Oral ulcer mucoadhesive film and preparation method thereof

Abstract

The invention provides an oral ulcer mucoadhesive film and a preparation method thereof. The oral ulcer mucoadhesive film is prepared by honeysuckle flower, menthol, vitamin B [2], borneol, tetracaine hydrochloride, sorbic acid, prednisone acetate, chlortetracycline hydrochloride, glycerin, stevioside, ethanol PVA 17-88 and purified water. Compared with the prior art, the film has good flexibility and tensile strength, can rapidly being expended and dissolved when meets water, a high-density protection drug film layer is formed on the oral cavity mucous membrane, and the effect for rapidly relieving swelling and pain with long term can be reached; oral cavity mucous membrane is employed for direction drug administration, the drug can be directly effected on the disease, simultaneous treatment of principal and subordinate symptoms can be reached, curative effect is fully performed; a lattice impression technology is employed on the technology, administration with divided dose is accurate, curative effect is increased, quality is stable, the oral ulcer mucoadhesive film has no toxic and side effect for oral cavity, and is safe and effective; and has the advantages of small volume, light weight, and convenient carrying and usage.

Description

technical field [0001] The invention relates to an oral ulcer patch and a preparation method thereof. Background technique [0002] Oral ulcer is also called recurrent aphtha, is commonly called as aphthous ulcer, is a kind of common oral mucosa disease. Recurrent oral ulcers refer specifically to a class of unexplained, recurrent but self-limited, solitary, round or oval ulcers. It is also called recurrent aphthous ulcer (Aphthous is the meaning of "burning and ulceration" in Greek) or recurrent aphthous ulcer. Clinically, it can be divided into three types according to the size, depth and number of ulcer manifestations: recurrent mild oral ulcer, recurrent stomatitis ulcer and recurrent necrotizing mucosal periadenitis. [0003] Recurrent oral ulcers are one of the most common diseases in oral mucosal diseases. In people's life, there are almost no oral ulcers that do not occur, but some people have occasional attacks, and some people have frequent attacks; moreover, abo...

AI Technical Summary

Problems solved by technology

The film is a kind of polymer material as the matrix, which absorbs one or several drug ingredients and has a long maintenance time.