Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A kind of preparation method of solanum nigrum formula granule

A formula granule and solanum nigrum technology, which is applied in pharmaceutical formulas, medical preparations containing active ingredients, extracellular fluid diseases, etc., can solve the problems of low content transfer rate, high loss of solanine and solanine , to achieve the effect of prolonging the extraction time, increasing the content transfer rate and increasing the concentration

Active Publication Date: 2020-11-24
SHINEWAY PHARMA GRP LTD
View PDF8 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to provide a preparation method of Solanum nigrum formula granules to solve the problems of excessive loss of solanine and solanine solanine in Solanum nigrum formula granules and low content transfer rate

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of preparation method of solanum nigrum formula granule
  • A kind of preparation method of solanum nigrum formula granule
  • A kind of preparation method of solanum nigrum formula granule

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0027] A preparation method of nightshade fruit formula granules, said preparation method at least comprising the following steps:

[0028] Step 1, removing impurities and crushing fresh nightshade fruit to obtain decoction pieces;

[0029] Step 2, sequentially performing the first alcohol extraction and the second alcohol extraction on the decoction pieces to obtain the alcohol extract;

[0030] Step 3. Carrying out the first water extraction and the second water extraction sequentially on the medicinal dregs obtained through the second alcohol extraction to obtain a water extract;

[0031] Step 4. Concentrate the water extract in a vacuum environment below 80°C to obtain the first extract with a relative density of 1.07-1.09; place the alcohol extract in a vacuum environment for concentration , until there is no alcohol smell, the second extract is obtained;

[0032] Step 5, performing mixing treatment on the first extract and the second extract, followed by vacuum microwa...

Embodiment 1

[0057] The present embodiment provides a kind of preparation method of solanum nigrum formula granule, and described preparation method comprises the following steps at least:

[0058] Step 1, removing impurities and crushing fresh nightshade fruit with a total alkaloid content of not less than 12 mg / g, obtaining decoction pieces, and putting them into an extraction tank;

[0059] Step 2, sequentially performing the first alcohol extraction and the second alcohol extraction on the decoction pieces to obtain the alcohol extract;

[0060] The first alcohol extraction treatment is to add ethanol whose mass is 10 times that of the decoction pieces and whose volume concentration is 80% to the decoction pieces, soak for 24 hours, and collect the extract and medicinal residues; the second alcohol extraction The extraction process is to add ethanol with a volume concentration of 65% whose mass is 8 times the mass of the medicinal residues to the medicinal residues, and reflux extracti...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the technical field of processing of traditional Chinese medicine processing and provides a preparation method of nigrum fruit formula granules. The preparation method comprises the following steps: carrying out edulcoration and crushing on fresh nigrum fruits, so as to obtain medicinal slices; carrying out alcohol extraction twice and water extraction twice on the medicinal slices; carrying out concentration; and carrying out vacuum microwave drying so as to obtain a mixed material, adding dextrin, and carrying out granulation, so as to obtain the nigrum fruit formula granules. The alcohol extraction and the water extraction are carried out twice, the concentrations, time and temperatures of the alcohol extraction and the water extraction are controlled, and then the vacuum microwave drying is carried out, so that the content transfer rates of solasonine and solamargine in the nigrum fruit formula granules are increased, and each 1g of the prepared nigrum fruit formula granules is equal to 5.0g of the weight of a medicinal slice.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine processing, and more specifically relates to a preparation method of Solanum nigrum formula granules. Background technique [0002] Solanum nigrum formula granule is the immature fruit of nightshade plant (Soalnum nigrum L.). In summer, the fruit is harvested before it is ripe, treated with ethanol to keep fresh, and sealed in bags. This taste is bitter, slightly sour, cold in nature, has the effects of clearing heat and detoxifying, reducing swelling and dissipating stagnation, reducing inflammation and diuresis, promoting body fluid and quenching thirst. For febrile bronchitis, pharyngitis, gastritis, hepatitis, urinary tract infection, dysuria, tumor. [0003] Solanine and solanine in Solanum nigrum fruit are the main anticancer active ingredients, and the in vitro cell test shows ideal anticancer activity. Australian solanine and Australian solanine are glycoside alkalo...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/16A61K36/81A61P11/00A61P11/04A61P1/04A61P1/16A61P13/04A61P31/00A61P7/10A61P35/00
CPCA61K9/1652A61K9/1682A61K36/81A61K2236/331A61K2236/333A61K2236/39A61K2236/51
Inventor 李军山马爱华郝磊孙福仁常云凤李振江
Owner SHINEWAY PHARMA GRP LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com