Unlock instant, AI-driven research and patent intelligence for your innovation.

covered microneedle array

A technology of microneedle and covering relationship, applied in the field of microneedle array

Active Publication Date: 2018-03-27
SORRENTO THERAPEUTICS INC
View PDF8 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, conventional subcutaneous (often intramuscular) drug delivery via needles is used to deliver large amounts of drug at once, thus often creating a peak in the bioavailability of the drug

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • covered microneedle array
  • covered microneedle array
  • covered microneedle array

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0029] Exemplary embodiments are described below and illustrated in the drawings, wherein like numerals indicate like parts throughout the several views. The described embodiments provide examples and should not be construed as limiting the scope of the invention. Other embodiments, as well as modifications and improvements of the described embodiments will occur to those skilled in the art, and all such other embodiments, modifications and improvements are within the scope of the invention.

[0030] figure 1 is a micrograph of a portion of a membrane-draped microneedle assembly that can be used as part of a drug delivery device according to a first embodiment of the present disclosure. see also figure 2 can best be understood in figure 1 At least some of the underlying shape of the microneedle assembly or array 12 is visible, but the actual surface of the microneedle array is substantially hidden from view in figure 1 Behind the opaque drape film 14 in. Alternatively, t...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
lengthaaaaaaaaaa
lengthaaaaaaaaaa
Login to View More

Abstract

The configuration of the elongated pores in the membrane draping the microneedle assembly can be controlled by controlling the manner in which the pores are formed and / or by controlling the manner in which the membrane is draped. At least a portion of the membrane may be spaced apart from the microneedles such that a gap is defined between the membrane and the microneedles. The gap may be configured to at least partially control the formation of the elongated aperture. The shape of the gap may optionally be defined at least in part by pleats in the membrane. Any pleats can be aligned in a predetermined manner. The elongated aperture may be formed by a piercing member passing through an aperture in the microneedle assembly prior to piercing the membrane. The piercing member may be a laser beam.

Description

[0001] Cross references to related patent applications [0002] This application claims the benefit of U.S. Provisional Patent Application No. 61 / 996,148, filed April 30, 2014. [0003] Incorporate by reference [0004] WO 2012 / 020332 to Ross, WO 2011 / 070457 to Ross, WO 2011 / 135532 to Ross, US 2011 / 0270221 to Ross, US 2013 / 0165861 to Ross, US to Baker et al. Provisional Patent Application No. 61 / 996,148 is hereby incorporated by reference in its entirety. technical field [0005] The subject matter generally relates to microneedle arrays that can be used to deliver pharmaceutical formulations to patients through the skin. Background technique [0006] A number of devices have previously been developed to deliver drugs and other pharmaceutical compounds transdermally using arrays of microneedles. Microneedles have the advantage of causing less pain to the patient than larger conventional needles. Furthermore, conventional subcutaneous (often intramuscular) drug delivery v...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61M37/00
CPCA61M2037/0038A61M2037/0053A61B5/150022A61B5/150435A61B5/150984A61M37/0015B29C35/0805B29L2031/753
Inventor A·T·贝克E·D·加斯比R·F·罗斯
Owner SORRENTO THERAPEUTICS INC