Synthetic drug for treating gastroenteritis and preparation method thereof

A technology for synthesizing drugs and gastroenteritis, which is applied in the field of synthetic drugs for treating gastroenteritis and its preparation, which can solve problems such as dehydration and electrolyte disturbance, achieve efficient and rapid preparation, improve utilization rate, and have less toxic and side effects

Inactive Publication Date: 2016-12-14
成都威迪视特生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In healthy adults, gastroenteritis usually causes only discomfort and inconvenience without serious consequences, but can lead to life-threatening dehydration and electrolytes in very ill, debilitated, young or elderly patients disorder

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A synthetic medicine for treating gastroenteritis. A traditional Chinese medicine composition for gastroenteritis that can treat both symptoms and root causes is prepared. The prepared synthetic medicine has little toxic and side effects in clinical application and will not cause gastrointestinal mucosal damage. damage; the designed preparation method can efficiently and quickly prepare synthetic drugs, and can effectively ensure that the useful substances of various drug components are efficiently utilized, and can improve the utilization rate of drug components on the basis of existing preparation technologies. It is made from the following raw materials in parts by weight: 8-12 parts of astragalus, 10-14 parts of coix seed, 8-12 parts of Codonopsis pilosula, 9-15 parts of poria cocos, 7-12 parts of blood charcoal, red stone 9~11 parts of fat, 6~15 parts of white peony, 4~8 parts of Atractylodes charcoal, 4~8 parts of tangerine peel charcoal, 5~7 parts of Bupleurum, 5~...

Embodiment 2

[0025] This embodiment is further optimized on the basis of the above-mentioned embodiments. In order to better realize the present invention, the following setting method is specially adopted: 10 parts of Astragalus membranaceus, 12 parts of Coix seed, 9 parts of Codonopsis pilosula, 11 parts of Poria cocos, blood surplus 10 parts of charcoal, 9 parts of red stone fat, 8 parts of white peony root, 6 parts of Baizhu charcoal, 7 parts of tangerine peel charcoal, 6 parts of Bupleurum, 6 parts of Magnolia officinalis, 6 parts of Coptis chinensis, 12 parts of gallinaceous gold, and 11 parts of licorice.

Embodiment 3

[0027] A preparation method for a synthetic drug for the treatment of gastroenteritis, characterized in that: comprising the following steps:

[0028] 1) Reflux extraction of astragalus, coix seed, poria cocos, bupleuri, magnolia officinalis, coptis, and licorice with alcohol extraction to obtain alcohol extraction reflux liquid;

[0029] 2) Dangshen 4-9 times the amount of water, soaked for 1-3 hours, distilled and extracted for 2-5 hours, collected Codonopsis pilosula extract, added appropriate amount of β-cyclodextrin to make clathrate, distilled medicine dregs and residual liquid storage in another device;

[0030] 3) Combine the medicinal residues after extraction of Radix Paeoniae Alba, Gallinarum, and Codonopsis pilosula, the residual liquid, and the medicinal residues after reflux extraction by alcohol extraction, add 4 to 12 times of water and decoct 1 to 3 times, each time for 1 to 3 hours, and decoct together cooking liquid;

[0031] 4) After step 3), add ethanol ...

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PUM

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Abstract

The invention discloses a synthetic drug for treating gastroenteritis and a preparation method thereof. The synthetic drug is prepared from the following raw materials in parts by weight: 8 to 12 parts of astragalus, 10 to 14 parts of semen coicis, 8 to 12 parts of codonopsis pilosula, 9 to 15 parts of poria cocos, 7 to 12 parts of carbonized hair, 9 to 11 parts of red halloysite, 6 to 15 parts of white paeony root, 4 to 8 parts of rhizome atractylodis macrocephalae, 4 to 8 parts of radix prismatomeris connatae, 5 to 7 parts of radix bupleuri, 5 to 7 parts of mangnolia officinalis, 4 to 8 parts of coptis chinensis, 8 to 20 parts of endothelium corneum gigeriae galli and 10 to 15 parts of liquorice. The preparation method comprises the following steps: performing reflux extraction on astragalus, semen coicis, poria cocos, radix bupleuri, mangnolia officinalis, coptis chinensis and liquorice in an alcohol extraction manner, thereby obtaining alcohol extraction reflux. The prepared synthetic drug has small toxic and side effects in clinical application and does not cause damage of gastrointestinal mucosa; moreover, the designed preparation method can be used for efficiently and rapidly preparing the synthetic drug.

Description

technical field [0001] The invention relates to the technical field of biopharmaceuticals, in particular to a synthetic medicine for treating gastroenteritis and a preparation method thereof. Background technique [0002] Gastroenteritis is usually caused by microbial infection, but it can also be caused by chemical poisons or drugs. Typical clinical manifestations are diarrhea, nausea, vomiting and abdominal pain. In healthy adults, gastroenteritis usually causes only discomfort and inconvenience without serious consequences, but can lead to life-threatening dehydration and electrolytes in very ill, debilitated, young or elderly patients disorder. [0003] Infectious gastroenteritis can be caused by infection with viruses, bacteria, and parasites. Poisons and drugs can cause chemical gastroenteritis. Viral infection is the most common cause of gastroenteritis, a variety of viruses can cause gastroenteritis, the most common is rotavirus, followed by Norwalk virus, astrov...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61P1/04A61P1/00A61K33/26A61K35/36A61K35/57
CPCA61K33/26A61K35/36A61K35/57A61K36/076A61K36/233A61K36/284A61K36/344A61K36/481A61K36/484A61K36/575A61K36/65A61K36/71A61K36/718A61K36/752A61K36/8994A61K2236/33A61K2236/331A61K2236/39A61K2236/53A61K2300/00
Inventor 付建军
Owner 成都威迪视特生物科技有限公司
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