card technology, which is applied in the field of biomedicine, can solve the problems that medical personnel are difficult to screen and determine the optimal components, affect blood quality and physical and chemical properties, and inconvenient for clinical use. Superior performance, improved typing sensitivity and accuracy

Inactive Publication Date: 2016-06-22
上海润普生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This technology improves upon previous methods by providing better stability during storage without causing excessive loss of its ability to absorb electrolytes from solution when stored under pressure. It achieves this through use of certain buffers made up mainly of different chemicals such as KPO3 (potash) Na2C03), TAESL(trifluoroacetic acid). Trisodsodiumsalt (TDS)). These buffers help improve the overall properties of the liquid phase but they may have negative side reactions if combined together due to their interaction between them. To address these issues, another type called gamma lactone was developed. GLAXOL® LS-200 is commonly available commercially today.

Problems solved by technology

This patented problem addressed in this patent relates to accurately identifying both types of blood called rhombi-type and non-rhombis-type based upon their respective characteristics such as molecular weight, solubility, reactivity towards various substances like proteins, nuclein, enzymes, etc., and how these factors contribute to determining whether there needs to receive therapy before receiving them during pregnancy without causing harmful side effects.

Method used

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  • Rh blood group antigen detection card
  • Rh blood group antigen detection card
  • Rh blood group antigen detection card

Examples

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Embodiment 1

[0049] Rh blood type detection card, including at least one detection group on the detection card, each detection group has 4 micro-column gel tubes, which are respectively the gel tube containing the monoclonal anti-C antibody of IgM nature and the anti-C antibody of IgM nature. Gel tubes containing monoclonal anti-C antibodies of IgM nature, gel tubes containing monoclonal anti-E antibodies of IgM nature, gel tubes containing monoclonal anti-E antibodies of IgM nature,

[0050] The preparation method of the test card comprises the following steps:

[0051] a. Preparation of gel suspension medium

[0052] The composition of the gel suspension medium is as follows:

[0053] Methylparaben 6.0×10 -4 g / ml

[0054] Propylparaben 2.0 x 10 -4 g / ml

[0055] Glycine 1.75×10 -2 g / ml

[0056] Sodium chloride 1.8×10 -3 g / ml

[0057] Potassium dihydrogen phosphate 1.2×10 -4 g / ml

[0058] Disodium hydrogen phosphate 2×10 -4 g / ml

[0059] Trisodium citrate 8×10 -4 g / ml

[0060]...

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Abstract

The invention belongs to the field of biological medicine, and particularly relates to an Rh blood typing card and a preparation method thereof. The detection card comprises at least one detection group, wherein each detection group comprises four micro-column gel tubes, the four micro-column gel tubes include a gel tube containing a monoclonal anti-C antibody with IgM nature, a gel tube containing a monoclonal anti-c antibody with IgM nature, a gel tube containing a monoclonal anti-E antibody with IgM nature and a gel tube containing a monoclonal anti-e antibody with IgM nature; a gel suspending medium is prepared from monopotassium phosphate, disodium hydrogen phosphate, trisodium citrate and bovine serum albumin. Meanwhile, trisodium citrate has an anticoagulation effect, separation and classification treatment of typing tools and content are facilitated, the treatment cost of medical waste is reduced, and the treatment difficulty is reduced.

Description

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Claims

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Application Information

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Owner 上海润普生物技术有限公司
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