Medicine for reducing blood glucose and relieving diabetes gastrointestinal dysfunction and preparation method

A technology for gastrointestinal dysfunction and diabetes, which is applied in the fields of drugs, health food and pharmaceutical compositions for lowering blood sugar and improving gastrointestinal dysfunction in diabetes, and can solve problems such as the inability to block or reverse the process, and achieve rapid relief of clinical symptoms, The effect is stable and long-lasting, and the production process is easy to operate

Inactive Publication Date: 2016-08-03
JILIN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Existing treatments can only delay the development of diabetes to a certain extent, but cannot stop or reverse its progress

Method used

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  • Medicine for reducing blood glucose and relieving diabetes gastrointestinal dysfunction and preparation method
  • Medicine for reducing blood glucose and relieving diabetes gastrointestinal dysfunction and preparation method
  • Medicine for reducing blood glucose and relieving diabetes gastrointestinal dysfunction and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0082] 1. Preparation of ginseng extract: Take 1 kg of ginseng and crush it, add 6 times the amount of water, soak overnight, boil for 3 hours, let it cool, and filter; add 5 times the amount of water to the residue, boil for 2 hours, filter; add 4 times the amount of water to the residue , boiled for 2 hours; filtered, combined filtrates, concentrated, dried under reduced pressure at 80°C to obtain the extract;

[0083] 2. Preparation of fenugreek extract powder: take 1.5kg of fenugreek and wash it, dry it, add 6 times of 50% ethanol solution, reflux extraction 3 times, each time for 4 hours, filter; combine the filtrate and concentrate into For the extract, add 0.08 times of soluble starch, mix well, heat, dry at 80°C, cool, pulverize, pass through an 80-mesh sieve to obtain fenugreek extract powder;

[0084] 3. Pass the product prepared in step 1) and step 2) through an 80-mesh sieve, and mix it at a ratio of 1:1.5 to obtain the product.

Embodiment 2

[0086] 1. Preparation of ginseng extract: Take 2kg of ginseng and crush it, add 6 times the amount of water, soak overnight, boil for 3 hours, let it cool, and filter; add 5 times the amount of water to the residue, boil for 2 hours, filter; add 4 times the amount of water to the residue , boiled for 2 hours; filtered, combined filtrates, concentrated, dried under reduced pressure at 80°C to obtain the extract;

[0087] 2. Preparation of fenugreek extract powder: take 2 kg of fenugreek and wash it, dry it, add 6 times of 50% ethanol solution, reflux extraction 3 times, each time for 4 hours, and filter; combine the filtrates and concentrate to obtain paste, add 0.08 times of soluble starch, mix well, heat, dry at 80°C, cool, pulverize, pass through 80-mesh sieve to obtain fenugreek extract powder;

[0088] 3. Pass the product prepared in step 1) and step 2) through an 80-mesh sieve, and mix it at a ratio of 1:1 to obtain the product.

Embodiment 3

[0090] 1. Preparation of ginseng extract: Take 1 kg of ginseng and crush it, add 6 times the amount of water, soak overnight, boil for 3 hours, let it cool, and filter; add 5 times the amount of water to the residue, boil for 2 hours, filter; add 4 times the amount of water to the residue , boiled for 2 hours; filtered, combined filtrates, concentrated, dried under reduced pressure at 80°C to obtain the extract;

[0091] 2. Preparation of fenugreek extract powder: take 2 kg of fenugreek and wash it, dry it, add 6 times of 50% ethanol solution, reflux extraction 3 times, each time for 4 hours, and filter; combine the filtrates and concentrate to obtain paste, add 0.08 times of soluble starch, mix well, heat, dry at 80°C, cool, pulverize, pass through 80-mesh sieve to obtain fenugreek extract powder;

[0092] 3. Pass the product prepared in step 1) and step 2) through an 80-mesh sieve, and mix it at a ratio of 1:2 to obtain the product.

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Abstract

The invention provides a pharmaceutical composition and healthcare food capable of reducing blood glucose and relieving diabetes gastrointestinal dysfunction and provides a preparation method of the pharmaceutical composition.The experiment on the aspect of pharmacology shows that the pharmaceutical composition prepared through reasonable compatibility (the ratio is 1:2) of ginseng extract and fenugreek extract powder has the effect of reducing blood glucose and is obviously superior to the ginseng extract and the fenugreek extract powder which are independently applied at the equivalent dose.The pharmaceutical composition can relieve the gastrointestinal dysfunction symptom caused by diabetes, and the function is not found when the ginseng extract and the fenugreek extract powder are independently applied at the equivalent dose.

Description

[0001] technical field [0002] The invention relates to a pharmaceutical composition, in particular to a medicine and health food for lowering blood sugar and improving gastrointestinal dysfunction in diabetes, and also provides a preparation method thereof, which belongs to the field of traditional Chinese medicine. Background technique [0003] Diabetes mellitus is a group of systemic chronic metabolic diseases characterized by chronic elevated blood glucose (referred to as blood sugar) levels. Hyperglycemia is caused by defects in insulin secretion and / or insulin action. In addition to carbohydrates, there are abnormalities in protein and fat metabolism. Prolonged illness can cause multisystem complications. At present, the treatment of diabetes is mainly combined with diet control and hypoglycemic drugs (for type 2 diabetes) or insulin supplementation to control blood sugar and prevent complications. Long-term use has side effects such as hypoglycemia and gastrointesti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/48A61P3/10A61P1/04A61P1/14A61P1/00A61P1/08A61P1/10A61P1/12
CPCA61K36/258A61K36/48A61K47/36A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 石艳陈燕萍睢建春王志才陈祯王俊贤
Owner JILIN UNIV
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