293 results about "Oral ulcerations" patented technology

New oral rinse solutions and mouthwashes are provided. The oral rinse solutions comprise essential oil and alcohol, supplemented with hydrogen peroxide, and natural extracts. The essential oil and/or alcohol can be provided as part of a base composition. The most preferred base compositions are antiseptic mouthwashes containing the essential oil and/or alcohol. Alternatively, the ingredients can be individually added to the inventive composition. The oral rinse solutions provide antimicrobial activity while soothing oral inflammations and irritations, thus being useful for treating, alleviating, and promoting healing of a wide variety of oral ailments such as periodontal disease (gingivitis and periodontitis), plaque, oral inflammation, toothaches, oral ulcerations, dry socket, dentin hypersensitivity, and halitosis, as well as address aesthetic issues such as bad breath and tooth discoloration.

The invention discloses a sustained-release sticking film for treating oral ulcer and relates to the technical field of medical equipment and preparation technology thereof. The sustained-release sticking film is of a circular sheet and provided with a three-layer structure, wherein the upper layer is a sustained-release coating (1) which contacts with an oral ulcer surface, the lower layer is a polyacrylic acid film (3) with a protective effect, a medicament-loaded layer of the middle layer takes bacterial cellulose as a medicament carrier, and a medicament loading substance with a sustained-release effect enters a bacterial cellulose membrane by using a dipping method to obtain a bacterial cellulose/medicament loading substance composite film (2). The sustained-release sticking film disclosed by the invention is good in adhesion, permeability and biocompatibility, large in medicament loading capacity, long in local effect time, capable of relieving pain, promoting wound healing and preventing wound infection. The sustained-release sticking film is suitable for oral traumas of oral ulcers, oral mucosal bites and the like.

The invention provides a lamioplomis rotata medical toothpaste which is prepared with lamioplomis rotate extract as main medical active material and commonly used auxiliary material through common technique. The medical toothpaste of the invention has the functions of easing pain, stopping bleeding, diminishing inflammation and preventing bacteria and can effectively cure oral diseases such as ngival hemorrhage, ngivitis, periodontitis, gingival atrophy and oral ulcer; meanwhile, the invention can clean the teeth and the mouth, nurse the mouth and keep the foul breath fresh.

The invention relates to an oral spray for inflammatory diseases of the oral cavity and a preparation method thereof. The oral spray comprises the following components: 0.1-5% of water-soluble chitosan, 0.5-5% of propolis extract, 0.1-1% of lactoferrin, 0.01-0.5% of lactoperoxidase, 0.1-0.5% of lysozyme, 0.01-0.1% of immunoglobulin, 1-10% of bovine colostrum extract, 1-10% of anti-caries sweetener, 0.8-1.2% of cold aromatic, 0.1-1% of preservative and the balance of water for injections. The preparation method is characterized by mixing the components, stirring uniformly, filling into an oral sprayer, and sterilizing at 85 DEG C for 15 minutes to obtain the finished product. The oral spray has the effect of immediately and rapidly treating inflammatory diseases of the oral cavity and the functions of resisting bacteria and viruses, relieving pains, reducing gum inflammation and blooding, promoting the healing of oral ulcer wounds, treating acute and chronic pharyngitis, moistening and freshening the oral cavity and removing halitosis. The oral spray has the advantages of simple and convenient large-scale production process and no environmental pollution in the production process.

The invention relates to a purely Chinese traditional medical film for curing oral ulcer, which is characterized in that according to weight percentage, the purely Chinese traditional medical film consists of 0.03-0.05g of allicin, 2-4g of catechu, 1-2g of borneol, 0.5-1.5g of borax, 0.5-1.5g of corn mint, 1-3g of gum tragacanth, 30-40ml of sodium alginate, 4-5ml of sodium carboxymethylcellulose, ethanol and 100ml of distilled water. The purely Chinese traditional medical film is completely purely Chinese traditional medical formula, is the best formulation for curing ulcer of oral mucosa, avoids side effects caused by using antibiotics and glucocorticoid, and has the advantages of obvious curative effect, convenient use, small side effect and curing cause and symptom.

The invention discloses a traditional Chinese medicine composition for preventing oral inflammation and an oral care product containing the same. The traditional Chinese medicine composition is a mixture of three or four of lophatherum gracile, platycodon grandiflorum, liquorice and mint; the traditional Chinese medicine composition is obtained by extracting medicinal plants, wherein the additive amount of the lophatherum gracile extract, platycodon grandiflorum extract and liquorice extract is respectively 0.01-10.0%, and the additive amount of the mint is 0.1-8.0%; and the traditional Chinese medicine composition is applied to the oral care product. The traditional Chinese medicine composition is suitable for people suffering from inflammation and toothache, red eye and swollen throat and sore of lips and tongue. Through a combination technology, the traditional Chinese medicine composition has the functions of clearing heat, decreasing internal heat, and relieving swelling and pain. By applying the traditional Chinese medicine composition to the oral care product, the product has the functions of alleviating redness and swelling of the gum, bleeding, oral ulcer, gingivitis, swelling and pain in throat and the like. The oral care product is natural and safe, is remarkable in curative effect, and is suitable for being used during oral discomfort as well as daily oral care.

