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Lycium ruthenicum polysaccharide chewable tablet

A technology of black wolfberry and chewable tablets, which is applied in the direction of plant raw materials, food ingredients as taste improvers, food forming, etc., can solve the problem of lack of black wolfberry polysaccharides, etc., and achieve rapid drug dissolution, good taste, and high bioavailability Effect

Active Publication Date: 2017-05-17
河北康平健康产业有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, most of the research on black wolfberry polysaccharides focuses on the extraction method / process research, pharmacological activity research, etc., and there is a lack of functional health food involving black wolfberry polysaccharides as a single active ingredient

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A black wolfberry polysaccharide chewable tablet, the main components include: black wolfberry polysaccharide 45g, mannitol 250g, citric acid syrup 8g, hydroxypropyl cellulose 12g, povidone K30 24g, micropowder silica gel 5g; the preparation method includes the following steps :

[0025] (1) Preparation of black wolfberry polysaccharide:

[0026] (a) select high-quality black wolfberry, wash with clean water, dry, and pulverize into coarse powder for subsequent use;

[0027] (b) the black wolfberry coarse powder obtained in step (a) is extracted 3 times with hot water, 2h each time, and the obtained extract is combined, filtered, and concentrated to one-half of the original volume;

[0028] (c) adding 2 times the volume of petroleum ether extraction to the concentrated solution obtained in step (b), extracting 4 times, discarding the petroleum ether extraction layer, and combining the extracted aqueous layer for subsequent use;

[0029] (d) adding an appropriate amoun...

Embodiment 2

[0036] A black wolfberry polysaccharide chewable tablet, the main components include: black wolfberry polysaccharide 50g, mannitol 270g, citric acid syrup 8g, hydroxypropyl cellulose 10g, povidone K30 25g, micropowder silica gel 6g; the preparation method includes the following steps :

[0037] (1) Preparation of black wolfberry polysaccharide:

[0038] (a) select high-quality black wolfberry, wash with clean water, dry, and pulverize into coarse powder for subsequent use;

[0039] (b) the black wolfberry coarse powder obtained in step (a) is extracted twice with hot water, 2.5h each time, and the obtained extract is combined, filtered, and concentrated to one-half of the original volume;

[0040] (c) adding 1.5 times the volume of petroleum ether extraction to the concentrated solution obtained in step (b), extracting 3 times, discarding the petroleum ether extraction layer, and combining the extracted aqueous layer for subsequent use;

[0041] (d) adding an appropriate amo...

Embodiment 3

[0048] A black wolfberry polysaccharide chewable tablet, the main components include: black wolfberry polysaccharide 60g, mannitol 300g, citric acid syrup 9g, hydroxypropyl cellulose 15g, povidone K30g 30g, micropowder silica gel 6g. The preparation method includes the following steps:

[0049] (1) Preparation of black wolfberry polysaccharide:

[0050] (a) select high-quality black wolfberry, wash with clean water, dry, and pulverize into coarse powder for subsequent use;

[0051] (b) the black wolfberry coarse powder obtained in step (a) is extracted 3 times with hot water, each time for 2.5h, and the obtained extract is combined, filtered, and concentrated to one-half of the original volume;

[0052] (c) adding 2 times the volume of petroleum ether extraction to the concentrated solution obtained in step (b), extracting 3 times, discarding the petroleum ether extraction layer, and combining the extracted aqueous layer for subsequent use;

[0053] (d) adding an appropriate am...

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Abstract

The invention relates to a Lycium ruthenicum polysaccharide chewable tablet which mainly comprises Lycium ruthenicum polysaccharides, mannitol citric acid syrup, hydroxypropyl cellulose, povidone K30 and micropowder silica gel. The Lycium ruthenicum is leached with hot water and extracted with petroleum ether to remove grease and pigments, thereby greatly removing the impurities and maintaining more polysaccharide components; and after alcohol precipitation, gel column chromatography is carried out to perform purification and refinement, so the drug effect is centralized, thereby fully displaying the pharmacological activity of the Lycium ruthenicum polysaccharides. The chewable tablet has the advantages of favorable mouthfeel, short disintegration time, favorable dispersion effect, quick drug leaching, quick absorption, high bioavailability and the like. The chewable tablet is convenient to take, and is especially suitable for children, old people and patients with dysphagia to take.

Description

technical field [0001] The invention relates to a black wolfberry polysaccharide chewable tablet, which belongs to the field of functional food. Background technique [0002] Black wolfberry, also known as black fruit wolfberry, belongs to the genus of Solanaceae. Perennial shrub with thorns, spherical berries, purple-black when mature, with high photosynthetic efficiency and strong resistance to stress, is a unique wild plant in northwest desert area in my country, which is distributed in Shanxi, Ningxia and Gansu. , Qinghai, Xinjiang, Tibet and other regions. Black wolfberry is sweet and juicy, rich in vitamins, organic acids and sugars, and is often eaten raw or juiced as beverages. Black wolfberry has certain medical and health care functions. It is used in Tibetan medicine to treat heart fever, heart disease, irregular menstruation, and menopause. [0003] Black wolfberry is rich in protein, fat, carbohydrates, free amino acids, organic acids, minerals, trace elements...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K31/715A61P39/00A61P3/10A23L33/105A23L33/125A23P10/28C08B37/00
CPCA23V2002/00A61K9/0056A61K9/2054A61K31/715A61K36/815A61K2236/331A61K2236/35A61K2236/39A61K2236/55C08B37/0003C08B37/006A23V2200/14A23V2200/30A23V2250/21
Inventor 贾东升谢晓亮温春秀刘灵娣崔施展李荣乔田伟边建波
Owner 河北康平健康产业有限责任公司
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