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Alginate dressing containing wound-healing promoting medicine and preparing method thereof

A technology of alginate and wound healing, applied in medical science, bandages, absorbent pads, etc., can solve problems such as easy adhesion of new tissues, secondary trauma of wounds, and destruction of growth factors, so as to promote wound healing, promote healing, reduce effect on pain

Inactive Publication Date: 2016-08-17
SICHUAN KUIXING MEDICAL POLYMER PROD CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional dressings used on wounds mainly play an isolation and antibacterial role, but often lead to dryness of the wound, damage to healthy growth factors, and easy adhesion to new tissue, which will lead to secondary trauma of the wound when the dressing is removed

Method used

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  • Alginate dressing containing wound-healing promoting medicine and preparing method thereof
  • Alginate dressing containing wound-healing promoting medicine and preparing method thereof
  • Alginate dressing containing wound-healing promoting medicine and preparing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0067] prescription:

[0068]

[0069]

[0070] The preparation method is:

[0071] (1) Prepare the dressing with the prescribed amount of calcium alginate fiber through the non-woven acupuncture process, and the weight per unit area of ​​the dressing is about 150g / m 2 (2) phenytoin sodium, lidocaine hydrochloride, Tween 20, sodium hydroxide and sodium chloride are dissolved in an appropriate amount of purified water, and the gained solution is evenly sprayed on the surface of the above-mentioned dressing with nanometer or micron droplet mode (3) drying the obtained dressing in ventilation and drying equipment; (4) cutting the dried dressing into an appropriate size and packaging and sterilizing it to obtain the alginate dressing.

[0072] The prepared alginate dressing can absorb the exudate, provide a moist wound healing environment, promote the growth of granulation tissue, and accelerate wound healing.

[0073]Cover the affected area with alginate dressing, which c...

Embodiment 2

[0075] prescription:

[0076]

[0077] The preparation method is:

[0078] (1) Prepare the dressing with the prescribed amount of calcium alginate fiber through the non-woven acupuncture process, and the weight per unit area of ​​the dressing is about 200g / m 2 ;

[0079] (2) Disperse the phenytoin, hydrochloric acid, borax and polyethylene glycol 4000 of the prescribed amount in an appropriate amount of 50% ethanol solution to prepare a suspension, and spray the suspension on the surface of the above-mentioned dressing in the form of a spray;

[0080] (3) Gained dressing is placed in ventilation and drying equipment to dry;

[0081] (4) Cut the dried dressing into a suitable size and package and sterilize it to obtain the alginate dressing.

[0082] The prepared alginate dressing can absorb exudate, provide a moist wound healing environment, promote the growth of granulation tissue, and accelerate wound healing.

[0083] Cover the affected area with a dressing, which ca...

Embodiment 3

[0085] prescription:

[0086] Calcium alginate 93 parts

[0087] phenytoin 5 parts

[0088] Tween 80 2 servings

[0089] The preparation method is:

[0090] (1) phenytoin sodium and Tween 80 of the prescription quantity are dissolved in an appropriate amount of 25% ethanol solution;

[0091] (2) Soak calcium alginate fibers of suitable length and fineness in the obtained solution for 30 to 60 minutes, and then dry them;

[0092] (3) The dressing is prepared by the non-woven acupuncture process, and the weight per unit area of ​​the dressing is about 170g / m 2 ;

[0093] (4) Cut the dressing into a suitable size and package and sterilize it to obtain the alginate dressing.

[0094] The prepared alginate dressing can absorb exudate, provide a moist wound healing environment, promote the growth of granulation tissue, and accelerate wound healing.

[0095] Cover the affected area with a dressing, which can be supplemented with secondary dressings such as bandages.

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Abstract

The invention discloses an alginate dressing containing wound-healing promoting medicine and a preparing method thereof. The alginate dressing comprises, by weight, 50-99.9 parts of alginate, 0.1-25 parts of wound-healing promoting medicine and 0.01-15 parts of surfactant. Compared with the prior art, the alginate dressing containing the wound-healing promoting medicine can be used for a difficult-healing wound surface and a tissue-deletion wound surface, exudation liquid is absorbed, the wet environment required by wound surface healing is provided, and granulation growth of the wound surface is promoted. The dressing is high in exudation-liquid absorbing capacity, a wound is free of adhesion, wound exudation liquid is absorbed, then gel can be rapidly formed, the high moisturizing performance is achieved, wound healing can be further effectively promoted, and the repair time of the wound surface is shortened; the dressing for effectively promoting wound-surface healing is provided for burn wounding patients and the like.

Description

technical field [0001] The invention relates to the technical field of wound dressings, in particular to an alginate dressing containing wound healing promoting medicine and a preparation method thereof. Background technique [0002] The skin and mucous membranes of the human body are the barriers to maintain the stability of the human body environment and prevent the invasion of microorganisms. Damage to the skin and mucous membranes caused by ulcers, trauma, burns and inflammation will cause a series of problems in the body, such as bacterial infection, increased metabolism, Excessive water and protein loss, endocrine and immune system dysfunction, etc., may be life-threatening in severe cases. When the skin and mucous membrane are injured, a suitable dressing should be selected to cover the wound. It can maintain a moist environment for the wound, absorb secretions, relieve pain and control bleeding, thereby promoting rapid wound healing. [0003] The use of dressings is...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/44A61L15/28A61L15/60
CPCA61L15/44A61L15/28A61L15/60A61L2300/204A61L2300/402A61L2300/41A61L2300/412
Inventor 莫始奎
Owner SICHUAN KUIXING MEDICAL POLYMER PROD CO LTD
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