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Method and apparatus for distributing a plasma sample

A technology of blood plasma and equipment, applied in biological testing, material inspection products, color/spectral characteristic measurement, etc., can solve problems such as obstacles, and achieve the effect of rapid and automatic inspection

Active Publication Date: 2019-08-23
F HOFFMANN LA ROCHE & CO AG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, according to the current point of view, such a label prevents that the transparency of the container can be fully exploited to carry out the pre-analysis of the plasma sample by means of optical methods.

Method used

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  • Method and apparatus for distributing a plasma sample
  • Method and apparatus for distributing a plasma sample

Examples

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Embodiment Construction

[0072] figure 1Typical schematically illustrated transmission spectra of good, icteric, hemolytic and lipemic samples are shown. The wavelength (λ) in the range of 450 nm to 700 nm, ie approximately in the visible spectrum, is shown here on the abscissa. Transmission (T) with values ​​from 0% to 100% is shown on the vertical axis.

[0073] The solid curve shows a typical transmission spectrum of a good sample. It can be seen here that the value of the transmission increases from approximately 0% to 100% over the shown wavelength range from 450 nm to 700 nm. The curve is structured between 550 nm and 600 nm, more precisely with maxima and minima.

[0074] The dashed curve shows a typical transmission spectrum of an icteric sample. It can be seen that in the range below about 600 nm the transmission is below that of the good sample. This can be used to identify icteric specimens. In particular, the value of the transmission at a wavelength of 470 nm is smaller than in the ...

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PUM

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Abstract

A device and method for assigning a blood plasma sample to a class from a predetermined set of classes are presented. The set of classes comprises a good class, a lipemic class, a hemolytic class and an icteric class. For assignment to one of the classes, the blood plasma sample is exposed to light and measurement values dependent on transmitted or scattered light power are evaluated in order to carry out an assignment.

Description

technical field [0001] The invention relates to a method and a device for assigning a plasma sample to classes from a predefined class set, the plasma sample being in an at least partially transparent container. Background technique [0002] Blood samples are often used to diagnose certain diseases or also to prove criminal or illegal acts, such as drug use or driving under the influence of alcohol. Such blood samples are typically filled into light-transparent containers in the form of plastic vials, wherein the vials are configured like test tubes. In this vial, the sample is typically centrifuged prior to further analysis steps, whereby a blood clot forms at the lower end of the vial in which all the cellular components of the blood sample are concentrated. Above the clot is typically plasma, which essentially contains the liquid components of the blood sample. The plasma forming the blood sample is usually analyzed in a subsequent analysis step. [0003] It often make...

Claims

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Application Information

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IPC IPC(8): G01N21/25G01N21/27G01N33/68
CPCG01N21/31G01N33/49
Inventor D.克利内克M.克勒
Owner F HOFFMANN LA ROCHE & CO AG