Diffusion MRI microstructure imaging-based minimum nuclear error analysis method
An error analysis and microstructure technology, applied in the fields of neuroanatomy and medical imaging, which can solve problems such as the inability to estimate stably and efficiently
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[0039] The present invention will be further described below.
[0040] A minimum nuclear error analysis method based on diffusion MRI microstructure imaging, comprising the following steps:
[0041] (1) Establish a diffusion organization model:
[0042] NEMI proposes a new microstructure model that contains three characteristics of microstructure: linear structural anisotropy (LSA, D l ), planar structural anisotropy (PSA, D p ) and spherical structure isotropy (SSI, D s ); in general, each feature model in each voxel can be described as a mixed anisotropy / isotropy model:
[0043]
[0044] where S(0) represents the baseline signal, D i Indicates the subset i diffusion tensor, b indicates the gradient direction, g indicates the gradient direction, m indicates the maximum number of subsets that have intersections with m cardinal directions in a voxel, f i Indicates the volume fraction of subset i;
[0045] A linear combination blend of three microstructural models:
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