Method for extracting total flavonoids from boxthorn leaves

Abstract

The invention discloses a method for extracting total flavonoids from boxthorn leaves, and belongs to the field of natural medicine effective component extraction. The method comprises the steps that boxthorn leaves are adopted as raw materials, and a product obtained through extraction, concentration, separation, purification and drying contains rutin, quercetin, kaempferol and isorhamnetin. The preparation has the effects of good free radical resistance, oxidation resistance, aging resistance, blood fat reduction and the like, and the preparation can be widely applied to functional foods and medicine and health products. In the preparation process, ethyl alcohol is used as an extraction solvent and an eluent, and macroporous resin is adopted as a separating material. The adopted solvent is safe, free of toxicity, low in price and capable of being recycled. The production process is safe, easy, convenient to implement, free of environment pollution, easy to control and suitable for large-scale industrial production, and meanwhile further has the advantages of being high in flavone extraction rate and purity and the like.

Description

technical field [0001] The invention relates to a method for extracting total flavonoids from wolfberry leaves, in particular to a method for separating total flavonoids from wolfberry leaves by high-efficiency reflux concentration extraction-column chromatography, and belongs to the field of effective component extraction of natural medicinal materials. Background technique [0002] Extracting chemical components from plants for medicinal purposes has a history of 5,000 years in the traditional medicine of the motherland. Traditional extraction methods can be divided into two categories according to the different energy requirements of the extraction process. One is the heating extraction method, which mainly includes different methods such as decoction extraction, reflux extraction and Soxhlet extraction; the other is the soaking extraction method, which mainly includes dipping extraction and percolation extraction. Traditional extraction methods have disadvantages such a...

AI Technical Summary

Problems solved by technology

The water extraction method is low in cost and safe, but the extraction efficiency is low and it contains many impurities, which brings many difficulties to the subsequent separation

The alkaline solution used in alkaline water or alkaline dilute alcohol extraction method is dilute sodium hydroxide and lime water (calcium hydroxide aqueous solution). The leaching ability of sodium hydroxide aqueous solution is high, but there are many impurities that are not conducive to purification. Calcium will combine with some flavonoids to form insoluble substances, reducing the leaching rate

The microwave method overcomes some defects in the above method, but during the extraction process, the thermal effect of microwave will lead to the degradation of some thermal substances in the extract, which seriously affects the activity of the extract, and also limits the wide application of this method

Ultrasonic extraction time is short and efficient, but it is difficult to achieve large-scale industrial production