The invention relates to a Chinese medicinal preparation for treating dental ulcer. The Chinese medicinal preparation is prepared by decocting the following bulk pharmaceuticals with the conventional traditional Chinese medicine decoction method in parts by weight: 10-30 parts of fructus gardeniae, 10-30 parts of honeysuckle flower, 5-30 parts of pseudo-ginseng root, 10-30 parts of coptis root, 10-20 parts of lightyellow sophora root, 5-20 parts of common lophatherum herb and 2-10 parts of borneol. The preparation has the characteristics of readily available raw materials which are Chinese medicinal herbs, no toxic or side effect, sequela resistance, unique action, easiness for preparing, good effect, quick response, remarkable curative effect, good pain relieving effect, quick healing action on ulcer, delayed relieving course and capability of regulating the immunologic function of a mechanism, can be used for basically healing dental ulcer within one week, can be used for truly achieving the effects of quick response and treatment of both principal and secondary aspects of a disease, and can be used for treating various dental ulcer diseases.

The invention discloses a compound Chinese medicine composition, the compound Chinese medicine composition is prepared from raw materials by weight: 0.8-6 parts of fructus piperis longi, 0.6-4.5 parts of Scutellaria baicalensis, 0.4-3 parts of dandelion, 0.4-3 parts of honeysuckle and 0.4-1.6 parts of mint. The invention also discloses compound Chinese medicine toothpaste containing the compound Chinese medicine composition. The compound Chinese medicine toothpaste has the effects of clearing away heat and toxic materials, relieving fever and pains, preventing bleeding gums, inhibiting bacteria, diminishing inflammation, reducing internal heat, effective preventing gingivitis, periodontitis, gingival bleeding, oral ulcers, sore gums and toothache, strengthening teeth and protecting gums; can well clean and care oral cavity, removes oral cavity odors, keeps fresh breath, and has obvious public health value and commercial value.

The invention relates to a novel broad-spectrum anti-inflammation analgesic drug for curing various oral diseases. The invention discloses a main compound extracted from mangosteen:Garcinia mangostana, i.e. mangostin, the mangostin is taken as the maim active component and combined with the commonly-used filling agents in various pharmaceutical industries to be prepared into various dosage forms or as drugs, health care products, food additives and the like, and the mangostin can be internally and externally used for ulcerative stomatitis, pharyngitis and the like, and also can be used for preening and curing the oral diseases, for example, the benign and malignant tumors of oral cavity. The content of the mangostin is between 1.2 and 99.8 percent, can be separately used or used by matching other substances, and also can be used for preventing and curing the oral diseases of animals. The product overcomes the defects in the prior drug for curing the oral diseases, such as poor effect, irritability, high recurrence rate, side-effect and the like, and is the efficient and broad-spectrum new drug with anti-inflammation, rapid abirritation, non-toxicity, no side-effect and enhanced immunity.

The invention provides a mouthwash. The mouthwash contains gynura divaricata juice, mint oil, clove oil, stevioside, ethanol and water. The mouthwash has good effects of diminishing inflammation and relieving pain, and can be used for preventing or treating oral ulcer, decayed teeth and halitosis.

Provided is a hyaluronic acid (HA) composition for use in treating or preventing mucosa related disorders or diseases including a mixture of HAs having different average molecular weights and different rheological, isolation, tissue scaffold and degradation properties. The resulting formulation demonstrates an optimal balance between adhesion, tissue scaffold and treating time on the treatment and prevention of mucosa related disorders or diseases including conjunctivitis, otitis, allergic rhinitis, gingivitis, oral ulcer, bronchitis, gastroesophageal reflux disease (GERD), esophagitis, gastritis, enteritis, peptic ulcer, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), urethritis, cystitis and vaginitis.

The invention discloses a traditional Chinese medicine composition for treating boil of the lips and the tongue and ulcerations of oral cavity. The composition is prepared from the following material medicines in portion by weight: 100 to 300 portions of baikal skullcap root, 50 to 200 portions of Chinese goldthread, 80 to 150 portions of bark of yellow corktree bark, 80 to 150 portions of rhubarb, 50 to 200 portions of root of pseudo-ginseng, 50 to 150 portions of red peony root, 1 to 10 portions of asarum herb, 1 to 5 portions of artificial cow-bezoar and 1 to 5 portions of borneol. The composition has the advantages that: all components are active components of the traditional Chinese medicine and are wide in source and low in price. The traditional Chinese medicine composition can be prepared into powder, tablets or pellicles, and is convenient to use.

