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Blood separation pretreatment chip and blood separation device

A blood separation and pretreatment technology, applied in the field of biomedicine, can solve the problems of high cost, long blood consumption, and reduced detection efficiency of blood samples, so as to achieve the effect of improving detection efficiency and rapid separation

Pending Publication Date: 2017-10-20
深圳市华讯方舟光电技术有限公司 +1
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  • Abstract
  • Description
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  • Application Information

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Problems solved by technology

This serum separation method requires a large amount of blood and takes a long time, which seriously reduces the detection efficiency of blood samples

Method used

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  • Blood separation pretreatment chip and blood separation device
  • Blood separation pretreatment chip and blood separation device
  • Blood separation pretreatment chip and blood separation device

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Embodiment Construction

[0028] In order to enable those skilled in the art to better understand the solutions of the present invention, the technical solutions in the embodiments of the present invention will be clearly described below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are the embodiment of the present invention. Some examples, but not all examples. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts shall fall within the protection scope of the present invention.

[0029] The terms "comprising" and any variations thereof in the description and claims of the present invention and the above drawings are intended to cover non-exclusive inclusion. For example, a process, method or system, product or device comprising a series of steps or units is not limited to the listed steps or units, but optionally also inc...

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Abstract

The invention provides a blood separation pretreatment chip and a blood separation device. The pretreatment chip includes at least one microcolumn array arranged along the blood flow direction in order, column spacings between the microcolumn arrays are different, the column spacing of the at least one microcolumn array decreases successively according to the arrangement order of the at least one microcolumn array, and the at least one microcolumn array at least includes a red blood cell intercepted microcolumn array, the red blood cell intercepted microcolumn array intercepts red blood cells in blood to filter out red blood cells from the blood. Blood flows in from an inlet of the blood separation pretreatment chip, and undergoes interception and filtration by the at least one microcolumn array in order, thus obtaining blood plasma containing red blood cells and platelets with the amount being lower than a preset amount, and the obtained blood plasma then flows out from a blood separation pretreatment chip outlet. The blood separation pretreatment chip and the blood separation device provided by the invention can realize fast separation of a small amount of blood samples, and improve the blood sample detection efficiency.

Description

technical field [0001] The embodiments of the present invention belong to the technical field of biomedicine, and in particular relate to a blood separation pretreatment chip and a blood separation device. Background technique [0002] During the treatment of cancer patients, the quality of the treatment can be measured by the response results of various marker molecules (such as protein, miRNA (MicroRNA, non-coding single-stranded RNA molecule)) in the blood. Usually, a blood tester is used to detect the blood samples of cancer patients, which can realize non-destructive detection of cancer patients, monitor the patient's condition in real time, provide an important basis for doctors to adjust reasonable treatment plans in time, and provide accurate medical testing. solid foundation. [0003] However, in addition to biomolecules such as proteins and miRNAs, blood also contains a large number of cells of different sizes. In order to improve the detection sensitivity and re...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00
CPCB01L3/502707B01L3/502753B01L3/502761B01L2200/10B01L2300/0832B01L2300/0636
Inventor 韩琳丁庆刘荣跃杨彬李辰
Owner 深圳市华讯方舟光电技术有限公司
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