Application of nepodin-8-O-beta-D-glucopyranoside to preparation of antidepressant drugs

A technology of glucopyranoside and ruminol, applied in the application field of ruminol-8-O-β-D-glucopyranoside in the preparation of antidepressant drugs, can solve the withdrawal syndrome, large side effects, Slow effect and other problems, to achieve the effect of reducing immobility time and antidepressant effect

Active Publication Date: 2016-12-14
KUNMING INST OF BOTANY - CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although these drugs have certain curative effects in clinical application, they have large side effects, slow onset of effect, and easy to produce withdrawal syndrome after drug withdrawal, so it is still necessary to develop new antidepressant drugs

Method used

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  • Application of nepodin-8-O-beta-D-glucopyranoside to preparation of antidepressant drugs
  • Application of nepodin-8-O-beta-D-glucopyranoside to preparation of antidepressant drugs
  • Application of nepodin-8-O-beta-D-glucopyranoside to preparation of antidepressant drugs

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Refer to the invention patent application No. 201010529240.2 for the sorrel-8-O-β-D-glucopyranoside prepared by adding the excipient at a ratio of 1:5-1:10 , Granulated tablet.

Embodiment 2

[0019] Refer to the invention patent application No. 201010529240.2 for the sorrel-8-O-β-D-glucopyranoside prepared by adding the excipient at a ratio of 1:1-1:10 , made into capsules according to a conventional method.

Embodiment 3

[0021] Refer to the sorrel-8-O-β-D-glucopyranoside prepared by the invention patent application whose application number is 201010529240.2, and make an oral liquid according to a conventional method.

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Abstract

The invention provides nepodin-8-O-beta-D-glucopyranoside and an application of extract products containing nepodin-8-O-beta-D-glucopyranoside to preparation of antidepressant drugs, as well as an application of epodin-8-O-beta-D-glucopyranoside to preparation of foodstuffs with antidepressant functions. The invention provides the antidepressant drugs containing nepodin-8-O-beta-D-glucopyranoside and derivatives thereof as well as medicinal carriers or excipients.

Description

Technical field: [0001] The present invention relates to Nepodin-8-O-β-D-glucopyranoside (Nepodin-8-O-β-D-glucopyranoside) and its extracts or components in the preparation of antidepressant pharmaceutical preparations or functional foods Applications. Background technique: [0002] Depression is a typical emotional disease, which may be related to congenital, but acquired environment is also very important, so there is a high incidence of depression in high-paced society. Depression not only brings serious physical and mental distress to the patient, but also brings many burdens to the family and society. Psychological intervention for depression has a certain effect, but drug treatment still dominates. Antidepressants developed according to the pathogenesis of depression and currently in clinical use include monoamine oxidase inhibitors, tricyclic antidepressants, tetracyclic antidepressants, selective serotonin reuptake inhibitors, selective serotonin and depressant No...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/704A61P25/24A23L33/10
CPCA23V2002/00A61K31/704A23V2200/30
Inventor 程永现张艳娇卜庆华田磊桑秋
Owner KUNMING INST OF BOTANY - CHINESE ACAD OF SCI
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