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Puji rejuvenation pill as well as preparation method and application thereof

A technology of Huichun pills and pills, which is applied in the field of medicine to achieve the effect of reducing the dosage

Inactive Publication Date: 2017-09-22
NANJING JINGYUN CHEM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It is used for wind-heat epidemic toxin in children, fever and headache, redness and swelling of the head and face, sore throat, mumps, and facial erysipelas. At present, there is no literature report on the preparation of honeyed pills after extraction by the present invention and treatment of diabetes

Method used

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  • Puji rejuvenation pill as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0007] Example 1: Coptidis 3g, fried burdock 80g, baicalin 10g, bran fried silkworm 80g, tangerine peel 20g, isatidis 160g, licorice 20g, bellflower 20g, forsythia 80g, puffball 80g, scrophulariaceae 20g, mint 80g, cinnabar 24g , Bupleurum 80g, Cimicifuga 80g, the preparation method is: the above fifteen flavors, beat into coarse powder, add water to decoct once, each time decoct for 3 hours, combine the decoction, filter, concentrate the decoction to 40 degrees and measure The clear paste with a relative density of 1.15, after cooling to room temperature, add ethanol to make the alcohol content 50%, stir well, refrigerate for 72 hours, take the supernatant, filter, recover the ethanol from the filtrate, concentrate to 45 degrees to measure the relative density of 1.40 The extract, spray-dried, mixed evenly, added 50g of refined honey per 100g to make small honeyed pills, microwave-dried for 15 minutes under the condition of microwave 250w hot air 40°C, hot air-dried for 2 hour...

Embodiment 2

[0008] Example 2: Take 3g of Coptis chinensis, 80g of fried burdock, 10g of skullcap, 80g of fried silkworm with bran, 20g of orange peel, 160g of Radix Radix, 20g of licorice, 20g of bellflower, 80g of forsythia, 80g of puffball, 20g of scrophulariaceae, 80g of mint, and cinnabar 24g, Bupleurum 80g, Cimicifuga 80g, the preparation method is: the above fifteen flavors, beat into coarse powder, add water and decoct 3 times, each decoction for 1 hour, combine the decoction, filter, and concentrate the decoction to 60 Measure the clear paste with a relative density of 1.05, wait until it is cooled to room temperature, add ethanol to make the alcohol content 50-70%, stir well, refrigerate for 24 hours, take the supernatant, filter, recover the ethanol from the filtrate, concentrate to 60 degrees and measure The extract with a relative density of 1.20, spray-dried, mixed evenly, added 60g of refined honey per 100g to make small honey pills, microwave-dried for 15 minutes under the c...

Embodiment 3

[0009] Embodiment 3: the influence of the present invention on diabetic rats

[0010] Experimental drug: prepared according to the method of Example 1.

[0011] Experimental process: SD rats with a body weight of 160-180g, half male and half male, were first fed with high-fat and high-sugar feed (selected protein 5%, carbohydrate 60% including 30% sucrose, fat 32% including refined lard 30%) After 4 weeks, the rats were fasted for 18 hours. Intraperitoneal injection of 0.6% streptozotocin (STZ) 30mg / kg, STZ dissolved in pH4.0, 0.1mol / L citric acid-sodium citrate buffer, each dose used up within 10min. Rats in the blank group were injected intraperitoneally with an equal volume of citric acid-sodium citrate buffer, and were fed normally. After 5 days, blood was taken from the tail to measure the blood glucose, and the modeling was successful if the blood glucose level was greater than 10.0mmol / L. Successful model rats were randomly divided into the following groups according...

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Abstract

The invention discloses a Puji rejuvenation pill. The Puji rejuvenation pill is prepared by extracting from the following raw material medicines: 3 g of rhizoma coptidis, 80 g of fried fructus arctii, 10 g of radix scutellariae, 80 g of bombyx batryticatus stir-fried with bran, 20 g of pericarpium citri reticulatae, 160 g of radix isatidis, 20 g of liquorice root, 20 g of radix platycodi, 80 g of fructus forsythiae, 80 g of sporocarp of lasiosphaera seu calvatia, 20 g of radix scrophulariae, 80 g of herba menthae, 24 g of cinnabaris, 80 g of radix bupleuri and 80 g of rhizoma cimicifugae. The Puji rejuvenation pill is found to be able to treat diabetes.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a Puji Huichun Pill and its preparation method and application. Background technique [0002] Puji Huichun Pills, recorded in the Ministry of Health standard (standard number: WS3-B-0156-89), the prescription is Coptidis 3g, fried burdock 80g, scutellaria baicalensis 10g, bran fried silkworm 80g, tangerine peel 20g, Radix Radix 160g, licorice 20g , Platycodon 20g, Forsythia 80g, Puffball 80g, Scrophulariaceae 20g, Mint 80g, Cinnabar 24g, Bupleurum 80g, Cimicifuga 80g, the preparation method is: the above fifteen flavors, except cinnabar water flying or crushed into very fine powder , Coptidis and other fourteen flavors are crushed into fine powder, blended with the above powder, sieved, and mixed. Add 130-150g of refined honey to every 100g of powder to make big honeyed pills. It is used for children with wind-heat and epidemic toxin, fever and headache, redness and swelling of the head...

Claims

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Application Information

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IPC IPC(8): A61K36/808A61K9/28A61P3/10A61P31/14A61P11/04A61P31/00A61K35/64A61K33/28
CPCA61K36/808A61K9/2813A61K33/28A61K35/63A61K36/07A61K36/195A61K36/233A61K36/28A61K36/315A61K36/346A61K36/484A61K36/534A61K36/539A61K36/634A61K36/71A61K36/718A61K36/752A61K2236/331A61K2236/51A61K2236/55A61K2300/00
Inventor 戴文健
Owner NANJING JINGYUN CHEM
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