Drug eluting balloon with preferred drug orientation to improve drug transfer efficiency

A drug and balloon technology, applied in the direction of balloon catheters, catheters, etc., can solve problems such as low drug delivery efficiency

Inactive Publication Date: 2016-10-12
BOSTON SCI SCIMED INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Therefore, there will be low drug delivery efficiency

Method used

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  • Drug eluting balloon with preferred drug orientation to improve drug transfer efficiency
  • Drug eluting balloon with preferred drug orientation to improve drug transfer efficiency
  • Drug eluting balloon with preferred drug orientation to improve drug transfer efficiency

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Embodiment Construction

[0021] While embodiments of the invention may take many forms, specific embodiments of the invention are described in detail herein. The description is an illustration of the principles of the invention and is not intended to limit the invention to the specific embodiments described.

[0022] For the purposes of the present invention, a crystal extending perpendicular to a surface is characterized as having a longitudinal axis which is perpendicular to the surface in the region of the surface from which the crystal extends. This means that the longitudinal axis of the crystal is perpendicular to any tangent to the surface at the point where the crystal extends from it. In addition, the term "within n° of an angle" means within ±n° of the angle.

[0023] figure 1 The distal end of the balloon catheter, indicated generally at 100, is shown. Balloon catheter 100 includes balloon 104 shown in an inflated state. Balloon 104 extends from catheter 108 . Balloon 104 includes a b...

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Abstract

A catheter comprises a medical balloon having a drug coating. The drug coating comprises drug crystals on a surface of the balloon. The majority of the drug crystals on the surface of the balloon are oriented drug crystals which extend within 5 degrees of a predetermined, non-zero common angle relative to the surface of the balloon from which the crystals extend.

Description

[0001] Cross References to Related Applications [0002] This application claims the benefit of and priority to US Provisional Patent Application Serial No. 61 / 923,068, filed January 2, 2014, which is incorporated herein by reference in its entirety. [0003] Statement Regarding Federally Funded Research [0004] Not applicable. Background technique [0005] Drug-coated balloons may include crystalline drug or other types of drug particles disposed on the balloon. Drug crystals or drug particles are usually oriented randomly on the balloon surface. However, part of the coating is lost during routing of the balloon and part of the coating is lost during deployment. This results in a relatively small percentage (between 1% and 10%) of the drug being deposited on arteries or other blood vessels. Therefore, there may be low drug delivery efficiency. [0006] It is believed that solid particles deposited on the walls of arteries or other blood vessels have three possible ou...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L29/14A61L29/16
CPCA61L29/14A61L29/16A61L2300/416A61L2300/63A61M25/1029A61M2025/1031
Inventor 红霞·曾言-莱恩·陈史蒂文·L·坎加斯
Owner BOSTON SCI SCIMED INC
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