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Pharmaceutical composition for treating recurrent oral ulceration

A technique for oral ulcers and compositions, which is applied in the field of pharmaceutical compositions for treating recurrent oral ulcers and its preparation, and can solve problems such as unsatisfactory curative effect and unclear etiology of recurrent oral ulcers

Inactive Publication Date: 2017-05-17
JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The etiology of recurrent oral ulceration is not yet clear, so although there are many treatment methods, the curative effect is not satisfactory.

Method used

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  • Pharmaceutical composition for treating recurrent oral ulceration

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1: the pharmaceutical composition for the treatment of recurrent oral ulcer and preparation method thereof

[0035] The composition and weight parts of the raw materials of the pharmaceutical composition for treating recurrent oral ulcers are: Grasshopper 925g, Kamba japonica 586g, Trilobite bean pterostaloside 16g, Wild fire rope 165g, and Diandaozicai 68g;

[0036] Preparation:

[0037] (1) According to the ratio of raw materials, take grasshopper, kalebasin, pteroside, wild fire rope, and dandaozicai, mix them evenly, use ethanol with a concentration of 39.5% by weight as a solvent, and extract by warm soaking at 39.5°C. 9 times, each extraction time is 0.8 hours, each solvent consumption is 13 times of the total weight of the crude drug, filtered to obtain medicinal residue A and extract A, the extract A reclaims ethanol, concentrates to a relative density of 1.08, and filters After that, the medicinal solution passes through the CD180 macroporous adsorp...

Embodiment 2

[0040] Embodiment 2: the pharmaceutical composition for the treatment of recurrent oral ulcer and preparation method thereof

[0041] The composition and parts by weight of the raw materials of the pharmaceutical composition for treating recurrent oral ulcers are: Grasshopper 922g, Kamba japonica 590g, Trilobite bean pteroside 15g, Wild fire rope 168g, and Diandaozicai 65g;

[0042] Preparation:

[0043] (1) According to the ratio of raw materials, take grasshopper, kalebasin, pteroside, wild fire rope, and dandaozicai, mix them evenly, use ethanol with a concentration of 39.5% by weight as a solvent, and extract by warm soaking at 39.5°C. 9 times, each extraction time is 0.8 hours, each solvent consumption is 13 times of the total weight of the crude drug, filtered to obtain medicinal residue A and extract A, the extract A reclaims ethanol, concentrates to a relative density of 1.08, and filters After that, the medicinal solution passes through the CD180 macroporous adsorpti...

Embodiment 3

[0046] Embodiment 3: the pharmaceutical composition for the treatment of recurrent oral ulcer and preparation method thereof

[0047] The composition and parts by weight of the raw materials of the pharmaceutical composition for treating recurrent oral ulcers are: Grasshopper 928g, Kamba Cinnamomum 582g, Trilobite bean pteroside 17g, Wild fire rope 162g, and Diandaozicai 70g;

[0048] Preparation:

[0049] (1) According to the ratio of raw materials, take grasshopper, kalebasin, pteroside, wild fire rope, and dandaozicai, mix them evenly, use ethanol with a concentration of 39.5% by weight as a solvent, and extract by warm soaking at 39.5°C. 9 times, each extraction time is 0.8 hours, each solvent consumption is 13 times of the total weight of the crude drug, filtered to obtain medicinal residue A and extract A, the extract A reclaims ethanol, concentrates to a relative density of 1.08, and filters After that, the medicinal solution passes through the CD180 macroporous adsorp...

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Abstract

The invention discloses a pharmaceutical composition for treating recurrent oral ulceration and a preparation method thereof. The pharmaceutical composition is prepared from grasshopper, phyllagathis cavaleriei, trifolirhizin, grewia eriocarpa and mazus stachydifolius as medicinal raw materials by proportioning, can be prepared into various dosage forms according to conventional preparation processes, and has an obvious curative effect when used for treating recurrent oral ulceration.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a pharmaceutical composition for treating recurrent oral ulcer and a preparation method thereof. Background technique [0002] The etiology of recurrent oral ulceration is not yet clear, so although there are many treatment methods, the curative effect is not satisfactory. Clinically, local treatment combined with systemic treatment can prolong the intermittent period, shorten the attack period, and alleviate the condition. The main principles of local treatment of recurrent oral ulcers are anti-inflammatory, pain relief, and promotion of healing. Promoting healing is the main principle. According to the clinical manifestations of various diseases and syndromes of recurrent oral ulcers, traditional Chinese medicine dialectically and classifies the causes of the disease according to the combination of yin and yang, exterior and interior, cold and h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/80A61P1/02A61K35/64A61K31/7048
CPCA61K31/7048A61K35/63A61K36/185A61K36/80A61K2236/333A61K2236/55A61K2236/39A61K2236/51A61K2300/00
Inventor 不公告发明人
Owner JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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