Preparation for treating chronic diabetic foot ulcers and preparation method and application thereof

A technology for chronic ulcers and diabetic feet, applied in the field of medicine, can solve problems such as easy to cause other complications, large side effects, and inability to cure symptoms, and achieve good wound healing effects, improved resistance, and no toxic side effects

Inactive Publication Date: 2016-07-06
迟海燕
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above-mentioned drugs can only assist in the treatment of diabetic foot, but cannot cure the symptoms, and have large side effects, which can easily lead to other complications

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] In an embodiment of the present invention, a preparation for treating chronic diabetic foot ulcers is composed of the following raw materials in parts by weight: 10 parts of dog ant grass, 22 parts of leech seven, 15 parts of four-leaf clover, and 2 parts of star anise lotus.

[0024] Pulverize dog ant grass and leech seven through a 100-mesh sieve, add an ethanol solution with a volume concentration of 75% that is 80 times the mass of the two, and treat it under high temperature and pressure at 4MPa and 100°C for 1 hour, and take the filtrate after filtration to prepare a mixed solution a. Crush the four-leaf clover, pass through a 200-mesh sieve, add deionized water 13 times its mass, heat at 110°C for 1.5h, and filter to obtain the filtrate to prepare mixture B. The star anise lotus is crushed through a 60-mesh sieve, then vinegar of 0.5 times its mass is added, fried at 75°C for 15 minutes, and then ground through a 200-mesh sieve to obtain star anise lotus powder. ...

Embodiment 2

[0026] In an embodiment of the present invention, a preparation for treating chronic diabetic foot ulcers is composed of the following raw materials in parts by weight: 18 parts of dog ant grass, 30 parts of leech seven, 23 parts of four-leaf clover, and 8 parts of star anise lotus.

[0027] Pulverize dog ant grass and leeches seven through a 150-mesh sieve, add 75% ethanol solution 10 times the mass of the two, treat at 5MPa, 100-120°C high temperature and high pressure for 1-1.3h, filter and take the filtrate to prepare a mixed Liquid A. Crush the four-leaf clover, pass through a 200-mesh sieve, add 15 times the mass of deionized water, heat at 115°C for 2 hours, and filter the filtrate to prepare mixture B. The star anise lotus is crushed through a 60-mesh sieve, then vinegar of 0.8 times its mass is added, fried at 80°C for 20 minutes, and then ground through a 200-mesh sieve to obtain star anise lotus powder. Mix mixture A and mixture B, heat and stir at 150°C for 20 min...

Embodiment 3

[0029] In an embodiment of the present invention, a preparation for treating chronic diabetic foot ulcers is composed of the following raw materials in parts by weight: 12 parts of dog ant grass, 24 parts of leech seven, 17 parts of four-leaf clover, and 4 parts of star anise.

[0030] Crush dog ants and leech seven through a 150-mesh sieve, add 9 times the mass of the two 75% ethanol solution, treat at 4.5 MPa, 110 ° C under high temperature and high pressure for 1.3 h, filter and take the filtrate to prepare mixed liquid A. Crush the four-leaf clover, pass through a 200-mesh sieve, add deionized water 14 times its mass, heat at 114°C for 2 hours, and filter the filtrate to prepare mixture B. The star anise lotus is crushed through a 60-mesh sieve, then vinegar with a mass of 0.7 times is added, then fried at 78°C for 20 minutes, and then ground through a 200-mesh sieve to obtain star anise lotus powder. Mix mixture A and mixture B, heat and stir at 145°C for 20 minutes, then...

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PUM

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Abstract

The invention discloses a preparation for treating diabetic foot chronic ulcer and its preparation method and application. The preparation is composed of the following raw materials in parts by weight: 10-18 parts of dog ant grass, 22-30 parts of leech seven, and four-leaf clover 15‑23 parts, star anise 2‑8 parts. Crush and sieve dog ant grass and leech seven, add 75% ethanol solution, process under high temperature and high pressure, filter and take the filtrate to obtain mixed solution A; crush and sieve the four-leaf clover, add deionized water to heat, filter and take Mixture B is obtained from the filtrate; the star anise lotus is crushed and sieved, then fried with vinegar, ground and sieved to obtain star anise lotus powder; the mixture A and mixture B are mixed, heated and stirred, and the star anise lotus powder is added, heated and stirred, and cooled to room temperature. have to. The present invention clears away heat and detoxifies, removes putrefaction and promotes granulation, promotes blood circulation and removes blood stasis, warms meridian and collaterals, promotes qi and analgesia, kills bacteria and reduces inflammation through the joint action of various raw materials, and is used for treating diabetic foot chronic ulcers, with obvious therapeutic effect, good wound healing effect, and no toxic side effects , no recurrence after curing.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a preparation for treating diabetic foot chronic ulcer, a preparation method and application thereof. Background technique [0002] The foot is a complex target organ in diabetes, a multisystem disease. Diabetic patients due to peripheral neuropathy and peripheral vascular disease combine excessive mechanical pressure, which can cause damage and deformity of the soft tissue and bone joint system of the foot, and then cause a series of foot problems, from mild neurological symptoms to severe ulcers , infection, vascular disease, Charcot arthropathy, and neuropathic fractures. If aggressive treatment does not adequately address the symptoms and complications that develop in the lower extremities, the consequences can be disastrous. [0003] At present, the medicines used to treat diabetic foot mainly include: 1. Improve microcirculation treatment, mainly include anisodamine, pro...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/74A61P3/10A61P17/02
CPCA61K36/48A61K9/0014A61K36/185A61K36/29A61K36/74A61K2236/331A61K2236/333
Inventor 迟海燕周玉萍
Owner 迟海燕
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