The invention relates to a traditional Chinese medicine composition used for treating oral ulcer. The composition is composed of traditional Chinese medicine raw materials of: 15g of raw rehmannia root, 15g of wheat, 10g of weeping forsythia fruit, 9g of cape jasmine, 30g of common yam rhizome, 15g of honeysuckle flower, 15g of white peony root, 10g of golden thread, 15g of tree peony root-bark, 10g of henon bamboo leaf, 10g of Chinese thorowax root, 12g of Baikal skullcap root, 15g of amur corktree bark, 6g of blackberry lily, 10g of Philippine violet herb, 9g of common andrographis herb, and 12g of tonkin sophora root. During treatment, the traditional Chinese medicine is added into 1500ml of water, and is decocted for 30min by using a mild fire; dregs are removed by filtering, and a decoction is obtained. One decoction is taken one day, and a treatment course comprises 7 days. With the formulation of the traditional Chinese medicine composition, functions such as heat clearing, dampness eliminating, internal fire removing, and detoxifying are provided. With the composition, internal sore swollen poison can be removed, and oral ulcer can be treated. Both the symptoms and the root cause can be treated. The composition also has the advantages of rich medicine sources and low cost.

The present invention relates to a medicine for curing mouth ulcer. The present invention is made from the raw materials according to the following weight portions: 4 to 8 portions of milk veteh, 3 to 6 portions of angelica, 2 to 5 portions of radix bupleuri, 3 to 6 portions of corktree bark, 0.1 to 1 portions of borneol, 3 to 6 portions of honeysuckle, 2 to 6 portions of nantural oindigo, 1 to 4 portions of white alum, 3 to 7 portions of liquorice and 2 to 6 portions of dwarf lilyturf root. The present invention with simple preparation is obtained by totally grinding the materials and filtering through a 100-mesh screen. By adopting the stickiness of Chinese medicine, the present invention is directly attached to the afflicted part, so as to achieve the curing effect. The medicine for curing mouth ulcer provided by the present invention is a common Chinese medicine with simple prescription, low price, clear curing effect and strong patient adaptability, which is suitable for being widely promoted in clinics.

The invention discloses toothpaste containing propolis, notoginseng roots, subshrubby peony root-barks, rhizome of deltoid goldthread and ural licorice roots and a preparation method of the toothpaste, and relates to the field of oral care. The toothpaste is natural care toothpaste containing propolis, notoginseng root, subshrubby peony root-bark, rhizome of deltoid goldthread and ural licorice root extracts, and has remarkable curative effects on gingivitis, gingival bleeding, oral ulcer, halitosis and the like. The propolis has the functions of promoting tissue repair, resisting and inhibiting bacteria, diminishing inflammation, alleviating pain and stopping bleeding. The notoginseng roots have the functions of promoting blood circulation, arresting bleeding, resisting thrombi, enhancingimmunity and effectively improving oral mucosa microcirculation. The subshrubby peony root-barks have the functions of clearing heat, cooling blood, diminishing inflammation, alleviating pain and promoting blood circulation to remove blood stasis. The rhizome of deltoid goldthread has the functions of clearing away the heart-fire, clearing away heat and toxic materials and resisting inflammationand viruses. The ural licorice roots have the functions of clearing away heat and toxic materials and discharging fire. Therefore, the toothpaste containing the propolis, notoginseng root, subshrubbypeony root-bark, rhizome of deltoid goldthread and ural licorice root extracts has more remarkable effects of relieving pain, diminishing inflammation, resisting gingivitis, gingival bleeding and pin,repairing oral mucosa tissues, inhibiting the bacteria and preventing halitosis.

The invention relates to a toothpaste composition for maintenance of an oral cavity. The toothpaste composition is prepared from the following components in parts by weight: 20-29 parts of deionized water, 0.07-0.15 part of sodium azulene sulfonate, 0.2-0.3 part of sodium hexametaphosphate, 0.2-0.3 part of saccharin, 19-25 parts of sorbitol, 0.4-0.7 part of clove oil, 0.03-0.06 part of wintergreenoil, 0.3-0.5 part of menthol, 0.04-0.07 part of eucalyptus oil, 0.04-0.08 part of thymol, 43-46 parts of calcite, 1.8-2.5 parts of silicon dioxide, 1.0-1.3 parts of sodium carboxymethylcellulose, 0.5-1.5 parts of bioactive glass, 0.7-1.0 part of SM gel and 2.0-2.5 parts of sodium dodecyl sulfate. The toothpaste composition provided by the invention can be used for effectively solving the problemsof oral hygiene and tooth protection health care and has the effects of preventing, alleviating and maintaining oral ulcer, dentin hypersensitivity, oral inflammation and decayed tooth.

