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Hydrogel for slow release of tripterygium hypoglaucum hutch extract and paper diaper for the aged made of same

A technology of extract and torch flower, which is applied in the field of traditional Chinese medicine health care, can solve the problems of toxic and side effects, achieve the effect of long duration, simple and easy preparation method, and avoid cumbersome problems

Inactive Publication Date: 2016-07-06
CHONGQING ACAD OF CHINESE MATERIA MEDICA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But Kunming Begonia medicine also has certain toxic and side effects. According to reports, after Kunming Begonia Tablets (produced by Kunming Pharmaceutical Company Pharmaceutical Factory), gastrointestinal side effects such as chest tightness and discomfort, nausea and vomiting

Method used

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  • Hydrogel for slow release of tripterygium hypoglaucum hutch extract and paper diaper for the aged made of same
  • Hydrogel for slow release of tripterygium hypoglaucum hutch extract and paper diaper for the aged made of same
  • Hydrogel for slow release of tripterygium hypoglaucum hutch extract and paper diaper for the aged made of same

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] The preparation of embodiment 1 Huobahua extract

[0033] Slice the Huoba flower root medicinal material, add water and decoct 2-5 times, combine the filtrate, heat and concentrate to a clear paste with a density of 1.05-1.07, add ethanol to the clear paste, adjust the ethanol concentration to 50-80%, let stand, and precipitate Filtrate, recover under reduced pressure at a temperature of 40-60°C, recover ethanol until it has no alcohol smell, the density of the thick paste is 1.30-1.35, and obtain the Huobahua root extract.

[0034] Take any one or more of the torch flower stems, branches, roots, root bark and peeled root core, slice them, and obtain the corresponding torch flower extract according to the above method.

Embodiment 2

[0035] The preparation of the hydrogel of embodiment 2 sustained-release torch flower extract

[0036] Dissolve chitosan in vinyl acetate solution at 25-35°C, stir to dissolve, add 1.5% glutaraldehyde in vinyl acetate solution, and react with magnetic stirring for 36 hours at 50°C to obtain transparent chitosan hydrogel ball; the molar ratio of chitosan to vinyl acetate is 1:15. Then in 10 grams of transparent chitosan hydrogel microspheres, add 1 gram of torch flower extract thick paste with a relative density of 1.30-1.35, shake on a shaker, add 5 grams of sodium chloride and 8 grams of absolute ethanol, and obtain slow A hydrogel releasing torch flower extract.

[0037] The hydrogel of the sustained-release torch flower extract obtained by the method uses vinyl acetate as a monomer to obtain a nanocomposite gel through in-situ free radical polymerization. The method has a simple process, not only effectively removes the clay residue in the polymer, but also greatly improv...

Embodiment 3

[0038] The preparation of the hydrogel of embodiment 3 sustained-release torch flower extract

[0039]Dissolve chitosan in vinyl acetate solution at 25-35°C, stir to dissolve, add 3.5% glutaraldehyde in vinyl acetate solution, and react with magnetic stirring for 50 hours at 70°C to obtain transparent chitosan hydrogel ball; the molar ratio of chitosan to vinyl acetate is 1:30. Then in 15 grams of transparent chitosan hydrogel microspheres, add 1 gram of the thick paste of the torch flower extract with a relative density of 1.30-1.35, shake on a shaker, add 10 grams of sodium chloride and 5 grams of absolute ethanol, and obtain slow A hydrogel releasing torch flower extract.

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Abstract

The invention belongs to the field of traditional Chinese medical care, and particularly relates to hydrogel for slow release of tripterygium hypoglaucum hutch extract and a paper diaper for the aged made of the same.Esterified chitosan serves as the water-soluble nano-porous frame carrier of the hydrogel, and the tripterygium hypoglaucum hutch extract serves as the solubilization slow release object.The paper diaper for the aged comprises a healthcare protection layer, an adsorption core coating layer, an adsorption core layer and a nano-hydrogel layer from outside to inside in sequence, wherein the nano-hydrogel layer is mainly formed by the hydrogel for slow release of the tripterygium hypoglaucum hutch extract.The hydrogel for slow release of the tripterygium hypoglaucum hutch extract can effectively reduce the peak plasma concentration of drugs and is a slow release preparation with a remarkable treatment effect.By the adoption of the paper diaper for the aged, the trouble of frequent clinical medication everyday and problems caused thereby are avoided, and medication efficiency and safety and patient compliance are improved.The paper diaper for the aged is mainly used for adjuvant treatment of rheumatoid arthritis, lupus erythematosus, chronic nephritis and autoimmune hemolytic anemia.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine health care, in particular to a hydrogel of slow-release torch flower extract and elderly paper diapers prepared therefrom. Background technique [0002] The structure of traditional diapers is basically composed of a soft cotton layer on the surface, an absorbent core layer, a waterproof layer and a bottom fabric layer, all of which are used to prevent urine from staining clothes. As China gradually enters an aging society, in order to be considerate of the elderly, diaper products are what the elderly need. The elderly are bedridden for a long time due to illness, and they are prone to skin infections, bacterial infections, and bedsores, which bring considerable pain to the patients. At present, the function of diapers is mainly to absorb moisture, and cannot sterilize, let alone damage the patient’s wounds. Treat the affected area. [0003] The scientific name of torch flower is Ku...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/37A61K9/06A61K47/36A61P19/02A61P29/00A61P37/02A61P13/12A61P7/06A61F13/496
CPCA61F13/496A61K9/0002A61K9/06A61K36/37A61K47/36
Inventor 谭红军吴振
Owner CHONGQING ACAD OF CHINESE MATERIA MEDICA
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