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Compound double-blossom effervescent tablet, preparing method and quality control method

A quality control method and technology for effervescent tablets, which can be used in pharmaceutical formulations, measuring devices, medical preparations with non-active ingredients, etc., and can solve problems such as poor taste, affecting the absorption of active ingredients of drugs, and poor taste.

Inactive Publication Date: 2017-02-22
SHAANXI KANGHUI PHARMA CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The type of preparation in the related art has the problem of bad taste during use. At the same time, when the patient takes tablets and granules, the amount of water ingested by the patient is up to the patient to drink, and the dissolution of the tablets and granules is not sufficient. Therefore, The active substances contained in tablets and granules cannot be dissolved to the maximum extent, which affects the absorption of the active ingredients of the drug by the human body; while liquid preparations such as oral liquids and syrups generally have a poor taste

Method used

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  • Compound double-blossom effervescent tablet, preparing method and quality control method
  • Compound double-blossom effervescent tablet, preparing method and quality control method

Examples

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Effect test

Embodiment 1

[0041] A compound Shuanghua effervescent tablet, said compound Shuanghua effervescent tablet is made up of following raw materials: honeysuckle, forsythia, Andrographis paniculata and Radix Radix are prepared in proportion to the compound Shuanghua extract powder of 500 parts by weight; made of tartaric acid, citrate Citric acid and sodium bicarbonate ratio are the effervescent agent that the ratio of 3.5:2:4.5 makes 180 weight parts; The sodium carboxymethyl starch of 100 weight parts, the lactose of 10 weight parts, by polyethylene glycol and stearic acid 25 parts by weight of lubricant prepared at a ratio of 10:1.

Embodiment 2

[0043] A kind of compound Shuanghua effervescent tablet, described compound Shuanghua effervescent tablet is made up of following raw materials: honeysuckle, forsythia, Andrographis paniculata and Radix Radix Radix are prepared in proportion to the compound Shuanghua extract powder of 900 weight parts; The ratio of citric acid and potassium bicarbonate is that the ratio of 3:2.5:4.5 makes the effervescent agent of 350 weight parts; The dextrin of 230 weight parts, the sucralose of 15 weight parts, by sodium lauryl sulfate and magnesium stearate 30 parts by weight of lubricant were prepared at a ratio of 10:1.

Embodiment 3

[0045] A kind of compound Shuanghua effervescent tablet, described compound Shuanghua effervescent tablet is made up of following raw materials: honeysuckle, forsythia, Andrographis paniculata and Radix Radix Radix Radix Radix Lonicerae make 1000 parts by weight of compound Shuanghua extract powder in proportion; Citric acid and potassium bicarbonate ratio make the effervescent agent of 600 parts by weight in the ratio of 3.5:2:4.5; The sodium starch glycolate of 280 parts by weight, the lactose of 18 parts by weight, by polyethylene glycol and stearic acid 58 parts by weight of lubricant were prepared at a ratio of 10:1.

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Abstract

The invention provides a compound double-blossom effervescent tablet, a preparing method and a quality control method. The compound double-blossom effervescent tablet is prepared from 500-1,000 parts of compound double-blossom extract powder, 180-600 parts of an effervescent, 100-280 parts of a drying agent, 10-18 parts of a corrigent and 25-58 parts of a lubricating agent. After the compound double-blossom effervescent tablet meets water, acid sources and alkali sources in the effervescent tablet are subjected to a chemical reaction to generate carbon dioxide gas to allow the effervescent tablet to be effervesced and disintegrated, the effective constituents in the compound double-blossom effervescent tablet are dissolved and released, the compound double-blossom effervescent tablet is not prone to damage or transformation in the common transportation and storage process, the content of main medicine is not prone to reduction in the long time, and the medicine is not prone to metamorphism; the compound double-blossom effervescent tablet is a dry solid-agent type, and is small in volume, stable in quality and convenient to transport and carry. The invention also provides the preparing method and the quality control method of the compound double-blossom effervescent tablet.

Description

technical field [0001] The disclosure relates to the technical field of traditional Chinese medicine, in particular to a compound Shuanghua effervescent tablet, a preparation method and a quality control method. Background technique [0002] Honeysuckle is also known as two flowers, double flowers, golden flowers, silver flowers and honeysuckle flowers. "Shen Nong's Materia Medica" contains: "Honeysuckle is cold in nature and sweet in taste. It has the effects of clearing away heat and detoxifying, cooling blood and removing stasis. Acne, sores, furunculosis, redness, swelling, heat pain, feces, pus and blood" and so on. "Compendium of Materia Medica" discusses in detail that honeysuckle has the effect of "long-term service, light body, prolong life". In the 1980s, the National Ministry of Health carried out chemical analysis on honeysuckle successively. The results showed that: Honeysuckle contains a variety of trace elements and chemical components necessary for the human...

Claims

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Application Information

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IPC IPC(8): A61K36/634A61K9/46A61K47/02A61K47/12G01N30/02G01N30/90A61P29/00A61P39/02A61P11/04A61P11/00A61P37/04
CPCA61K36/19A61K9/0007A61K9/2009A61K9/2013A61K36/315A61K36/35A61K36/634G01N30/02G01N30/90A61K2300/00
Inventor 王延岭
Owner SHAANXI KANGHUI PHARMA CO LTD
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