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Skin-whitening, anti-aging and anti-allergic hesperidin composition, application and preparation

A technology of hesperidin and composition, which is applied in the field of hesperidin composition and its application and preparation, to achieve the effects of low production cost, reducing ear swelling and improving SOD activity

Active Publication Date: 2017-04-19
瑞康东方医学研究(北京)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] At present, there is no report on the combination of hesperidin and sinmarin for the preparation of cosmetic compositions with whitening, anti-oxidation and anti-allergic functions

Method used

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  • Skin-whitening, anti-aging and anti-allergic hesperidin composition, application and preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Embodiment 1, the preparation of ointment

[0033] Get 5 kg of the composition containing hesperidin and sine marin, 10 kg of emulsifier, 8 kg of silicone oil and 4 kg of cetearyl alcohol and dissolve it in 3 kg of olive oil, mix well to obtain an oil phase; get 10 kg of glycerin and dissolve it in an aqueous solution containing calcium sulfate 40kg, mixed evenly to obtain the water phase; the oil phase and the water phase were stirred and mixed evenly at room temperature, then heated to 38°C and melted for 3 minutes, and homogenized for 20 minutes, to obtain, wherein the emulsifier was hydrogenated lecithin and polyethylene glycol Alcohol 4000 is composed at a weight ratio of 1:0.03, wherein, the weight ratio of hesperidin and silymarin in the composition containing hesperidin and sinicine is 1:0.8.

Embodiment 2

[0034] Embodiment 2, the preparation of emulsion

[0035] Get 8 kg of the composition containing hesperidin and sine marin, and dissolve 8 kg of emulsifier in 3 kg of olive oil, and mix to obtain an oil phase; get 22 kg of glycerin and dissolve it in 50 kg of an aqueous solution containing calcium sulfate, and mix to obtain an aqueous phase; Stir and mix the oil phase and the water phase at room temperature, heat up to 38°C and melt for 3 minutes, and homogenize for 20 minutes to obtain it. Composition by weight ratio, wherein, the weight ratio of hesperidin and silymarin in the composition containing hesperidin and sinicine is 1:1.

Embodiment 3

[0036] Embodiment 3, the preparation of membrane agent

[0037] Heat 4kg and 8kg of polysorbate 80 containing hesperidin and sigmarin to dissolve them, add 0.3kg of carbomer, stir well, add 0.3kg of triethanolamine to adjust the pH to 7.0, and add 65kg of deionized water , 10kg of polyvinyl alcohol, heated to dissolve it, to obtain final product, wherein, the weight ratio of hesperidin and sinicin in the composition containing hesperidin and sinicin is 1:0.6.

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Abstract

The invention belongs to the field of cosmetics and particularly relates to a skin-whitening, anti-aging and anti-allergic hesperidin composition, an application and a preparation. According to the composition containing hesperidin and pectolinarin, provided by the invention, the number of melanin particle-containing positive cells and the content of tyrosinase can be remarkably reduced, the SOD activity can be remarkably improved, the MDA content can be reduced, and the ear swelling and the licking frequency of an experimental animal can be remarkably reduced; and the hesperidin and the pectolinarin are compounded to achieve the effects of remarkably whitening skin, resisting aging and resisting allergy.

Description

technical field [0001] The invention belongs to the field of cosmetics, and in particular relates to a whitening, anti-aging and anti-allergic hesperidin composition and its application and preparation. Background technique [0002] In recent years, with the acceleration of people's life and work rhythm and the aggravation of environmental pollution, people are facing more and more skin problems, especially dark complexion and pigmentation have become common problems, and whitening and anti-aging cosmetics are also Therefore, it has become a hot spot in the field of skin care product development. With the increasing maturity of people's consumption concept, consumers pay more attention to this kind of cosmetics not only on their efficacy, but also on their safety. Compared with chemical whitening and anti-oxidants that have safety risks such as irritation, natural whitening and anti-aging agents derived from traditional Chinese medicine have the advantages of safety, mildne...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/60A61K8/86A61K8/55A61K8/92A61K8/23A61Q19/02A61Q19/08A61P37/08
CPCA61K8/23A61K8/553A61K8/602A61K8/86A61K8/922A61K2800/52A61Q19/02A61Q19/08
Inventor 郭姣
Owner 瑞康东方医学研究(北京)有限公司
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