23 results about "Drug transfer" patented technology

The invention belongs to the technical field of medical instruments. The invention discloses a drug coating balloon catheter and a preparation method thereof. In one aspect, a drug coated balloon catheter includes a catheter with a balloon; a drug coating at least comprising an inner coating and an outer coating is arranged on the outer wall of the balloon, and the inner coating and the outer coating are provided with drug active ingredients and different carriers respectively; when the balloon is expanded, the inner coating and the outer coating are separated from the balloon through the state change of the temperature-sensitive carrier of the inner coating under the body temperature environment of a patient and the hydration effect, and the outer coating is used for promoting corresponding active pharmaceutical ingredients to be transferred into target tissues through the carrier of the outer coating when the outer coating is separated from the balloon. On the other hand, the invention provides a preparation method of the drug coating balloon catheter. The preparation method has the advantages that the adhesiveness of the drug coating on the balloon can be effectively improved so as to reduce the delivery loss, and the release rate of the drug coating on diseased tissues can be improved so as to improve the drug transfer capacity.

A method for injecting a therapeutic agent into a patient's skin or mucosa. The method uses a vial containing a therapeutic agent and a syringe containing a diluent comprising an aqueous solution. Attach a closed system drug transfer (CSDT) device to the syringe. Attach the CSDT device to the vial. Transfer the diluent from the syringe into the vial through the CSDT. Mix the diluent and the therapeutic agent to make a therapeutic agent solution mixture. Fill the syringe with the therapeutic agent solution mixture. The concentration of the therapeutic agent in the therapeutic agent solution mixture is ≤ 5 mg / ml. Inject the therapeutic agent solution mixture into skin or mucosa of the patient. Also disclosed are other injection methods and injection kits.

The utility model relates to the field of medicament proportioning, and discloses a medicament quantitative proportioning device, which comprises a fixed plate and a mixing tank, the top end of the fixed plate is fixedly connected with the mixing tank, the two sides of the top end of the mixing tank are respectively provided with an inlet, and the two sides above the mixing tank are respectively provided with a class I medicament storage tank and a class II medicament storage tank. Metering valves are respectively arranged between the mixing tank and the I-type medicament storage tank and between the mixing tank and the II-type medicament storage tank. According to the drug quantitative proportioning device, the first class I drug original tank, the class I drug transfer pump and the class II drug transfer pump are all electric pumps, so that during continuous feeding, even if drugs in one group of original tanks are used up, the other group of original tanks can be used for continuously pumping the drugs, the device operation is not influenced, the conditions of shutdown and waiting cannot occur in the production process, and the production efficiency is improved. And the metering valve can accurately control the volume of the medicament fed into the mixing tank each time according to a set proportion, so that accurate proportioning is realized, and the problems of poor proportioning efficiency and poor continuity are solved.

The medicine transfer mechanism comprises an adsorption assembly and a driving assembly, the adsorption assembly comprises a plurality of vacuum suction cups externally connected with negative pressure equipment, and each vacuum suction cup comprises a plurality of first suction cups and a third suction cup with the adsorption area larger than the sum of the adsorption areas of the first suction cups; the driving assembly is connected with the adsorption assembly and drives the adsorption assembly to move in the vertical direction and / or the horizontal direction. The medicine transfer mechanism is provided with a plurality of relatively small vacuum suction cups, the total adsorption area is guaranteed by increasing the number, so that the adsorption effect is guaranteed, and the situation that the number of the suction cups is not enough, the suction cups act on the edge positions of medicine boxes, consequently, enough adsorption force cannot be provided, and the medicine boxes cannot be correctly adsorbed and carried is avoided. Secondly, the sizes of the vacuum suction cups are different, the third suction cup serves as the main suction cup, the suction area of the third suction cup is large, and the situation that a medicine box with the small size is clamped in a gap between the adjacent vacuum suction cups due to the improper action position is avoided.

Provided is a balloon catheter with which a drug transferred from a balloon to a blood vessel wall does not easily separate from the blood vessel wall.　This balloon catheter has a balloon (20). The balloon (20) has a balloon body part (30) having a longitudinal direction x and a radial direction y, and a drug layer (40) that is disposed outward of the balloon body part (30) in the radial direction y and contains a drug. The drug layer (40) has a radial crystal group (42) including a plurality of columnar crystals (41) of the drug arranged radially. In a cross section in the longitudinal direction x, the radial crystal group (42) has a fan shape, and the central angle θ of the fan shape exceeds 180°.

