Unlock instant, AI-driven research and patent intelligence for your innovation.

Application of fukien tea extract in preparation of medicine for treating hyperlipidemia

A tea extract, a technology for hyperlipidemia, applied in the application field of Fujian tea extract in the preparation of a drug for treating hyperlipidemia

Active Publication Date: 2020-02-07
HAINAN MEDICAL UNIV
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the study of the extracted and separated components of Fujian tea (Hainan), the inventors found that the Fujian tea extract has a significant lipid-lowering effect, and the effect of the Fujian tea extract on lipid metabolism has not been reported before.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of fukien tea extract in preparation of medicine for treating hyperlipidemia
  • Application of fukien tea extract in preparation of medicine for treating hyperlipidemia
  • Application of fukien tea extract in preparation of medicine for treating hyperlipidemia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Preparation of Fujian tea extract of the present invention: take 200 g of dried Fujian tea leaves, boil and extract with 5-10 times the volume of water, extract twice for 30 minutes each time, filter, combine the two filtrates, and concentrate by rotary steaming at 40 ° C to flow Extract, dilute to 660mL with 0.5% CMC-Na solution.

Embodiment 2

[0027] 1. Preparation of high-fat model

[0028] C57BL male mice weighing 18-22 g were selected. After adapting to the experimental environment for 5 days, 8 mice were randomly divided into the normal group and fed with normal diet; the remaining mice were intraperitoneally injected with TritonWR-1339 to create an animal model of hyperlipidemia. After 7 days of modeling, each model mouse was weighed and randomly divided into 4 groups, 8 mice in each group, which were model control group, atorvastatin positive control group (5mg / kg / d), Fujian tea extract high Dose group (0.2 g / kg / d), Fujian tea extract low-dose group (0.1 g / kg / d). The normal group separated before modeling was divided into 5 groups.

[0029] 2. Preparation of Serum Samples and Liver Tissue Samples

[0030] The normal control group and the model control group were given the same dose of solvent (0.5% CMC-Na) for 7 consecutive days. One hour after the last dose, blood was collected from the heart, and the plasm...

Embodiment 3

[0043]Tablets: Add appropriate amount of starch to Fujian tea extract, press into tablets, each tablet contains 0.1g of Fujian tea extract, and the base tablet weighs 0.5g.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses an application of a carmona microphylla (Lam.) Don extract to preparation of drugs for treating hyperlipidemia. The carmona microphylla (Lam.) Don extract is an aqueous solution extract.

Description

technical field [0001] The invention belongs to the field of medicine, and relates to the properties and uses of Fujian tea and its extract, in particular to the application of the Fujian tea extract in the preparation of medicines for treating hyperlipidemia. Background technique [0002] Metabolic syndrome mainly includes risk factors such as obesity, impaired glucose tolerance, dyslipidemia, and hypertension. With the development of the economy, the improvement of people's living standards and the change of lifestyle, hyperlipidemia has become one of the largest chronic diseases in the world. Hyperlipidemia is high levels of total cholesterol and / or triglycerides in the blood, along with high LDL cholesterol or low HDL cholesterol (which clears cholesterol from the body). The currently reported traditional Chinese medicines for the treatment of hyperlipidemia are: Chuanqiong, Polygonum cuspidatum, Hawthorn, Polygonum multiflorum, Red yeast rice, Chinese kiwi fruit, red p...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/30A61P3/06
Inventor 刘启兵曾渝虞道锐李佩琼曾祥周刘嫱覃娴靖
Owner HAINAN MEDICAL UNIV