57 results about "Blood separation device" patented technology

A method for carrying out therapeutic apheresis comprises separating plasma from whole blood in-vivo and removing selected disease-related components from the separated plasma. Apparatus for carrying out therapeutic apheresis includes a filter device for being implanted in a blood vessel for carrying out in-vivo plasma separation having one or more elongated hollow tubes and a plurality of elongated hollow microporous fibers capable of separating plasma from whole blood at pressure and blood flow within a patient's vein, a multiple lumen catheter secured to the proximal end of the filter device having one or more lumens in fluid communication with the interior of said one or more hollow tubes and a plasma return lumen, and therapeutic apheresis apparatus for removing and/or separating selected disease-related components from the separated plasma and means for directing plasma between said catheter and the selective component removal apparatus.

Systems and methods for providing for the automatic instrument-based rapid reprocessing of an intact extracorporeal circuit for use in hemodialysis. The system includes a manifold with connectors for engaging a dialyzer as well as venous and arterial blood lines. The manifold is adapted to be moved from a dialysis machine to a reuse instrument without removing the dialyzer and associated blood lines. The system allows for reprocessing of the extracorporeal circuit wherein prior to the next treatment, there is no residual chemical disinfectant requiring testing, the extracorporeal circuit is pre-primed, the levels in the bubble traps are set, and all of the required quality assurance tests are performed and recorded.

Systems and methods are provided for automatically adjusting the operational parameters of a blood separation procedure. A blood separation device has an inlet for passing fluid thereinto and an outlet for removing fluid therefrom. A pump system is provided for moving fluid into and out of the device. In use, blood is conveyed into the device, where platelets are separated from at least a portion of the blood. A controller determines the amount of platelets in the device. Based at least in part on the amount of platelets in the device, corrective action is taken to avoid platelet aggregation in the device. The corrective action may be conveying an elevated amount of anticoagulant into the blood and/or the device and may be initiated when the determined amount of platelets approaches, meets, or exceeds a threshold predicted likelihood of platelet aggregation.

A disposable blood separation set and a centrifugal blood processing system comprising a blood processing chamber adapted to be mounted on a rotor of a centrifuge; a frustro-conical cell separation chamber in fluid communication with the processing chamber, the cell separation chamber having an inlet, and outlet and a side tap outlet adjacent the inlet. The inlet may protrude into the cell separation chamber forming a circumferential well surrounding the protruding inlet. The side tap outlet may connect to the well. The set and system comprise means for selectively drawing fluid from either the outlet or the side tap outlet.

A disposable blood separation set and a centrifugal blood processing system comprising a blood processing chamber adapted to be mounted on a rotor of a centrifuge; a frustro-conical cell separation chamber in fluid communication with the processing chamber, the cell separation chamber having an inlet, a primary outlet and a side tap outlet adjacent the inlet. A valve that is responsive to centrifugal force (a “gravity” valve) selects between the outlet and the side tap outlet. The gravity valve is mounted on the rotor. When the rotor spins at high speed, the gravity valve may open the primary outlet and close the side tap outlet. When the rotor spins at a lower speed, the gravity valve may open the side tap outlet and close the primary outlet.

In one embodiment of the present invention, provided is a blood separating device comprising: a first kit which comprises a first space for receiving blood on the inside thereof, and wherein the first space is separated between top and bottom by means of a first opening part; a second kit which comprises a second space for receiving blood on the inside thereof, and wherein the second space is separated between top and bottom by means of a second opening part; a plate which is disposed between the first kit and the second kit, and is provided with a through-connection hole for establishing fluid through connection of the first space and the second space; a stopper having a first bar which is provided projecting upwards from the plate and opens and closes the first opening part, and a second bar which is provided projecting downwards from the plate and opens and closes the second opening part; a first cap which covers the upper end part of the first kit; and a second cap which covers the bottom end part of the second kit. The stopper allows blood to be separated a plurality of times by respectively opening and closing the first opening part and the second opening part.

A blood separation device adapted to receive a blood sample having a whole blood portion and a plasma portion is disclosed. The blood separation device includes a housing defining a first chamber, a second chamber, and a separation member disposed therebetween. The blood separation device also includes an actuator, wherein actuation of the actuator draws the blood sample into the first chamber and the separation member is adapted to allow the plasma portion to pass through the separation member to the second chamber. The blood separation device matches the plasma chamber volume, the blood chamber volume, and the applied single pressure source so that the correct trans-membrane pressure and shear rate is obtained.

Programmable, fluid pressure actuated blood processing systems and methods are used in association a blood separation device. The systems and methods employ a cassette, which contains several preformed, pneumatically actuated pump stations, several preformed fluid flow paths, and several preformed, pneumatically actuated valves in the fluid flow paths. The systems and methods also employ a programmable pneumatic actuator to hold the cassette and selectively apply pneumatic force to the valves and pump stations.

