Noninvasive determination of cardiac health and other functional states and trends for human physiological systems

Abstract

This document describes the assessment of human physiological systems in a manner that can be applied throughout the population. Various noninvasive sensors (including wearable, passive contact and noncontact sensors) may be integrated into the furniture of a person's home (including a mat, a toilet-seat, a mirror and a bathtub). They can be used to detect vitals and other parameters and combined with mathematical models to assess the functional state of physiological systems. For example, the health of the cardiovascular system is ultimately determined by organ blood perfusion and molecular gas exchange. In lieu of measuring these functional metrics directly, noninvasive sensors are used to monitor cardiac pressures and volumes, along with pressure transit through the vascular to quantify cardiovascular health, presenting little if any risk to the person and are simple and easy to use. In particular, cardiac pressure-volume loops are determined at different points in time and a health trend for the physiological system is determined based thereon.

Description

[0001] priority application [0002] This application claims priority under 35 U.S.C. §120 to U.S. Utility Patent Application No. 14 / 599,954, filed January 19, 2015, entitled "Noninvasive Determination of Cardiac Health and Other Functional States and Trends for Human Physiological Systems" , the content disclosed in this application is incorporated herein by reference in its entirety. Background technique [0003] Cardiovascular disease is a major cause of morbidity, mortality and cost worldwide. At the same time, this chronic disease is largely preventable. Medical science knows how to save most of these lives by eliminating major risk factors such as smoking, diabetes and high blood pressure. And, many were told what they only needed to do to reduce these risk factors: stop smoking, reduce sugar intake, eat healthier, reduce alcohol consumption, increase cardiovascular exercise, lose weight, and, if necessary, take blood pressure drug. However, many people will not foll...

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They may see that they have lost weight and perhaps see their blood

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