The present invention provides a balloon dilatation catheter, belonging to the technical field of balloon dilatation catheters; the balloon dilatation catheter comprises a catheter body, wherein a balloon body for dilating a stenotic site is provided at the distal end of the catheter body, and an operating handle for filling and releasing a filling medium into the balloon body is provided at the proximal end; a flow channel for blood flow is formed on the balloon body and / or between the balloon body and the outer side wall of the catheter body along the axial extension direction of the catheter body; during operation, the balloon body is inflated to treat the stenotic site, and the blood flow in the stenotic site continues to flow through the flow channel; the balloon dilatation catheter is mainly used to solve the technical problems in the prior art of insufficient distal blood supply caused by blood flow blockage during balloon expansion, and insufficient contact time between the balloon and the blood vessel wall affecting the drug transfer effect.

This invention relates to a non-whole-piece drug transfer box for use in a drug dispensing machine. The box includes a main body with numerous temporary storage holes penetrating its upper and lower surfaces. Each storage hole corresponds to a specific drug box on a dispensing device. A base plate is slidably connected to the bottom of the main body, sliding radially along the storage holes. The base plate supports the lower ends of all storage holes and can slide away from them. A handle is provided at one end of the base plate along its sliding direction. This invention solves the technical problem of errors in drug dispensing from the dispensing devices of current drug dispensing machines, which affects the efficiency of the machine.

The invention discloses a microneedle raw material composition, a microneedle, a microneedle patch, a drug eluting balloon and a preparation method and application thereof. The composition comprises a compound as shown in a formula I which is described in the specification. The microneedle comprises: a needle body; the needle body is prepared from a first raw material, and the first raw material comprises the composition. The drug eluting balloon comprises an expansion balloon, and the microneedle is fixed on the surface of the expansion balloon; the microneedle patch comprises the microneedle. The composition disclosed by the invention can be used for preparing the microneedle with photoresponsiveness, the needle body of the microneedle can be quickly separated from the bottom under the irradiation of near-infrared light, the medicine pre-loaded in the needle body is transferred to tissues, and the medicine delivery efficiency is high. According to the drug eluting balloon disclosed by the invention, mechanical force generated by balloon dilatation is utilized to accurately pierce a microneedle into a pathological tissue, so that local efficient delivery of a drug is realized; through the photoresponsiveness of the microneedle, the drug-loaded particles are transferred to the target tissue, the drug transfer rate is high, systematic toxicity is avoided, and the drug utilization degree is high. # imgabs0 #

The utility model discloses an electronic booster for a medicine transfer cart in a hospital, which comprises a boosting unit, the boosting unit comprises a U-shaped frame, two vertical plates I and two vertical plates II are fixed at the bottom of the U-shaped frame, a rotating shaft I is rotatably connected in the vertical plates I, and a roller I is mounted at one end of the rotating shaft I. When the medicine transfer cart is used, the medicine transfer cart is moved into the U-shaped frame, then the baffle and the U-shaped frame are fixed, then the screw rod is rotated, the medicine transfer cart is fixed in the U-shaped frame through the abutting plate, then the hook-and-loop fastener hook face and the hook-and-loop fastener loop face are arranged on a handle of the medicine transfer cart in a sleeving mode, the hook-and-loop fastener hook face and the hook-and-loop fastener loop face are bonded, and the medicine transfer cart is placed on the U-shaped frame. The control button is installed on the handle of the medicine transfer cart, the double-shaft motor can be controlled to be started and stopped through the control button, the double-shaft motor is started to drive the second rotating shaft to rotate, the second rolling wheels can be driven to roll, the medicine transfer cart is driven to move in an auxiliary mode, and the power assisting device can be detached and can be conveniently applied to different medicine transfer carts.

The utility model discloses a medicine transfer device for medicine quality management, which relates to the technical field of medicine quality management and comprises a transport frame, four transport wheels and a power supply module, the four transport wheels are respectively mounted on the lower wall surface of the transport frame, and the power supply module is mounted on the lower wall surface of the transport frame. An auxiliary grip is installed on the front wall face of the transporting frame, a guide threaded rod is installed on the upper wall face of the transporting frame, the outer wall face of the guide threaded rod is sleeved with a limiting structure, a temperature adjusting compressor is installed on the upper wall face of the transporting frame, and four limiting holes are formed in the upper wall face of the temperature adjusting compressor. Transfer structures are installed in the four limiting holes. Through cooperation of four limiting rods and four limiting holes, the transfer cabinet is prevented from transversely moving during transfer, through cooperation of a limiting cover plate and a limiting threaded sleeve, the transfer cabinet is prevented from jolting up and down during transfer, the gas temperature loss speed is reduced through a plurality of gas inlet channels, and cold and hot air is evenly discharged into the transfer cabinet.

