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Bioactive functional dressing for treating diabetic feet

A bioactive, diabetic foot technology, applied in medical science, absorbent pads, bandages, etc., can solve the problems of not being able to really play an anti-infective effect, unable to meet the huge market demand, and not considering nerve damage, etc. The effect of suction and discharge of pus from infected wound surface, simple structure and low production cost

Inactive Publication Date: 2017-06-27
JINAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0018] (1) It is not considered comprehensively that diabetic foot is a complex result of vascular disease, neuropathy, impaired immune function and infection, and its complexity, while existing inventions or products only consider one or two functions, such as only Simply introduce growth factors, or add antibacterial, or add liquid absorption, etc., so the comprehensive effect is not good;
[0019] (2) All inventions do not take into account the condition of nerve damage, so the dressing does not take corresponding functions;
[0020] (3) Some dressings use chitosan as an antibacterial material. In fact, simple chitosan is effective against Gram-negative bacteria, Pseudomonas aeruginosa and drug-resistant Pseudomonas aeruginosa, Pseudomonas aeruginosa, and Candida albicans. , anthrax and other effects are not significant enough to really play an anti-infection role;
[0021] (4) There are very few domestically produced high-end functional dressings, which cannot meet the huge demand of the market;
[0022] (5) The prices of dressings used clinically by foreign companies in China are generally high

Method used

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  • Bioactive functional dressing for treating diabetic feet
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Examples

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Effect test

Embodiment 1

[0052] A bioactive functional dressing for the treatment of diabetic feet, such as figure 1 and figure 2 As shown, it consists of four parts: biologically active functional layer, antibacterial functional layer, liquid-absorbing functional layer, and biological pressure functional layer. The biologically active functional layer is the lowest layer, the second layer from bottom to top is the antibacterial functional layer, the third layer is the liquid-absorbing functional layer, and the fourth layer (the uppermost layer) is the biological pressure functional layer. The bioactive functional layer is composed of active scaffolds, nerve growth factors, EGF, bFGF, antithrombotic enzymes and other materials. Active substances such as nerve growth factor, EGF, bFGF, and antithrombotic enzyme are loaded on the active scaffold. The active scaffold is produced by electrospinning of type I collagen, on which self-assembled active peptides are compounded. The self-assembly active pep...

Embodiment 2

[0058] A bioactive functional dressing for the treatment of diabetic feet, such as figure 1 and figure 2 As shown, it consists of four parts: biologically active functional layer, antibacterial functional layer, liquid-absorbing functional layer, and biological pressure functional layer. The biologically active functional layer is the lowest layer, the second layer from bottom to top is the antibacterial functional layer, the third layer is the liquid-absorbing functional layer, and the fourth layer (the uppermost layer) is the biological pressure functional layer. The bioactive functional layer is composed of active scaffolds, nerve growth factors, EGF, bFGF, antithrombotic enzymes and other materials. Active substances such as nerve growth factor, EGF, bFGF, and antithrombotic enzyme are loaded on the active scaffold. The active scaffold is produced by electrospinning of type I collagen, on which self-assembled active peptides are compounded. The self-assembly active pep...

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Abstract

The invention discloses bioactive functional dressing for treating diabetic feet. The dressing comprises a bioactive functional layer, an antibacterial functional layer, a fluid absorption functional layer and a biotic pressure functional layer sequentially from the bottom up. The dressing is simple in structure and low in production expense, low in cost and convenient to operate at the same time, greatly facilitates treatment of diabetic foot wounds of a doctor and medical care personnel; an active ingredient of the bioactive functional layer has a slow release effect; the dress can effectively stimulate and promote cell activation and regeneration of the surfaces of the diabetic foot wounds and promotes capillary network and nerve repair of the surfaces of the wounds by the action of the biological active ingredient. The dressing has effects of repairing neural and vascular lesions, efficiently resisting infection, absorbing fluid and evacuating pus on the surfaces of the wounds, and a biomechanical effect on the wounds, is multifunctional and good in treatment effect and can be widely applied to clinical treatment and nursing of the diabetic feet.

Description

technical field [0001] The invention relates to a functional dressing in medical equipment, in particular to a bioactive functional dressing for treating diabetic foot. Background technique [0002] With the development of the economy, the change of people's lifestyle and the aging population, the number of diabetic patients (mainly type 2 diabetes) is increasing rapidly, presenting an epidemic trend. According to a report from the World Health Organization, in 2013, 382 million adults around the world suffered from diabetes. Diabetes has become a common and frequently-occurring disease in many countries around the world, and its mortality rate ranks third after cardiovascular diseases and tumors. [0003] Compared with developed countries, the prevalence of diabetes in my country is still relatively low, but the rate of increase in the prevalence of diabetes in my country is the fastest in the world. Coupled with our large population base, the number of people with diabetes...

Claims

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Application Information

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IPC IPC(8): A61L15/32A61L15/28A61L15/24A61L15/20A61L15/44A61L15/46A61L15/42
CPCA61L15/325A61L15/20A61L15/24A61L15/28A61L15/42A61L15/425A61L15/44A61L15/46A61L2300/208A61L2300/252A61L2300/254A61L2300/404A61L2300/412A61L2300/414C08L5/08C08L1/286C08L33/12
Inventor 敖宁建许楗桢顾留群
Owner JINAN UNIVERSITY
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