High-sensitivity biochemical sensor cascaded with polymer microdisks and liquid microcavities
A biochemical sensor and high-sensitivity technology applied in the field of sensors to achieve stable performance, simple and compact structure, and strong practical application value
Active Publication Date: 2019-12-03
UNIV OF ELECTRONICS SCI & TECH OF CHINA
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[0003] The purpose of the present invention is: in order to solve the shortcomings of the existing planar optical waveguide resonator sensor using evanescent field sensing, the present invention proposes a polymer microdisk and liquid microcavity with simple and compact structure, low manufacturing process difficulty, and easy integration Cascaded high-sensitivity biochemical sensors
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[0020] In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.
[0021] Such as figure 1 As shown, it is a schematic structural diagram of a high-sensitivity biochemical sensor in which the polymer microdisk and the liquid microcavity are cascaded in the present invention. A high-sensitivity biochemical sensor in which a polymer microdisk and a liquid microcavity are cascaded, comprising a substrate, a lower cladding layer 1 and an upper cladding layer stacked sequentially from bottom to top; the lower cladding layer 1 is provided with a single A mode waveguide 4, the two ends of the single-mode waveguide 4 are respectively provided with an optical input end 2 ...
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The invention discloses a high-sensitivity biochemical sensor in which a polymer microdisk and a liquid microcavity are cascaded. It includes a substrate, a lower cladding layer and an upper cladding layer stacked sequentially from bottom to top; the lower cladding layer is provided with a single-mode waveguide that runs through its upper surface, and the two ends of the single-mode waveguide are respectively provided with an optical input port and an optical output end; the end of the single-mode waveguide connected to the optical input end is provided with a first arc portion, and the end connected to the optical output end is provided with a second arc portion; the first arc portion A reference microdisk is arranged on the outside, and the reference microdisk is connected to the first arc portion through a first multimode interference coupler; a liquid microcavity is arranged on the outside of the second arc portion, and the liquid microcavity passes through the first arc portion. Two multimode interference couplers are connected to the second arc portion. The invention has the advantages of simple and compact structure, stable performance, easy integration and scale, strong anti-electromagnetic interference ability, and strong practical application value in the field of low-concentration biological detection.
Description
technical field [0001] The invention belongs to the technical field of sensors, in particular to a high-sensitivity biochemical sensor in which a polymer microdisk and a liquid microcavity are cascaded. Background technique [0002] Optical biosensors are widely used in clinical analysis, medical diagnosis, food and drug safety and environmental detection due to their advantages of high sensitivity, anti-electromagnetic interference, multi-functional integration and high flexibility. However, cancer, AIDS, and some rapidly spreading viruses (SARS, Ebola) are still huge threats to human health. In order to solve these problems, it is necessary to quickly and reliably detect the characteristics of extremely low concentrations of biomolecules in the field of molecular detection. Not only higher requirements are placed on the performance of biosensors, but also more requirements are placed on the portability, specificity and integration characteristics of sensors. Among them, t...
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IPC IPC(8): G01N21/45
CPCG01N21/45G01N2021/458
Inventor 王玲芳郭峰
Owner UNIV OF ELECTRONICS SCI & TECH OF CHINA