Gleptoferron nano-emulsion and preparation method thereof
A technology of iron glucoheptose and nanoemulsion, which is applied in the direction of pharmaceutical formula, emulsion delivery, and medical preparations of non-active ingredients, etc., and can solve strong irritation, piglet stress and other complications, and iron injection pain etc. to achieve the effects of reducing irritation, improving bioavailability and facilitating operation
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Embodiment 1
[0031] An iron glucoheptose nanoemulsion, prepared from the following components by weight: 10 parts of iron glucoheptose, 13.4 parts of Tween80, 6.6 parts of Span80, 15 parts of glycerin, 15 parts of soybean oil, 10 parts of water for injection share.
[0032] The preparation method of the above-mentioned iron glucoheptose nanoemulsion injection comprises the following steps:
[0033] (1) Take the iron glucoheptose anhydrous, surfactant, co-surfactant, oil and water for injection of the prescription amount respectively, and set aside;
[0034] (2) Add the iron glucoheptose anhydrous of the prescribed amount to the water for injection, stir evenly, and use it as the water phase for subsequent use;
[0035] (3) In a 40°C water bath, add the prescribed amount of surfactant and co-surfactant into the oil and mix evenly, and use it as the oil phase for later use;
[0036] (4) In a water bath at 40°C, the water phase containing iron glucoheptose obtained in step (2) was continuou...
Embodiment 2
[0038] An iron glucoheptose nanoemulsion, prepared from the following components by weight: 30 parts of iron glucoheptose, 40 parts of Tween80, 20 parts of Span80, 15 parts of glycerin, 45 parts of soybean oil, 30 parts of water for injection share.
[0039] The preparation method of the above-mentioned iron glucoheptose nanoemulsion injection comprises the following steps:
[0040] (1) Take the iron glucoheptose anhydrous, surfactant, co-surfactant, oil and water for injection of the prescription amount respectively, and set aside;
[0041] (2) Add the iron glucoheptose anhydrous of the prescribed amount to the water for injection, stir evenly, and use it as the water phase for subsequent use;
[0042] (3) In a 40°C water bath, add the prescribed amount of surfactant and co-surfactant into the oil and mix evenly, and use it as the oil phase for later use;
[0043] (4) In a water bath at 40°C, the water phase containing iron glucoheptose obtained in step (2) was continuously...
Embodiment 3
[0045] An iron glucoheptose nanoemulsion, prepared from the following components by weight: 15 parts of iron glucoheptose, 20 parts of Tween80, 10 parts of Span80, 7.5 parts of glycerin, 22.5 parts of soybean oil, 15 parts of water for injection share.
[0046] The preparation method of the above-mentioned iron glucoheptose nanoemulsion injection comprises the following steps:
[0047] (1) Take the iron glucoheptose anhydrous, surfactant, co-surfactant, oil and water for injection of the prescription amount respectively, and set aside;
[0048] (2) Add the iron glucoheptose anhydrous of the prescribed amount to the water for injection, stir evenly, and use it as the water phase for subsequent use;
[0049] (3) In a 40°C water bath, add the prescribed amount of surfactant and co-surfactant into the oil and mix evenly, and use it as the oil phase for later use;
[0050] (4) In a water bath at 40°C, the water phase containing iron glucoheptose obtained in step (2) was continuou...
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