The invention discloses an adhering film against oral ulcer and a preparation method and application thereof. The adhering film comprises, by mass percentage, 0.1-99.8wt% of bioactive glass, 0.1-99.8wt% of adhesive and 0.1-60wt% of water repellent agent. The bioactive glass in the adhering film against oral ulcer has an antibacterial effect and can relieve pain and promote union of the ulcer surface. The adhesive enables the adhering film against oral ulcer to firmly adhere to the ulcer part, the stimulation to the ulcer surface caused by foreign matter is effectively isolated, and thus the pain is relieved. A hydrophobic layer makes the adhering film against oral ulcer not adhere to the surfaces of other mucous membranes such as the gingiva and only adhere to the ulcer surface, the residence time of the adhering film in the oral cavity is remarkably prolonged, the water absorption speed of an adhesive layer can be slowed down, the adhering film against oral ulcer maintains a long time membrane state at the ulcer part, the adhesion time is increased, and the adhering film further has an effect of promoting union.

The invention discloses a medicine for treating recurrent oral ulceration, which comprises bezoar, root of rehmannia, radix scrophulariae, scutellaria baicalensis, jasmine, folium isatidis, borneol, honeysuckle, fructus forsythiae, cortex dictamni, dandelion, giant knot weed, selfheal, raw mulberry bark, hedyotis diffusa, cacumen biotae, salvia miltiorrhiza, fritillaria, coptis chinensis, tendril-leaved fritillary bulb, rheum officinale, root of common peony, liquorice, myrrh, mastic and pearl. The medicine for treating recurrent oral ulceration which is prepared from the bulk drugs has the advantages of remarkable curative effect and small side effects, and the oral ulceration is difficult to relapse.

The present invention discloses a suspension composition for treating oral mucositis caused by chemoradiotherapy, and relates to a new drug for treating oral mucositis. The suspension composition comprises: 1, local anesthetics; 2, histamine 1 receptor antagonists; 3, a mucosal repairing agent and a drug dispersing agent; 4, an anti-foaming agent; 5, microcrystalline cellulose; 6, unreactive assistant materials; 7, pure water. The preparation method comprises: 1, preparing a solution I; 2, preparing a solution II; 3, adding the solution I to the solution II at a stirring state, completely stirring, adjusting the pH value of the mixed solution to 6-9 to obtain the suspension composition. According to the present invention, the suspension composition provided by the present invention has characteristics of good uniformity and strong stability, is not easy to agglomerate when the suspension composition is placed for a long time; the preparation method has characteristics of simple process and low production cost; the suspension composition can be applicable for treating the oral mucositis caused by the chemoradiotherapy, and severe mouth ulcers caused by anaerobic bacteria; the suspension composition provides effects of analgesia, inflammation eliminating and mucosa repairing; the clinical efficacy of the suspension composition is obvious; the use of the suspension composition is convenient and safe.

A Chinese medicine for treating oral ulcer is prepared from 17 Chinese-medicinal materials including asparagus root, liquorice root, honey, astragalus root, etc.

The invention discloses a traditional Chinese medicinal compound thermosensitive hydrogel for treating oral ulcer. The traditional Chinese medicinal compound thermosensitive hydrogel is prepared from the following raw materials in percentage by weight: 17 to 35 percent of a matrix, 5 to 30 percent of a medicinal material and medicinal material extracting solution and the balance of a solvent, wherein the medicinal material and medicinal material extracting solution is prepared from an indigo naturalis extracting solution, a galla chinensis nut extracting solution and an auxiliary medicinal material; the auxiliary medicinal material is one or a combination of a rhizoma bletillae extracting solution and borneolum syntheticum. According to the traditional Chinese medicinal compound thermosensitive hydrogel, the thermosensitive hydrogel is prepared from four traditional Chinese medicaments, i.e. indigo naturalis, galla chinensis nut, rhizoma bletillae and the borneolum syntheticum, which form a basic formula, and is applied in a solution state, that is, a phase change semisolid preparation is formed at a part subjected to drug administration, so that the effects of prolonging the contact time of the medicament and oral mucosa, reducing the burst release effect, slowly releasing the medicament, enhancing absorption and prolonging the acting time are achieved, healing of the surface of a wound can be accelerated, and recurrent oral ulcer can be effectively treated; a process is mature, and the thermosensitive hydrogel is easy to industrially produce; only water and ethanol are adopted as extraction solvents in a preparation process, so that environmental pollution is avoided.