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Flow detection device having at least one electrically actuated fluid flow control valve and associated method

A detection device and a technology for detecting samples, applied in fluid controllers, measuring devices, chemical instruments and methods, etc., can solve problems such as limited chemical reaction complexity

Active Publication Date: 2019-09-20
TOKITAE LLC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is a limit to the complexity of the chemical reactions that can be performed in the LFA without flow control

Method used

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  • Flow detection device having at least one electrically actuated fluid flow control valve and associated method
  • Flow detection device having at least one electrically actuated fluid flow control valve and associated method
  • Flow detection device having at least one electrically actuated fluid flow control valve and associated method

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Embodiment Construction

[0022] Embodiments disclosed herein relate to flow detection devices (eg, LFAs) that include electrically actuated valves configured to control fluid flow. Methods of operating such microfluidic detection devices are also disclosed.

[0023] The LFA can be used to provide, without limitation, point-of-care testing for a variety of purposes, such as drug testing, pregnancy testing, flu testing, fertility testing, human immunodeficiency virus ("HIV") testing, hepatitis testing. LFAs function by moving a sample containing an analyte therein through the length of a capillary bed via capillary action. During capillary transport, the analyte in the sample is exposed to a conjugate material configured to react with the analyte to facilitate its detection. The conjugate contains a marker or coloring molecule. The marker or colored molecule is configured to react with the analyte, reacted analyte molecule, or analyte-conjugate complex and provide a visual indication thereof when subs...

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Abstract

Embodiments disclosed herein relate to flow detection devices comprising at least one electrically actuated valve configured to control fluid flow. A method of operating such a flow detection device is also disclosed.

Description

[0001] All subject matter of the priority application is incorporated herein by reference to the extent that such subject matter is not inconsistent with this document. technical field [0002] The present invention relates to fluid detection, and more particularly to flow detection devices and related methods. Background technique [0003] A lateral flow assay device ("LFA") can be a paper-based device that detects the presence of an analyte in a sample without the need for expensive equipment. LFA is a common nursing diagnostic tool. [0004] LFAs act by wicking (eg, capillary action) the sample under study through a porous membrane (eg, paper), where chemical reactions can occur within and on the surface of the porous membrane. The LFA may contain conjugated material therein. Conjugate materials are typically formulated to provide the solvents and reactants necessary to dissolve, react, stain, label, or bind the analyte of interest in the sample. Thus, if an analyte is...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N33/487
CPCG01N33/48721B01L3/5023B01L3/502738B01L2300/0645B01L2300/0825B01L2400/0406B01L2400/0427B01L2400/0688B01L3/502784B01L3/502792G01N27/447
Inventor 大卫·葛司培瑞诺凯文·保罗·弗洛德·尼克尔斯本杰明·K·威尔逊奥祖尔·埃梅克·伊尔迪里姆
Owner TOKITAE LLC