Anti-obesity strain of lactic acid bacteria and uses in food and pharmaceutical compositions

A technology of lactic acid bacteria and strains, applied in the field of lactic acid bacteria strains and their application in food composition and medical composition

Active Publication Date: 2016-10-05
安徽锦乔生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Generally, eating products containing lactic acid bacteria (LAB) only has the effect of adjusting the health of the intestinal tract. Although tens of thousand...

Method used

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  • Anti-obesity strain of lactic acid bacteria and uses in food and pharmaceutical compositions
  • Anti-obesity strain of lactic acid bacteria and uses in food and pharmaceutical compositions
  • Anti-obesity strain of lactic acid bacteria and uses in food and pharmaceutical compositions

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Example 1: Morphology and general properties of anti-obesity lactic acid bacteria.

[0030] The source of isolation is human breast milk, collected from parturient women in Tainan area. According to the 16S rDNA sequence analysis and the API bacterial identification system analysis results, the taxonomic characteristics of the strains were confirmed. It was found that the two strains of lactic acid bacteria described in the present invention were Bifidobacterium longum and Bifidobacterium breve respectively. The characteristics of the above strains in morphology and general properties are listed in Table 2:

[0031] Table 2 Morphology and general properties of the strains

[0032]

[0033]

[0034]

Embodiment 2

[0035] Example 2: The mice were fed once with a high-concentration bacterial strain, and sacrificed after 14 days. Compared with the control group, changes in the heart fat weight of the mice were observed.

[0036] Check that the fat-reducing lactic acid bacteria strain of the present invention-Bifidobacterium longum CP-9 strain CCTCC NO:M2014588 reduces the weight of the surrounding fat of the heart, which is to feed the high-concentration strain once, sacrifice it after 14 days of observation, dissect and weigh The weight of fat around the heart is used to verify the fat-reducing ability of the above strains. The experimental steps are as follows:

[0037] 1. Animals were tested when they were 5-6 weeks old.

[0038] 2. The animals were randomly divided into two groups, one group was fed with drinking water, and the other group was fed with bacteria powder water.

[0039] 3. After re-dissolving in water with an appropriate amount of high-concentration bacterial powder, gi...

Embodiment 3

[0053] Example 3: The anti-obesity lactic acid bacteria are used in the pre-test of human clinical trials.

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Abstract

An anti-obesity strain of lactic acid bacteria and uses in food and pharmaceutical compositions are disclosed. Isolated lactic acid bacteria strains which are CP-9 (Bifidobacterium longum) and/or bv-77 (Bifidobacterium breve) are provided. The present invention provides the novel strains of lactic acid bacteria and novel compositions having fat reducing/weight reducing capabilities containing the present strains. The compositions may be used in the form of food or pharmaceutical compositions.

Description

technical field [0001] The present invention relates to a lactic acid bacteria strain and its application in food composition and medical composition, especially an anti-obesity lactic acid bacteria strain and its application in food composition and medical composition. Background technique [0002] Fat is a necessary component in the human body, but excessive fat content will cause damage to the human body. In countries where the national economy is taking off more and more, the obesity problem will only increase. Therefore, from the perspective of the Asian region, China will be the next country where the obesity problem will increase significantly. [0003] In addition, Taiwan has now become the "fattest country in Asia". Among citizens over the age of 18, 51.1% of men and 35.8% of women are overweight, and the proportion is still rising. The overweight age group is also declining year by year, and the proportion of overweight primary and middle school students has risen...

Claims

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Application Information

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IPC IPC(8): C12N1/20A61K35/745A61P3/04A23L1/30C12R1/01
Inventor 谢佩珊郭仲伟蔡宜钧邱美菁
Owner 安徽锦乔生物科技有限公司
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