A disposable blood separation set and a centrifugal blood processing system comprising a blood processing chamber adapted to be mounted on a rotor of a centrifuge; a frustro-conical cell separation chamber in fluid communication with the processing chamber, the cell separation chamber having an inlet, an outlet and a gravity valve inside the cell separation chamber. The valve is responsive to the gravitational field created by the speed of the rotor. When the rotor spins at high speed, the gravity valve may open the outlet at a location proximal to an axis of rotation of the rotor. When the rotor spins at a lower speed, the gravity valve may open the outlet at a location distal from the axis.

A disposable blood separation set of a centrifugal blood processing system comprising a blood processing chamber adapted to be mounted on a rotor of a centrifuge; a frustro-conical cell separation chamber in fluid communication with the processing chamber, the cell separation chamber having a protruding inlet therein. The protruding inlet may have a frustro-conical inner surface that slants radially outwardly from an inlet to a mouth of the protruding inlet. A circumferential well may surround the protruding inlet. The cell separation chamber may have a baffle within a separation area. The baffle may have a plurality of vanes with openings therein.

The invention relates to a blood separation device and a separation method, in particular to a blood separation device and a separation method used for filtrating leucocyte. The blood separation device comprises a piston pump device, a stepping motor and a control used for driving the piston pump device, a separation box, a raw blood bag, a vacuum bag communicated with the liquid conveying outlet of the separation box, and a waste liquid bag which is communicated with the waste liquid outlet of the separation box; the blood separation device and the separation method are characterized in that the inlet and outlet of the piston pump device, the liquid conveying inlet of the separation box and the raw blood bag are communicated with each other by a three-way pipe; the raw blood bag is arranged at high attitude so as to carry out the blood separation; the stepping motor is controlled, the piston rod of the piston pump reciprocates, the blood flows, and the filtrated blood is collected at the same time.

A blood separation device that is adapted to receive a multi-component blood sample is disclosed. After collecting the blood sample, the blood separation device is able to separate a plasma portion from a cellular portion. After separation, the blood separation device is able to transfer the plasma portion of the blood sample to a point-of-care testing device. The blood separation device also provides a closed sampling and transfer system that reduces the exposure of a blood sample and provides fast mixing of a blood sample with a sample stabilizer. The blood separation device is engageable with a blood testing device for closed transfer of a portion of the plasma portion from the blood separation device to the blood testing device. The blood testing device is adapted to receive the plasma portion to analyze the blood sample and obtain test results.

The invention discloses a blood separating device. The device is a porous polymer layer prepared from hydrophilic epoxy-based materials, communicating holes are uniformly distributed in the porous polymer layer, so that when blood is injected, blood cells in the blood are blocked by the communicating holes, and plasma in the blood flows through the communicating holes. The invention further discloses a blood separation detecting device which comprises a second bracket, the blood separating device and a first bracket, and a blood separation detecting method. According to the invention, through the use of the porous polymer layer, blood separation is realized, the blood separation and blood detection are integrated together, a small amount of the blood can be detected, the devices disclosed by the invention have the advantages that the structures are simple, the costs are low, and the operations are convenient, so that the devices and the method are suitable for daily use.

Apparatus, system and method are provided for controlling flow through a biological fluid processing device. Pressure of fluid flow through a flow path is monitored and flow rate in the flow path is increased or decreased based on sensed pressure levels for selected periods of time. This has particular application in controlling flow in an infusion or return flow path of an apheresis device that separates whole blood into one or more blood components.

The invention relates to a device (1) for separating blood individually and/or in groups of components thereof, in the form of a sterisable system comprising a filter arrangement (2), which forms an inlet chamber (4) and an outlet chamber (5) by means of a filter element (3) which is arranged therein, a receptacle (6) for cellular blood components and a receptacle (7) for blood plasma.The inlet chamber (4) of the filter arrangement (2) can be connected to the blood source (10) via a line on the inlet side and is connected, on the outlet side, to the receptacle (6) for cellular components of the blood. The outlet chamber (5) is connected to the receptacle (7) for blood plasma via a line on the outlet side.; The aim of the invention is use thermal sterilisation, in particular vapour sterilisation, in order to sterilise said device.Said aim is achieved by virtue of the fact that a line (17, 20) is connected to the inlet-sided line (14) of the inlet chamber (4) or to the inlet chamber (4) and to the outlet-sided line (20) of the outlet chamber (5) or to the outlet chamber (5), in order to join towards the environment via a hydrophobic or hydrophilic filter, in particular hydrophobic or hydrophilic bacteria filter (18, 21).