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Method for diagnosing lung diseases

An object and spectral technology, applied in the direction of diagnosis, disease diagnosis, diagnostic recording/measurement, etc., can solve unapplied problems

Inactive Publication Date: 2017-02-15
PULMONIR LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Although FTIR has demonstrated applicability in other programs, FTIR analysis has not been applied in the clinical need to manage COPD, where spectral properties of human sputum are obtained to identify differences between COPD individuals and healthy individuals

Method used

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  • Method for diagnosing lung diseases

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Embodiment Construction

[0043] In this specification, the embodiments are described in such a manner that the description to be written can be clear and concise, but it is intended and will be understood that the embodiments may be variously combined or separated without departing from the invention. In this specification, the terms "comprises" and "comprising" are interpreted to mean "comprising among others". These terms are not intended to be interpreted as "consisting only of." Furthermore, in this specification, the term "about" means plus or minus 20%, more preferably plus or minus 10%, even more preferably plus or minus 5%, most preferably plus or minus 2%. For example, it will be appreciated that there may be slight variations, eg, ±5 cm, in the location of specific wavenumber absorbance between FTIR or VFIR techniques due in part to different resolutions. -1 .

[0044] The term "subject" as used herein refers to animals, preferably mammals, and especially humans. In specific embodiments, ...

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Abstract

A method and kit for diagnosing and monitoring the progress of COPD using FTIR spectral analysis of a sputum samples where spectral data is obtained and used to monitor the progression of the disease over time.

Description

[0001] field of invention [0002] The present application relates to methods for diagnosing lung diseases, and in particular chronic obstructive pulmonary disease (COPD). The invention specifically relates to methods for detecting the progression of COPD and the risk of flair ups in an individual. [0003] Background of the invention [0004] COPD is a common progressive disabling disease and a major health burden worldwide. The disease is a disabling and complex disease and is a major public health problem worldwide as it affects an estimated 600 million people and is included in the top 5 leading causes of death. The disease is characterized by partially reversible airflow obstruction driven by in situ inflammatory changes and airway wall remodeling. Consequently, COPD patients have a poor quality of life, exacerbated by flare-ups. These infectious / inflammatory exacerbations increase with disease severity and occur in the context of a variable but progressive natural decl...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/3577A61B5/00G01N33/50
CPCG01N21/35G01N2800/122G01N33/48G01N21/3577G01N33/6893G01N2021/3595G01N2333/4725G01N2400/40
Inventor 保罗·里维斯
Owner PULMONIR LTD