A medical device cap that protectively surrounds a medical device component for disinfection purposes and includes an identification element that can record and transmit pertinent information of the medical device cap and the medical device component is disclosed. The medical device cap enables documentation of instances when the cap is used and promotes stronger compliance with the use of medical device caps for applications involving disinfection of a medical device component such as an IV access port or a luer tip. Use of the medical device cap results in better compliance and monitoring of the use of such caps and leads to reduced incidence of CRBSI infections related to medical device component contamination. In one embodiment, the medical device cap enables automated real-time electronic documentation of when the cap is applied, while also documenting duration of application and tracking of device for inventory management.

This invention relates to a balloon catheter that allows for the aspiration of drug solution from outside the balloon catheter via a return channel. This ensures that the blocked target area maintains a high drug concentration, thereby reducing drug loss during delivery and perfusion, improving the efficiency of drug transfer to the target tissue, and reducing the risk of thrombosis.

The invention discloses a store medicine supply method and device based on patient behavior analysis and a storage medium, and the method comprises the steps: obtaining the medicine purchasing behavior data of a patient in each historical time period, and determining the medicine transfer number between stores in adjacent historical time periods; constructing a first graph structure by taking each store in each historical time period as a first node and taking a medicine transfer trend as a first edge; inputting the first graph structure into a graph neural network model, and performing iterative updating on the first graph structure by using the graph neural network model to generate a second graph structure; based on each second node feature and each second edge feature of the second graph structure, determining a plurality of third node features and a plurality of third edge features of the current time period; and inputting the third node features corresponding to each store in the current time period into the first prediction model, inputting a plurality of third edge features corresponding to each store into the second prediction model, and predicting to obtain a target drug supply quantity corresponding to each store in the current time period.

The invention relates to the technical field of medical instruments, in particular to a medical medicine transferring and storing device which comprises a transferring frame, a handle is fixedly connected to one side of the transferring frame, first bearing pieces are fixedly connected to the two sides of the upper surfaces of the two layers of the transferring frame correspondingly, and first telescopic rods are fixedly connected to the upper surfaces of the two sides of each first bearing piece correspondingly; a first pressing piece is fixedly connected between the top ends of the first telescopic rods, first springs fixedly sleeve the outer surfaces of the first telescopic rods, a plurality of moving pieces are slidably connected to the two sides of the upper surfaces of the two layers of the transfer frame, and second bearing pieces are rotatably connected between the inner sides of the moving pieces; second telescopic rods are fixedly connected to the upper surfaces of the two sides of the second bearing piece, a second downward pressing piece is fixedly connected between the top ends of the second telescopic rods, the two ends of the nutrition bag can be fixed when the first downward pressing piece and the second downward pressing piece extrude downwards, and the situation that the nutrition bag slides due to vibration or inclination in the transferring process is effectively prevented; and the nutrition bag can be kept at the initial position.

The invention relates to the field of medical instruments, in particular to a liquid medicine transfer device which comprises an injector, a three-way connector communicated with the injector, a bag tube and a bottle tube which are communicated with the three-way connector and can be squeezed and blocked, a bag puncture needle communicated with the bag tube and can be communicated with an infusion bag, and a bottle puncture needle communicated with the bottle tube and can be communicated with a medicine bottle. In the medicine dispensing process, liquid medicine does not make contact with air, the liquid medicine is not prone to leakage, and the possibility that the liquid medicine is polluted or the leakage of the liquid medicine affects the health of medical staff is reduced.

A vial adapter for accessing a vial is provided herein. The vial adapter includes a base having a distal side and a proximal side with a base lumen extending between the distal side and the proximal side. The vial adapter further includes: a first connector positioned at a distal side of the base and configured to couple with a vial; a second connector positioned on a proximal side of the base and configured to couple with a fluid container; and a lancet element extending distally from the base and configured to pierce a stopper of a vial, the lancet element defining a lancet lumen in fluid communication with the base lumen. The first connector is positioned on the lancet element and includes an arm structure configured to engage with the stopper to secure the vial adapter to the vial.

The utility model discloses a novel medicine transfer cart, which relates to the technical field of clinical medicine and comprises a bottom plate, a storage tray is arranged at the upper end of the bottom plate, a storage box is fixed at the bottom end of the storage tray, a first side seat and a second side seat are respectively fixed on two sides of the storage box, and a support column is fixed at the lower end of the first side seat. A plurality of carrying blocks are rotationally connected to the outer side of the supporting column, a tray is fixed to one side of each carrying block, a limiting block is fixed to the side, away from the corresponding carrying block, of each tray, a hollow screw cylinder is rotationally connected to the upper end of the second side base, a screw is in threaded connection with the inner side of the hollow screw cylinder, a supporting rod is fixed to the upper end of the screw, and a hook is fixed to the upper end of the supporting rod. According to the novel medicine transfer cart, through the overall structural matching design, the hooks can be conveniently moved upwards to be unfolded to hang various medical medicines, and after the hooks are moved upwards, the trays can be conveniently turned over with the supporting column as the axis to be taken out to be cleaned.

