Compound massage essential oil for ovary protection

An essential oil and compound technology, applied in skin care preparations, pharmaceutical formulations, cosmetic preparations, etc., can solve problems such as damage, obvious pain, and incomplete mechanism.

Inactive Publication Date: 2016-11-16
广州春本龙脑生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

With the increasing incidence of tumors, especially in women, radiotherapy and chemotherapy can cause serious or even irreversible damage to the structure and function of women's ovaries, resulting in premature ovarian failure and related infertility. The existing ovarian protection drugs are mainly The endocrine drug gonadotropin-releasing hormone agonist (GnRHa), commonly used is Dipherene, which can inhibit ovarian function and protect the ovary, but the cost is high, and there will be obvious pain when used, and it can protect the ovary. The mechanism of action is not completely clear, and there are certain adverse reactions; amifostine can be used as an adjuvant drug for ovarian cancer, but adverse reactions such as transient hypotension may occur when taking the drug, so borneol camphor essential oil and grape seed oil are used The combination of rose essential oil and massage can be a good auxiliary method for ovarian protection, and it can also reduce the pain of drug injection for patients

Method used

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  • Compound massage essential oil for ovary protection
  • Compound massage essential oil for ovary protection

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Every 1000mL of the massage essential oil for treating breast lobular hyperplasia contains 120-180mL borneol camphor essential oil, 800-850mL grape seed oil PEG-8 ester, 20-30mL rose essential oil and 8-12mL azone. Preferably, every 1000 mL of the massage essential oil contains 150 mL of borneol camphor essential oil, 815 mL of grape seed oil PEG-8 ester, 25 mL of rose essential oil and 10 mL of azone.

[0015] The preparation method of the massage essential oil is as follows: heat the grape seed oil PEG-8 ester slightly to 40°C, then filter it with double-layer gauze, and when the temperature of the filtered grape seed oil PEG-8 ester reaches 25°C, slowly add borneol camphor Essential oil, rose essential oil, azone, stir (about 3min) evenly to get the compound massage essential oil for ovarian protection. Fill it statically in a 20mL brown glass bottle, seal it, and store it for later use. Among them, the best extraction process of borneol camphor is extraction by ste...

Embodiment 2

[0017] The effect of massage essential oil described in embodiment 1 on acetic acid-induced mouse writhing

[0018] In this experiment, we observed the effect of massage essential oil on the writhing response of mice induced by acetic acid, and evaluated the analgesic effect of massage essential oil.

[0019] 1. Experimental materials

[0020] 1.1 Drugs

[0021] 1.1.1 Test product: massage essential oil described in Example 1.

[0022] 1.2 Experimental animals

[0023] 1.2.1 40 ICR mice, half male and half female, SPF grade, weighing 18-22 g, animal certificate number: No. 43004700011566, purchased from Hunan Slack Jingda Experimental Animal Co., Ltd., experimental animal production license number: SCXK ( Xiang) 2011-0003; they were raised in a barrier environment at the Hunan Drug Safety Evaluation and Research Center, and the experimental animal use license number: SYXK (Xiang) 2010-0008.

[0024] 1.3 Reagents

[0025] Castor oil (batch number: 20110503, product of Shan...

Embodiment 3

[0039] The effect of massage essential oil described in Example 1 on hot plate-induced mouse writhing

[0040] This experiment observes the effect of massage essential oil on the writhing response of mice induced by hot plate, and evaluates the analgesic effect of massage essential oil.

[0041] 1. Experimental materials

[0042] 1.1 Drugs

[0043] 1.1.1 Test product: massage essential oil described in Example 1.

[0044] 1.2 Experimental animals

[0045] 1.2.1 40 ICR mice, female, SPF grade, weighing 18-22 g, animal certificate number: No. 43004700011566, purchased from Hunan Slack Jingda Experimental Animal Co., Ltd., experimental animal production license number: SCXK (Xiang) 2011-0003; Breeding in the barrier environment of Hunan Drug Safety Evaluation Research Center, experimental animal use license number: SYXK (Xiang) 2010-0008.

[0046] 1.3 Reagents

[0047] Castor oil (batch number: 20110503, product of Shanghai Shanpu Chemical Co., Ltd.).

[0048] 1.4 Instrumen...

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Abstract

The invention discloses compound massage essential oil for ovary protection. Every 1000mL of essential oil contains 120-180mL of cinnamomum camphora essential oil, 800-850mL of grape seed oil PEG-8 ester, 20-30mL of rose essential oil and 8-12mL of azone. In the essential oil, cinnamomum camphora essential oil does not have the ovary protection effect, but after the cinnamomum camphora essential is transdermally absorbed, dextro borneol can dilate blood vessels, the blood flow rate in a unit time can be reinforced, discharge of toxin in a body can be benefited while the lower abdominal blood flow speed of a female is accelerated; and rose essential oil is the main ingredient for protecting ovary, camphol in the cinnamomum camphora essential oil can be used for promoting absorption of the essential oil, and the grape seed oil can be used for improving the skin condition. The compound massage essential oil is beneficial to blood circulation when being used for massaging.

Description

technical field [0001] The invention specifically relates to a compound massage essential oil for ovarian protection. Background technique [0002] The compound with the highest concentration in camphor leaf essential oil is borneol. The essential oil components extracted from this chemical type camphor tree are d-borneol (d-borneol, content as high as 81.78%), 1,8-cineole, linalool, á-terpineol, limonene, -carene, p-cymene, á-terpinene, - Monoterpenes (alcohols) such as pinolene and oxalene, -Elemene, -Sesquiterpenes such as caryophyllene. Borneo camphor is a new chemical type of camphor tree discovered and named for the first time by Ji'an Forestry Science Research Institute of Jiangxi Province. An excellent family of borneol camphor "Shuishang No. 18" was discovered and selected. Its leaves contain more than 1.90% of essential oils, and the essential oil is Zhonglong The brain content is more than 80.00%, and has wide application prospects. The borneol extracted...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/92A61K8/49A61K36/738A61Q19/00A61P15/00A61K31/045
CPCA61K8/922A61K8/4906A61K31/045A61K36/738A61Q19/00A61K2300/00
Inventor 谭桂山徐康平曾光龙晓明杨尚真
Owner 广州春本龙脑生物科技有限公司
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