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AIDS (acquired immune deficiency syndrome) treatment reactor

A reactor, CD4 technology, applied in the field of biomedicine, to achieve the effect of large side effects and high cost

Active Publication Date: 2017-01-04
ATTACHED OBSTETRICS & GYNECOLOGY OSPITAL MEDICALCOLLEGE ZHEJIANG UNIV +1
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no report on the preparation of CD4+ T cells for the treatment of AIDS in vitro

Method used

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  • AIDS (acquired immune deficiency syndrome) treatment reactor
  • AIDS (acquired immune deficiency syndrome) treatment reactor
  • AIDS (acquired immune deficiency syndrome) treatment reactor

Examples

Experimental program
Comparison scheme
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Embodiment Construction

[0010] figure 1 It is an application schematic diagram of the AIDS treatment reactor proposed according to the present invention.

[0011] figure 2 It is a schematic diagram of the internal structure of the plasma separator proposed according to the present invention.

[0012] image 3 It is a schematic diagram of the internal structure of the AIDS treatment reactor proposed according to the present invention.

[0013] figure 1 Among them, one end of the arterial blood line tube (1) is connected with the arterial blood vessel, and the other end is connected with the plasma separator (4) through the heparin pump (2) and the blood pump (3), and the plasma separator (4) is connected through the plasma pump (6) ) and circulation pipeline (7) are connected with two parallel reactors (8), reactor (9), and then connected with circulation pipeline (10), vein pipeline (5) successively, vein pipeline (5) The other end is connected to the vein.

[0014] figure 2 Among them, 1 is...

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Abstract

The invention relates to an AIDS (acquired immune deficiency syndrome) treatment reactor and belongs to the field of biomedicine. The AIDS treatment reactor is characterized in that an immortalized cell line is prepared by changing the gene structure of a T cell through exogenous gene integration; a CD4+ cell, which can combine HIV (human immunodeficiency virus) and generate a cell factor, is prepared by taking a T cell surface antibody as a cell growth activator through artificial industry; a reactor, which can not only prevent a cell and debris thereof, even HIV, from being filtered out, but also provide a place for the CD4+ cell to generate the cell factor and combine the HIV, is prepared by being wrapped by a high-biocompatibility material; when plasma separated in vitro flows through the reactor, the HIV is combined with the CD4+ cell or enters the cell to be eliminated, and the generated cell factor flows out through cell space along with the plasma to return in vivo, so that an artificial CD4+T cell substitution therapy capable of eliminating HIV and supplementing the cell factor to lead the HIV in vitro to be eliminated is implemented, and is more practicable and has no toxic and side effects compared with the traditional therapy which is limited to kill the HIV in vivo and is difficult to implement.

Description

technical field [0001] The invention relates to an AIDS treatment reactor in the field of biomedicine, which is mainly used for removing HIV dissociated outside the blood cells of AIDS patients in vitro, and at the same time replenishing CD4+T cell factors lacking in the body of AIDS patients to achieve the purpose of treating AIDS. Background technique [0002] AIDS is an infectious disease caused by human immunodeficiency virus (Human Immunodeficiency Virus, HIV). So far, 208 countries and regions in the world have been seriously threatened by AIDS. About 40 million people have been infected with AIDS, and the death toll has exceeded 20 million. About 6,000 people become AIDS-infected people every day, and more than 300 people die every day. on AIDS. HIV-infected people in China are in a period of rapid growth, and the number has far exceeded 1 million at present. AIDS has become another major infectious disease facing mankind after tumors, cardiovascular and cerebrovasc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M1/36
CPCA61M1/3692A61M1/3616
Inventor 翁炳焕李兰娟虞晓鹏杨艳梅黄颖之
Owner ATTACHED OBSTETRICS & GYNECOLOGY OSPITAL MEDICALCOLLEGE ZHEJIANG UNIV
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