To efficiently provide cassettes to users. [Solution] The main unit (2) comprises a cassette shelf (21), a transfer cassette holding unit (231) that temporarily holds cassettes (Ca) taken out of the cassette shelf and transferred to the drug transfer unit (32), a receiving cassette holding unit (232) that temporarily holds cassettes returned from the drug transfer unit to the receiving cassette shelf, and a main unit cassette transfer unit (22) that transfers cassettes between the cassette shelf and the transfer cassette holding unit, and between the cassette shelf and the receiving cassette holding unit.

This invention belongs to the field of medical device technology. This invention discloses a drug-coated balloon catheter and its preparation method. On one hand, a drug-coated balloon catheter includes a catheter with a balloon; the outer wall of the balloon is provided with a drug coating comprising at least an inner coating and an outer coating, both the inner and outer coatings carrying active pharmaceutical ingredients and different carriers; when the balloon inflates, the inner coating, together with the outer coating, detaches from the balloon under the influence of the patient's body temperature and hydration through a state change caused by the temperature-sensitive carrier of the inner coating; the outer coating, upon detachment from the balloon, facilitates the transfer of the corresponding active pharmaceutical ingredient into the target tissue via its carrier. On the other hand, a method for preparing a drug-coated balloon catheter is provided. This invention has the advantages of effectively improving the adhesion of the drug coating to the balloon to reduce delivery loss and increasing the release rate of the drug coating on diseased tissue to enhance drug transfer capability.

A drug transfer device includes: a housing; a vial attachment configured to secure the drug transfer device to a vial; a vial transfer member defining a channel; a cannula received within the housing, wherein the cannula is in fluid communication with the channel of the vial transfer member and has a first end and a second end positioned opposite the first end; a sealing device positioned within the housing, wherein the sealing device is movable within the housing between a first position and a second position, wherein in the first position the cannula is isolated from the first end of the housing, and in the second position the cannula is configured to be in fluid communication with a mating connector received at the first end of the housing; and a connecting member defining a channel in fluid communication with the channel of the vial transfer member, wherein the connecting member is configured to receive the mating connector.

A drug delivery system (10) for delivering a therapeutic agent into a lumen while allowing fluid perfusion. The illustrative drug delivery system includes: an elongated inner shaft (12) extending proximally to distally and including a lumen (24) extending proximally to distally therefrom; and an elongated outer shaft (14) extending proximally to distally and including a lumen (30) extending proximally to distally therefrom. The elongated outer shaft is disposed on the elongated inner shaft and is axially movable relative to the elongated inner shaft. A self-expanding drug delivery device (16) includes a plurality of longitudinally extending struts (42) and is movable between a radially collapsed configuration and a radially expanded configuration. A drug coating (54) is disposed on at least a portion of the radially outward surfaces of the longitudinally extending struts.

The present invention discloses a double butterfly valve aseptic drug transfer system and a aseptic drug transfer method, which relate to the field of pharmaceutical technology. The present invention comprises a reversible drug storage tank, an active butterfly valve, a passive butterfly valve, a powder storage tank and a sterile liquid medicine storage bag. The discharge port of the reversible drug storage tank is connected to the active butterfly valve via a first connecting piece, the active butterfly valve is connected to the passive butterfly valve via a second connecting piece, the passive butterfly valve is connected to the feed port of the powder storage tank via a third connecting piece, the discharge port of the powder storage tank is provided with a diaphragm valve 1, and the discharge port of the powder storage tank is connected to the sterile liquid medicine storage bag. The present invention adopts a double butterfly valve design to establish an aseptic connection between the reversible drug storage tank and the powder storage tank, and the clamp connection has strong reliability, simple structure, low operation complexity, strong versatility, high flexibility and low cost.

Presented herein are a robotic system that is configured for compounding and preparation of medications comprising non-hazardous drugs and a vented drug vial adapter. The robotic system comprises: a laminar flow cabinet; and at least one robotic arm. The vented drug vial adapter is designed to connect a drug vial to another component of a drug transfer system. The adapter comprises a hydrophobic filter that prevents passage of liquid while allowing air to pass through it and a vent hole to the atmosphere. The vent hole is located above the filter thereby allowing equalization of the internal pressure while preventing the drug from contaminating the atmosphere.