Mouth wash for oral cancer rehabilitation treatment and preparation method of mouth wash

Abstract

The invention discloses mouth wash for oral cancer rehabilitation treatment and a preparation method of the mouth wash. The mouth wash is prepared from the following raw materials in parts by weight: 90-100 parts of deionized water, 10-14 parts of ethanol, 8-12 parts of an oldenlandia diffusa extract, 8-12 parts of rabdosia rubescens, 8-12 parts of radix curcumae, 0.4-0.8 part of sorbitol, 1-5 parts of sodium chloride, 1-5 parts of cetyl pyridinium chloride monohydrate, 0.8-1.2 parts of protocatechuic acid, 2-6 parts of tea polyphenol, 0.4-0.8 part of acesulfame potassium, 0.2-0.6 part of polyphenols, 0.6-1 part of thymol crystals and 0.5-0.9 part of mint oil, wherein effective components of the plant raw materials are extracted and mixed with other raw materials, and are subjected to operation such as heating, stirring and ultrasonic dispersion, thereby preparing a finished product of the mouth wash. The mouth wash disclosed by the invention is used as an auxiliary product used in the radiotherapy period of oral cancer rehabilitation, has a effect of long-acting bacterium inhibition, can maintain oral micro environments, can promote anabrosis surface heal, can effectively alleviate the toxic and side effect in the radiotherapy period, can promote the anti-cancer effect, can improve the radiotherapy compliance, and has great clinical application values and wide market prospects.

Description

technical field [0001] The invention belongs to the technical field of toothpaste preparation, and in particular relates to a mouthwash used for rehabilitation treatment of oral cancer and a preparation method thereof. Background technique [0002] Oral cancer is a general term for malignant tumors that occur in the oral cavity. Most of them are squamous cell carcinomas. Oral cancer is one of the most common malignant tumors in the head and neck. Among the oral cancer cases, cancer of the active part of the tongue is the most common, followed by buccal cancer. Mucosal carcinoma: usually the farther the lesion is from the lip and closer to the oropharynx or the midline, the lower the degree of tumor differentiation and the higher the rate of lymph node metastasis. Early mucosal disease is only superficial nodules or superficial ulcers, which may be accompanied by mild Advanced lesions usually invade the underlying muscles or bones, causing organ fixation and language and swal...

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Problems solved by technology

[0002] Oral cancer is a general term for malignant tumors that occur in the oral cavity. Most of them are squamous cell carcinomas. Oral cancer is one of the most common malignant tumors in the head and neck. Among the oral cancer cases, cancer of the active part of the tongue is the most common, followed by buccal cancer. Mucosal carcinoma: usually the farther the lesion is from the lip and closer to the oropharynx or the midline, the lower the degree of tumor differentiation and the higher the rate of lymph node metastasis. Early mucosal disease is only superficial nodules or superficial ulcers, which may be accompanied by mild Advanced lesions usually invade the underlying muscles or bones, causing organ fixation and language and swallowing dysfunction; lymph node metastasis is mostly ipsilateral submandibular, subdigastric, upper neck or middle neck lymph nodes; beyond the oral cavity, tongue tip or The lesions on the midline of the floor of the mouth will have contralateral lymph node metastasis; the tumor size is different, and the metastasis rate is also different; the current treatment methods for oral cancer are: surgical resection, radiation therapy, and chemotherapy; early oral cancer if no cervical lymph nodes are seen For metastases, surgery or radiation therapy alone has a good therapeutic effect; for middle-advanced oral cancer, surgery combined with postoperative radiation therapy is more suitable; however, surgical resection, radiation therapy, and chemotherapy all have different side effects ;Drug adjuvant therapy is generally given during the treatment of oral cancer to alleviate the side effects during the treatment process. However, most of them use oral preparations at present, and enteral administration increases the burden on the liver and kidneys. Especially during radiotherapy, the patient's own physical strength is low and immunity is insufficient. Oral medicine is no longer the best method for oral cancer. It is extremely important to explore a method for oral cancer radiotherapy and chemotherapy rehabilitation that can effectively reduce the toxic and side effects of radiotherapy and chemotherapy, promote the anticancer effect, and improve the compliance of radiotherapy and chemotherapy. research-worthy

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