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Moisturizing gel containing hydrolyzed pearl powder flexible nano liposome

A technology of hydrolyzed pearl powder and nanoliposome, applied in the field of skin care products and liposome skin care products, can solve problems such as decreased elasticity, dullness, seborrheic aging, etc., to improve softness, enhance metabolism, and repair skin barrier effect

Inactive Publication Date: 2016-07-27
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In order to overcome the existing shortcomings of the prior art, the purpose of the present invention is to provide a moisturizing gel containing hydrolyzed pearl powder flexible nano-liposomes, which uses liposomes as carriers to carry nutrients to the deep layer of the skin and be absorbed by the human body. Fully absorbed and utilized, this skin care product can solve the problems of dull skin, decreased elasticity, seborrheic aging, and has a good moisturizing and oil control effect

Method used

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  • Moisturizing gel containing hydrolyzed pearl powder flexible nano liposome
  • Moisturizing gel containing hydrolyzed pearl powder flexible nano liposome
  • Moisturizing gel containing hydrolyzed pearl powder flexible nano liposome

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] 1. The composition of hydrolyzed pearl powder flexible nano liposome:

[0026] Soy Lecithin 5.5wt%

[0027] Sodium cholate 1.5wt%

[0028] Hydrolyzed Pearl Powder 1.5wt%

[0029] 2. Preparation of hydrolyzed pearl powder flexible nano-liposomes:

[0030] (1) Quantitatively weigh soybean lecithin, sodium cholate, and hydrolyzed pearl powder and dissolve them in chloroform;

[0031] (2) Water bath at 37.5°C, remove chloroform under reduced pressure;

[0032] (3) vacuumize and store for 5h;

[0033] (4) Add isotonic phosphate buffer (pH7.4), hydrate and then rotate on a rotary evaporator for 1 hour to remove the organic solvent to form a flexible liposome suspension;

[0034] (5) The liposome suspension was placed in an ice-water bath, subjected to probe-type intermittent ultrasound for 30 minutes, and then filtered with a 0.2 μm filter head to obtain flexible nanoliposomes.

[0035] 3. See Table 1 for the composition of the moisturizing gel.

[0036] Table 1

[00...

Embodiment 2

[0044] Example 2: Effect Detection

[0045] The moisturizing gel was used by 80 women of various skin types ranging in age from 20 to 60, each of whom had previously used at least one natural or organic skin care product daily from a reputable or cosmeceutical brand. Fifty of the participants had sensitive skin, defined as current symptoms such as flushing, tightness, scaling, or acneiform lesions. The participants used the moisturizing gel of the present invention on the cleansed face every morning and evening, replacing the previous skin care products. After four weeks of use, participants completed questionnaires. The research results are shown in Table 2.

[0046] Table 2

[0047]

[0048]

[0049] Participants agree that the product is non-irritating to the skin. After use, the skin is obviously comfortable, soft, and non-greasy. It has obvious sunscreen and whitening effects, has a good repairing effect on sunburn, and reduces acne scars.

Embodiment 3

[0050] Embodiment 3: moisturizing performance test

[0051] The test is divided into an invention group and a control group, and the invention group uses the skin care product prepared in Example 1.

[0052] The moisturizer of the control group does not contain the hyaluronic acid in the vegetable combination oil of Example 1, and the other components, content and preparation method are exactly the same as those of Example 1.

[0053] Two groups were randomly selected, and 10 female volunteers aged between 18 and 50 in each group were tested. During the test, the forehead is used as the test site, and a fixed area with a size of 2 square centimeters is drawn on the forehead of the face as the test area. In an indoor environment at 20°C and a relative humidity of 50%, use the Corneometer CM820 skin moisture meter to test the moisture content of the forehead skin of two groups of volunteers, and the results are expressed by the set humidity measurement value (MoistureMeasuremen...

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Abstract

The invention discloses moisturizing gel containing hydrolyzed pearl powder flexible nano liposome. The moisturizing gel is prepared by heating, mixing and homogenizing the hydrolyzed pearl powder flexible nano liposome, sodium hyaluronate, beta-glucan, acryloyl dimethyl ammonium taurine copolymer, hydroxyethyl urea, panthenol, nicotinamide, skin moistening esters, N,N'-1,2-ethanediylbis-1-aspartic acid and deionized water. The moisturizing gel is simple in process, multiple nutrition substances including amino acid, microelements, polypeptide and the like contained in the hydrolyzed pearl powder are utilized, metabolism of skin epithelial cells and dermal fibroblasts is effectively enhanced, and the skin repair function is promoted. The moisturizing gel is natural, mild, nearly free of stimulation and capable of penetrating through the skin surface of the human body easily, is infused with cells to achieve effects, can be used for moistening skin, preserving moisture and repairing skin barriers for a long time, has good water supplementation, moisture preservation and repairing effects for oily and mixed skin, sensitive skin and the like, and the skin can also be effectively whitened.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and relates to a skin care product, in particular to a moisturizing gel containing hydrolyzed pearl powder flexible nano-liposomes, which can solve the problems of dull skin, decreased elasticity, and seborrheic aging , Liposome skin care product with good moisturizing and oil control effect. Background technique [0002] Skin consists of epidermis, dermis, subcutaneous fat and appendages. The epidermis is the outermost layer of the skin and is divided from inside to outside: basal cell layer, acanthocyte layer, granule cell layer, clear cell layer and keratinocyte layer. Skin appendages include hair, hair follicles, sebaceous glands, and sweat glands. The skin absorbs external substances mainly through three ways, namely the stratum corneum, pilosebaceous glands and sweat duct orifices. Among them, the stratum corneum is the most important way for the skin to absorb. Under normal circumstan...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/98A61K8/14A61K8/81A61K8/73A61K8/67A61K8/44A61K8/42A61Q19/00
CPCA61K8/987A61K8/14A61K8/42A61K8/44A61K8/673A61K8/73A61K8/817A61Q19/00
Inventor 韩睿程浩
Owner ZHEJIANG UNIV
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