Systems and methods for electrical stimulation of biological systems

A technology of electrical stimulation and electrodes, applied in electrotherapy, physical therapy, therapy, etc., can solve problems such as unresolved anatomical factors

Inactive Publication Date: 2016-08-24
ENDOSTIM INC
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

[0019] While current electrical stimulation systems are effective in treating GER

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  • Systems and methods for electrical stimulation of biological systems
  • Systems and methods for electrical stimulation of biological systems
  • Systems and methods for electrical stimulation of biological systems

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Embodiment Construction

[0105] This specification discloses a programmable, implantable electromedical device for the treatment of gastroesophageal reflux disease (GERD). The present specification discloses systems and methods for treating gastroesophageal reflux disease (GERD) in a patient by electrically stimulating portions of the lower esophagus and / or stomach to cause an increase in the length of the high pressure zone of the lower esophageal sphincter (LES) . In one embodiment, the systems and methods of the present invention increase the length of the high pressure region of the LES without changing the manometric maximum pressure in the region of the LES. In other words, the stimulation provided by the system increases the length of the high pressure zone without changing the overall pressure.

[0106] In one embodiment, a system for increasing the length of the LES high voltage zone provides electrical stimulation in the LES. In another embodiment, the system provides electrical stimulatio...

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Abstract

Systems and methods for the treatment of gastroesophageal reflux disease (GERD) include at least one electrically stimulating electrode coupled to a pulse generator. Individuals with GERD are treated by implanting a stimulation device within and/or proximate the patient's lower esophageal sphincter, gastric fundus, or other nearby gastrointestinal structures and applying electrical stimulation to the patient's lower esophageal sphincter and/or fundus, in accordance with certain predefined protocols. Electrical stimulation provided by the disclosed systems results in an increase in the length of the high pressure zone of the LES and/or modulation of the receptive relaxation response of the fundus to decrease gastric pressure, creating a longer barrier to the reflux of gastric contents or increasing functional lower esophageal pressure respectively, thereby treating GERD.

Description

[0001] cross reference [0002] This application relies on U.S. Provisional Patent Application No. 61 / 906,812, entitled "Systems and Methods for Increasing the Length of the Lower Esophageal Sphincter High Pressure Zone," and filed November 20, 2013, and entitled "Systems and Methods for Modulating the Receptive Relaxation of the Fundus” and achieved priority in U.S. Provisional Patent Application No. 61 / 906,815, filed November 20, 2013. [0003] This application is also a continuation-in-part of U.S. Patent Application No. 14 / 500,856, entitled "Device and Implantation System for Electrical Stimulation of Biological Systems," filed September 29, 2014, which is of the same title and a continuation of U.S. Patent Application No. 14 / 201,766, filed March 7, 2014 (the "766" application), which is the U.S. patent application of the same title and filed on February 7, 2014. Continuation-in-Part of Patent Application Serial No. 14 / 175,927, which is U.S. Patent Application Serial No. 13...

Claims

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Application Information

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IPC IPC(8): A61N1/36
CPCA61N1/36007A61N1/3614
Inventor V.K.夏尔马S.波利克尔
Owner ENDOSTIM INC
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